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innisfree Youth Enhancing Treatment Essence with Black Tea + Peptides Versus Jin Jung Sung Soothing Moisture Skin Essence

innisfree Youth Enhancing Treatment Essence with Black Tea + Peptides Versus Jin Jung Sung Soothing Moisture Skin Essence This anti-aging essence is formulated around Niacinamide and Copper Tripeptide-1 to soften the look of wrinkles and brighten dull-looking

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

innisfree Youth Enhancing Treatment Essence with Black Tea + Peptides Versus Jin Jung Sung Soothing Moisture Skin Essence

This anti-aging essence is formulated around Niacinamide and Copper Tripeptide-1 to soften the look of wrinkles and brighten dull-looking skin.

This calming essence is formulated around Niacinamide and Ceramide NP to calm redness and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Camellia Sinensis Leaf Water 95%

Water

Propanediol

Glycerin

Niacinamide

1,2-Hexanediol

Camellia Sinensis Leaf Extract

Ethylhexylglycerin

Adenosine

Dextrin

Ectoin

Hyaluronic Acid

3-O-Ethyl Ascorbic Acid

Glutathione

Mannitol

Saccharomyces Cerevisiae Extract

Butylene Glycol

Centella Asiatica Flower/Leaf/Stem Extract

Glycine Max Polypeptide

Arginine/Lysine Polypeptide

Copper Tripeptide-1

Disodium EDTA

Acetyl Tetrapeptide-11

Caprylyl Glycol

Acetyl Heptapeptide-4

Sorbic Acid

Hexapeptide-9

Acetyl Hexapeptide-8

Sodium Hydroxide

Acetyl Octapeptide-3

Camellia Sinensis Leaf Water 95%, Water, Propanediol, Glycerin, Niacinamide, 1,2-Hexanediol, Camellia Sinensis Leaf Extract, Ethylhexylglycerin, Adenosine, Dextrin, Ectoin, Hyaluronic Acid, 3-O-Ethyl Ascorbic Acid, Glutathione, Mannitol, Saccharomyces Cerevisiae Extract, Butylene Glycol, Centella Asiatica Flower/Leaf/Stem Extract, Glycine Max Polypeptide, Arginine/Lysine Polypeptide, Copper Tripeptide-1, Disodium EDTA, Acetyl Tetrapeptide-11, Caprylyl Glycol, Acetyl Heptapeptide-4, Sorbic Acid, Hexapeptide-9, Acetyl Hexapeptide-8, Sodium Hydroxide, Acetyl Octapeptide-3

Pentylene Glycol

Hydrogenated Lecithin

Soluble Collagen

Hydroxydecyl Ubiquinone

Cyclodextrin

Broussonetia Kazinoki Root Extract

Ceramide NP

Brassica Oleracea Acephala Leaf Extract

Persea Gratissima Fruit Extract

Apium Graveolens Extract

Brassica Oleracea Italica Extract

Leontopodium Alpinum Extract

Prunus Amygdalus Dulcis Seed Extract

Sodium Hyaluronate

Madecassoside

Allium Sativum Bulb Extract

Vaccinium Angustifolium Fruit Extract

Cistus Incanus Flower/Leaf/Stem Extract

Gynostemma Pentaphyllum Leaf/Stem Extract

Avena Sativa Seed Extract

Ecklonia Cava Extract

Schisandra Chinensis Fruit Extract

Cucurbita Pepo Fruit Extract

Spinacia Oleracea Leaf Extract

Beta-Glucan

Undaria Pinnatifida Extract

Eruca Sativa Leaf Extract

Hydrolyzed Hyaluronic Acid

Hydroxypropyltrimonium Hyaluronate

Potassium Hyaluronate

Sodium Hyaluronate Crosspolymer

Sodium Acetylated Hyaluronate

Hexapeptide-11

Palmitoyl Pentapeptide-4

Palmitoyl Tripeptide-1

Tripeptide-1

Carbomer

Tromethamine

Pulsatilla Koreana Extract

Zanthoxylum Piperitum Fruit Extract

Usnea Barbata Extract

Polyglyceryl-10 Laurate

Water, Butylene Glycol, Niacinamide, Pentylene Glycol, 1,2-Hexanediol, Hydrogenated Lecithin, Glycerin, Soluble Collagen, Hydroxydecyl Ubiquinone, Propanediol, Cyclodextrin, Broussonetia Kazinoki Root Extract, Ceramide NP, Brassica Oleracea Acephala Leaf Extract, Persea Gratissima Fruit Extract, Apium Graveolens Extract, Brassica Oleracea Italica Extract, Leontopodium Alpinum Extract, Prunus Amygdalus Dulcis Seed Extract, Sodium Hyaluronate, Madecassoside, Allium Sativum Bulb Extract, Vaccinium Angustifolium Fruit Extract, Cistus Incanus Flower/Leaf/Stem Extract, Gynostemma Pentaphyllum Leaf/Stem Extract, Avena Sativa Seed Extract, Ecklonia Cava Extract, Schisandra Chinensis Fruit Extract, Caprylyl Glycol, Cucurbita Pepo Fruit Extract, Spinacia Oleracea Leaf Extract, Beta-Glucan, Undaria Pinnatifida Extract, Eruca Sativa Leaf Extract, Ethylhexylglycerin, Hyaluronic Acid, Hydrolyzed Hyaluronic Acid, Hydroxypropyltrimonium Hyaluronate, Potassium Hyaluronate, Acetyl Hexapeptide-8, Sodium Hyaluronate Crosspolymer, Sodium Acetylated Hyaluronate, Hexapeptide-9, Hexapeptide-11, Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-1, Tripeptide-1, Copper Tripeptide-1, Adenosine, Carbomer, Tromethamine, Pulsatilla Koreana Extract, Zanthoxylum Piperitum Fruit Extract, Usnea Barbata Extract, Polyglyceryl-10 Laurate

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative".

It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time.

The comparison to Botox does have limits because the molecule is water-loving and relatively large.

Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles.

So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging.

A 12 week human study of a multi-ingredient regimen containing this ingredient saw:

While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone).

Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations.

Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.

The way it works is fairly well mapped out:

Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.

The clinical backing is pretty solid too.

A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.

A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.

On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.

This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.

Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Copper Tripeptide-1 (GHK-Cu) is a skin repairing ingredient known for its ability to boost collagen, improve firmness, and support skin regeneration.

It is a complex made up of a naturally occurring peptide (glycine-histidine-lysine) and copper, an essential trace element.

While studying wound healing, researchers noticed GHK-Cu stimulated hair follicle enlargement and growth by keeping hair in its active growth phase longer. This has made it a promising ingredient for hair regrowth treatments.

Some people have reported increased facial hair. While GHK-Cu can make your hair follicles bigger, it usually doesn’t turn soft, barely-visible facial hairs into thick, dark ones.

Anecdotal reports suggest that overusing copper peptides might lead to premature aging due to excess free copper or enzyme imbalances. This claim isn’t backed by large-scale studies.

Unfortunately, there are limited human studies for this ingredient. While early results are promising, many studies are either small, in-vitro, or not rigorously controlled.

For example, there is a 1998 study that explored the effects of copper tripeptide, vitamin C, tretinoin, and melatonin on skin repair and collagen synthesis.

After one month, increased procollagen production was seen in 7 out of 10 participants using copper tripeptide (more than those using vitamin C, melatonin, or tretinoin.

While the study was exploratory, it offers early evidence that copper tripeptide may support collagen production. Larger, well-designed trials are still needed to confirm its potential and understand individual responses.

Read more about other common types of peptides here:

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Hexapeptide-9 is a signaling peptide that is made to mimic a fragment found naturally in collagen IV and XVII.

It is classified as a matrikine peptide and works by telling your skin cells (especially fibroblasts) to ramp up collagen and hyaluronic acid production.

In-vitro studies show it can enhance epidermal regeneration, boost synthesis of collagen types I, III, and IV, and improved markers of skin differentiation.

Think of skin differentiation like this: your skin cells are born at the bottom and slowly travel up to the surface as they "grow up". As they move up, they start producing specific proteins that make your skin do its job well. Two of these proteins are keratin (it makes your skin tough) and filaggrin (it breaks apart into tiny molecules to keep your skin hydrated). So Hexapeptide-9 has shown to help skin cells grow up properly and make stronger, more hydrated skin.

A manufacturer also reports increased collagen production by 117% and hyaluronic acid production by 267%.

Just know much of the published data comes from manufacturer-sponsored studies. There is a recent clinical trial showing promising anti-aging results but the evidence base is still growing.

Generally, this ingredient is well-tolerated and there's no harm in using it as a supportive ingredient in your routine.

Hyaluronic acid (HA) is a glycosaminoglycan (basically a long sugar chain) that your skin already makes on its own. In your skin, HA lives in the extracellular matrix and acts as the body's moisture reservoir.

Topically, HA is a humectant that binds water and helps skin look more plump, smooth, and hydrated.

The only catch is that HA isn't a single thing; it actually comes in a wide range of molecular weights (~50 - 2,000+ kDA) and size matters.

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

This is why the best HA serums blend the two sizes together so you get the best of both worlds.

The majority of cosmetic HA is produced by bacterial fermentation, typically using Streptococcus or Bacillus strains. Typical use levels in skincare sit around 0.1-2%.

A clinical study using a 0.2% low-molecular weight HA gel showed improvement in facial seborrheic dermatitis with excellent tolerance.

These are some other common types of Hyaluronic Acid:

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

Connected reading

Helpful context for this guide

Source-derived material selected through this article’s indexed topics.

Research context

Read sources and limitations before applying a claim.

Case Studies and Research

Numerous case studies and research have demonstrated the effectiveness of functional medicine in managing chronic diseases. For example, a study published in the Journal of Clinical Rheumatology found that functional medicine approaches can significantly improve symptoms and quality of life in patients with rheumatoid arthritis. Another study published in the Journal of Alternative and Complementary Medicine found that functional medicine interventions can reduce blood pressure and improve cardiovascular health in patients with hypertension. These studies highlight the importance of functional medicine in addressing the root causes of chronic diseases and promoting optimal health and well-being.

Source: yoodirecthealth.com ↗
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Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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