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Next 10 U.S. Biopharma Clusters For the first time, GEN‘s Alex Philippidis examines the top regions and top states just below the 10 largest regions for life sciences activity, as the field looks beyond the East and West Coasts for growth. Thanks to booming sa

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Next 10 U.S. Biopharma Clusters

For the first time, GEN‘s Alex Philippidis examines the top regions and top states just below the 10 largest regions for life sciences activity, as the field looks beyond the East and West Coasts for growth.

Thanks to booming sales of blockbuster obesity and diabetes treatments, the amount that Americans spent on prescription drugs this year is on track to surpass $1 trillion. Total aggregate value of the drugs generating the highest sales in 2025 jumped 21.5% vs. 2024, and more than doubled from a decade ago.

Mid-cap buyers, improved capital raising climate, and reshoring of manufacturing are shaping how much and where biopharmas choose to grow.

What are the best-selling gene therapies on the market? It probably comes as no surprise that Luxturna, Casgevy, and Zolgensma are on the list. But what is number 1? Check out the list to find out.

Access the latest issue of GEN and browse the archive of back issues when you subscribe to our digital edition.

Wednesday’s episode of GEN Live will explore the rapidly evolving field of AAV gene therapy. Leaders from clinical and translational research will discuss current advances and challenges in AAV vector development, delivery, safety, and long-term therapeutic efficacy.

The Perelman School of Medicine

University of Pennsylvania

Director, Clinical In Vivo Gene Therapy

Children’s Hospital of Philadelphia

Co-Director, Gene Therapy Program

Director, Viral Vector Facility

University of Texas Southwestern Medical Center

Touching Base is the dynamic podcast series from the editors of GEN. Each episode features a rotating case of senior editors—including John Sterling, Kevin Davies, Julianna LeMieux, Alex Phillippidis, Uduak Thomas, Corinna Singleman, and Fay Lin—who delve into emerging stories, exchange ideas, and debate the latest trends in biotech. Additionally, they talk to some of the leading voices in the industry about what’s now and next. Start listening today!

Stay up to date with the lasted episodes of Touching Base by subscribing to the GEN Podcast Newsletter

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Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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