Educational guide
GLP-1 Microdosing Program
SERVICE Learn about our medically managed, 12-week GLP-1 microdosing program. This program is recommended for patients who need anti-inflammatory or modest body composition changes. What is microdosing? Microdosing is using 1/5 of a weight loss dose of a GLP-1
This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.
SERVICE
Learn about our medically managed, 12-week GLP-1 microdosing program. This program is recommended for patients who need anti-inflammatory or modest body composition changes.
What is
microdosing?
Microdosing is using 1/5 of a weight loss dose of a GLP-1 to achieve various benefits, while reducing side effects.
Benefits May Include
- Reduced Inflammation: May lower systemic inflammation, which is at the root of heart disease, joint pain, and immune dysfunction.
- Improved blood sugar control: Stabilizes blood sugar even in non-diabetics, reducing cravings, boosting energy, and slowing inflammation-related aging.
- Enhanced insulin sensitivity: Helps the body process glucose more efficiently, reducing the risk of metabolic syndrome and supporting muscle mass.
- Cardiovascular protection: Lowers blood pressure, LDL cholesterol, and triglycerides, and reduces the risk of cardiovascular events.
- Support for liver health: Reduces liver fat and improves fat metabolism, protecting against non-alcoholic fatty liver disease.
- Cognitive benefits: Emerging research suggests neuroprotective effects that may support mental clarity, memory, and focus.
- Reduced cravings: Many patients report lower cravings for alcohol, tobacco, and other substances.
- Modest change in body composition: Some patients experience a very modest amount of weight loss. For weight loss above 10 pounds, our Holistic Medical Weight Optimization Program is the better fit.
What to expect on your
three-month GLP-1 microdosing journey
- Step One If you are a new patient and you have not previously had a dedicated hormone optimization consult, we will schedule that first (prior to scheduling your first consultation) since hormone balance is foundational to success.
- Step Two Initial 30-minute consultation with a nurse practitioner. We will teach you to inject the medication and give you a vial for weekly use at home.
- Step Three 30-minute virtual or in-person check in every four weeks for 3 visits – includes body composition, review of nutrition, movement, medications and supplements.
- Step Four If your journey continues past 12 weeks, 30-minute check-ins monthly as needed until we reach your goal.
GLP-1 & Inflammation
Tiny doses. Big Potential.
Evidence
Currently, evidence for microdosing is observational and emerging. There is 1 trial underway that is actively studying the effectiveness of microdosed GLP‑1 receptor agonists for improving health and quality of life. ClinicalTrials.gov (NCT07092605, July 30, 2025)
Here are a few trials that support use of GLP-1’s for other than diabetes and weight loss. The doses used were standard doses.
- Cardiovascular and kidney-LEADER, Sustain-6, REWIND, SELECT, FLOW
- Cognitive-Wang 2024, Gejl 2016, Athauda 2017
- Inflammation-Ren 2025, Mason 2024
- Liver-Arun 2025, Newsome 2021
Begin your journey
Weight gain in midlife
isn’t just a fact of life.
Let our team help you feel your best now and through your midlife years. Book a consultation and put yourself first.