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Glow Recipe Guava Vitamin C Dark Spot Treatment Serum Versus Biossance Squalane + Phyto-Retinol Serum

Glow Recipe Guava Vitamin C Dark Spot Treatment Serum Versus Biossance Squalane + Phyto-Retinol Serum This brightening serum is formulated around Tetrahexyldecyl Ascorbate and Tranexamic Acid to fade the look of dark spots and brighten dull-looking skin. This

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

Glow Recipe Guava Vitamin C Dark Spot Treatment Serum Versus Biossance Squalane + Phyto-Retinol Serum

This brightening serum is formulated around Tetrahexyldecyl Ascorbate and Tranexamic Acid to fade the look of dark spots and brighten dull-looking skin.

This anti-aging serum is formulated around Squalane and Niacinamide to soften the look of wrinkles and strengthen the skin barrier.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Propanediol

C9-12 Alkane

Psidium Guajava Fruit Extract

Tetrahexyldecyl Ascorbate

Tranexamic Acid

Sodium Polyacryloyldimethyl Taurate

3-O-Ethyl Ascorbic Acid

Ascorbyl Glucoside

Magnesium Ascorbyl Phosphate

Sodium Ascorbyl Phosphate

Psidium Guajava Seed Oil

Tocopherol

Tocopheryl Acetate

Sodium Hyaluronate

Ferulic Acid

Tremella Fuciformis Sporocarp Extract

Pyrus Malus Fruit Extract

Musa Sapientum Fruit Extract

Prunus Armeniaca Kernel Extract

Pyrus Communis Fruit Extract

Rubus Idaeus Fruit Extract

Melia Azadirachta Flower Extract

Melia Azadirachta Leaf Extract

Corallina Officinalis Extract

Coccinia Indica Fruit Extract

Hexanoyl Dipeptide-3 Norleucine Acetate

Polyglyceryl-10 Dioleate

Glycerin

1,2-Hexanediol

Caprylic/Capric Triglyceride

Caprylyl Glycol

Hydroxyacetophenone

Sodium Stearoyl Glutamate

Coco-Caprylate/Caprate

Betaine

Lecithin

Polyglyceryl-10 Dipalmitate

Sodium Citrate

Sodium Phytate

Potassium Sorbate

Decyl Glucoside

Lauryl Glucoside

Ethylhexylglycerin

Citric Acid

Xanthan Gum

Phenoxyethanol

Water, Propanediol, C9-12 Alkane, Psidium Guajava Fruit Extract, Tetrahexyldecyl Ascorbate, Tranexamic Acid, Sodium Polyacryloyldimethyl Taurate, 3-O-Ethyl Ascorbic Acid, Ascorbyl Glucoside, Magnesium Ascorbyl Phosphate, Sodium Ascorbyl Phosphate, Psidium Guajava Seed Oil, Tocopherol, Tocopheryl Acetate, Sodium Hyaluronate, Ferulic Acid, Tremella Fuciformis Sporocarp Extract, Pyrus Malus Fruit Extract, Musa Sapientum Fruit Extract, Prunus Armeniaca Kernel Extract, Pyrus Communis Fruit Extract, Rubus Idaeus Fruit Extract, Melia Azadirachta Flower Extract, Melia Azadirachta Leaf Extract, Corallina Officinalis Extract, Coccinia Indica Fruit Extract, Hexanoyl Dipeptide-3 Norleucine Acetate, Polyglyceryl-10 Dioleate, Glycerin, 1,2-Hexanediol, Caprylic/Capric Triglyceride, Caprylyl Glycol, Hydroxyacetophenone, Sodium Stearoyl Glutamate, Coco-Caprylate/Caprate, Betaine, Lecithin, Polyglyceryl-10 Dipalmitate, Sodium Citrate, Sodium Phytate, Potassium Sorbate, Decyl Glucoside, Lauryl Glucoside, Ethylhexylglycerin, Citric Acid, Xanthan Gum, Phenoxyethanol

Squalane

Niacinamide

Sodium Acrylates Copolymer

Bakuchiol

Rosa Canina Fruit Oil

Citrus Aurantium Amara Peel Oil

Biosaccharide Gum-1

Yeast Extract

Soy Amino Acids

Hexylene Glycol

Tetrasodium Glutamate Diacetate

Linalool

Geraniol

Limonene

Water, Squalane, Niacinamide, Sodium Acrylates Copolymer, Bakuchiol, Sodium Hyaluronate, Rosa Canina Fruit Oil, Citrus Aurantium Amara Peel Oil, Biosaccharide Gum-1, Yeast Extract, Soy Amino Acids, Lecithin, Hexylene Glycol, Ethylhexylglycerin, Caprylyl Glycol, Phenoxyethanol, Tetrasodium Glutamate Diacetate, Citric Acid, Linalool, Geraniol, Limonene

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.

Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.

However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.

Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.

In skincare formulas, citric acid can:

While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.

Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.

Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.

However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's skin is unique, we recommend a patch test if you are unsure.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of phospholipids.

Thanks to its amphiphilic structure (water-loving head and oil-loving tail), it is a true multitasker:

It plays well with most ingredients and is typically used at 0.1-1%. However, concentrations up to 50% have been reported in moisturizers.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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