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GLAMGLOW BRIGHTEYES™ Illuminating Anti-Fatigue Eye Cream Versus Estée Lauder Advanced Night Repair Eye Concentrate Matrix Synchronized Recovery Complex

GLAMGLOW BRIGHTEYES™ Illuminating Anti-Fatigue Eye Cream Versus Estée Lauder Advanced Night Repair Eye Concentrate Matrix Synchronized Recovery Complex This brightening eye moisturizer is formulated around Caffeine and Aminopropyl Ascorbyl Phosphate to brighte

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

GLAMGLOW BRIGHTEYES™ Illuminating Anti-Fatigue Eye Cream Versus Estée Lauder Advanced Night Repair Eye Concentrate Matrix Synchronized Recovery Complex

This brightening eye moisturizer is formulated around Caffeine and Aminopropyl Ascorbyl Phosphate to brighten dull-looking skin and soften the look of wrinkles.

This barrier-repair eye moisturizer is formulated around Bifida Ferment Lysate and Caffeine to strengthen the skin barrier and soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Butyrospermum Parkii Butter

Butylene Glycol

Dimethicone

Glycerin

Cetearyl Alcohol

Cetyl Esters

Isostearyl Neopentanoate

Cetyl Alcohol

Polybutene

Sodium Hyaluronate

Caffeine

Tocopheryl Acetate

Narcissus Tazetta Bulb Extract

Aminopropyl Ascorbyl Phosphate

Linoleic Acid

Acetyl Hexapeptide-8

Artemia Extract

Hibiscus Sabdariffa Flower Extract

Trifluoroacetyl Tripeptide-2

Anthemis Nobilis Flower Extract

Laminaria Digitata Extract

Cucumis Melo Fruit Extract

Cetearyl Glucoside

Cholesterol

Persea Gratissima Oil

Pyrus Malus Fruit Extract

Lens Esculenta Fruit Extract

Citrullus Lanatus Fruit Extract

Algae Extract

Lauryl PCA

Whey Protein

Faex Extract

Sodium Lactate

Sorbitol

Trehalose

Zinc PCA

Glucose

Acetyl Glucosamine

Neopentyl Glycol Diheptanoate

Carbomer

Sodium Hydroxide

Propylene Glycol Dicaprylate

Polymethyl Methacrylate

Sodium PCA

Dextran

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Polyethylene

Decarboxy Carnosine Hcl

Potassium Sulfate

Caprylyl Glycol

1,2-Hexanediol

Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate

Methyl Glucose Sesquistearate

BHT

Disodium EDTA

Phenoxyethanol

Potassium Sorbate

Sodium Benzoate

Mica

CI 77891

CI 77491

Water, Butyrospermum Parkii Butter, Butylene Glycol, Dimethicone, Glycerin, Cetearyl Alcohol, Cetyl Esters, Isostearyl Neopentanoate, Cetyl Alcohol, Polybutene, Sodium Hyaluronate, Caffeine, Tocopheryl Acetate, Narcissus Tazetta Bulb Extract, Aminopropyl Ascorbyl Phosphate, Linoleic Acid, Acetyl Hexapeptide-8, Artemia Extract, Hibiscus Sabdariffa Flower Extract, Trifluoroacetyl Tripeptide-2, Anthemis Nobilis Flower Extract, Laminaria Digitata Extract, Cucumis Melo Fruit Extract, Cetearyl Glucoside, Cholesterol, Persea Gratissima Oil, Pyrus Malus Fruit Extract, Lens Esculenta Fruit Extract, Citrullus Lanatus Fruit Extract, Algae Extract, Lauryl PCA, Whey Protein, Faex Extract, Sodium Lactate, Sorbitol, Trehalose, Zinc PCA, Glucose, Acetyl Glucosamine, Neopentyl Glycol Diheptanoate, Carbomer, Sodium Hydroxide, Propylene Glycol Dicaprylate, Polymethyl Methacrylate, Sodium PCA, Dextran, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Polyethylene, Decarboxy Carnosine Hcl, Potassium Sulfate, Caprylyl Glycol, 1,2-Hexanediol, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Methyl Glucose Sesquistearate, BHT, Disodium EDTA, Phenoxyethanol, Potassium Sorbate, Sodium Benzoate, Mica, CI 77891, CI 77491

Bifida Ferment Lysate

Isohexadecane

Bis-PEG-18 Methyl Ether Dimethyl Silane

PEG-10 Dimethicone

Disteardimonium Hectorite

Isopropyl Isostearate

PPG-15 Stearyl Ether

Sucrose

Adansonia Digitata Seed Extract

Tripeptide-32

Lactobacillus Ferment

Sodium Rna

Hydrolyzed Algin

Hydroxyethyl Urea

Cucumis Sativus Fruit Extract

Hordeum Vulgare Extract

Silybum Marianum Extract

Glycine Soja Seed Extract

Camelina Sativa Seed Oil

Betula Alba Bark Extract

Scutellaria Baicalensis Root Extract

Morus Bombycis Root Extract

Poria Cocos Sclerotium Extract

Propylene Glycol Dicaprate

Sodium Polyaspartate

Hydrogenated Lecithin

Phytosphingosine

Ethylhexylglycerin

Polysilicone-11

Isododecane

Helianthus Annuus Seed Extract

Propylene Carbonate

Polyacrylate Crosspolymer-6

Lecithin

Fructose

T-Butyl Alcohol

Hydroxyacetophenone

Sodium Dehydroacetate

Water, Dimethicone, Bifida Ferment Lysate, Isohexadecane, Glycerin, Butylene Glycol, Bis-PEG-18 Methyl Ether Dimethyl Silane, PEG-10 Dimethicone, Disteardimonium Hectorite, Isopropyl Isostearate, PPG-15 Stearyl Ether, Sucrose, Trehalose, Adansonia Digitata Seed Extract, Tripeptide-32, Faex Extract, Sodium Hyaluronate, Lactobacillus Ferment, Algae Extract, Sodium Rna, Hydrolyzed Algin, Caffeine, Hydroxyethyl Urea, Aminopropyl Ascorbyl Phosphate, Cucumis Sativus Fruit Extract, Anthemis Nobilis Flower Extract, Hordeum Vulgare Extract, Silybum Marianum Extract, Glycine Soja Seed Extract, Camelina Sativa Seed Oil, Sorbitol, Betula Alba Bark Extract, Scutellaria Baicalensis Root Extract, Morus Bombycis Root Extract, Poria Cocos Sclerotium Extract, Tocopheryl Acetate, Propylene Glycol Dicaprate, Sodium Polyaspartate, Hydrogenated Lecithin, Phytosphingosine, Ethylhexylglycerin, Polysilicone-11, Isododecane, Helianthus Annuus Seed Extract, Polyethylene, Propylene Carbonate, Polyacrylate Crosspolymer-6, Lecithin, Glucose, Fructose, T-Butyl Alcohol, Disodium EDTA, BHT, Hydroxyacetophenone, Sodium Dehydroacetate, Potassium Sorbate, Phenoxyethanol, CI 77491

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Algae Extract is a confusing name. This is because algae is an informal term for a group of 30,000 aquatic organisms that can photosynthesize.

The term 'algae extract' can refer to any one, or a blend of, the 30,000 types.

Algae is rich in antioxidants. Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells, such as pollution.

Algae can also help with soothing and hydrating skin.

Many different types of algae have different benefits.

Aminopropyl Ascorbyl Phosphate (AAP) is a form of Vitamin C. AAP was made as a more stable alternative to Ascorbic Acid by combining Ascorbic Acid (pure Vitamin C) with 3-aminoproply dehydrogen phosphate.

As a type of Vitamin C, it has antioxidant properties. Antioxidants help fight free-radical molecules, or molecules that may damage your skin cells.

AAP has been shown to help reduce signs of hyperigmentation and age-spots.

AAP is water soluble.

Vitamin C can help to reduce redness, improve skin texture, reduce the effects of aging, and reduce the visibility of dark spots.

Read more about other types of Vitamin C:

Anthemis Nobilis Flower Extract is from the Roman Chamomile flower. It helps soothe the skin and contains antioxidants.

BHT is a synthetic antioxidant and preservative.

As an antioxidant, it helps your body fight off free-radicals. Free-radicals are molecules that may damage your skin cells.

As a preservative, it is used to stabilize products and prevent them from degrading. Specifically, BHT prevents degradation from oxidation.

The concerns related to BHT come from oral studies; this ingredient is currently allowed for use by both the FDA and EU.

However, it was recently restricted for use in the UK as of April 2024.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Caffeine is a naturally occurring plant compound found in coffee beans, tea leaves, cocoa pods, and guarana.

As an antioxidant, caffeine protects your skin from free radical damage caused by UV exposure and envionrmnetal stressors.

Early research also shows that caffeine can help calm redness, soothe irritated skin, and support hair growth by stimulating microcirculation in the scalp.

You might have seen eye creams marketing caffeine as a depuffing ingredient. This is because it is a vasoconstrictor meaning it can temporarily constrict blood vessels, though clinical evidence for this specific use is still limited.

Most skincare products contain this ingredient at concentrations between 1-6%. It is able to penetrate skin easily regardless of skin type or thickness.

Just so you know, a very small number of case reports describe caffeine-induced allergy. This ingredient is generally well-tolerated, non-irritating, and non-sensitizing for the majority of people.

Ci 77491 is also hydrated iron III oxide. It's sole purpose is to give a red/pink hue to products.

Iron III oxides are classified as inorganic chemicals for coloring.

Synthetically created Ci 77491 is considered safer than those naturally found. This is because the synthetically created version may contain less impurities. Iron oxides are generally non-toxic and non-allergenic.

Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.

What it does:

Dimethicone comes in different viscosities:

Depending on the viscosity, dimethicone has different properties.

Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.

This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.

Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.

Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.

This ingredient mainly works behind the scenes and helps with:

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

We don't have a description for Faex Extract yet.

Glucose is a simple sugar (a monosaccharide). In skincare, it is mostly a humectant and skin conditioning agent.

Mechanistically, it has multiple hydroxyl groups that hydrogen-bond to water. This pulls moisture into the upper layers of skin to keep the surface soft and hydrated.

It's worth knowing sugars are already a natural component of the skin's NMF (natural moisturizing factor) so it's a molecule that your stratum corneum is well-acquainted with.

Just so you know, glucose is hydrophilic (water-loving) and the stratum corneum is a strong barrier to hydrophilic compounds. This just means penetration is slow and most of the action is happening on the surface.

Gram-to-gram, glucose is not as efficient as a humectant as glycerin. This is why you'll likely see glycose paired with stronger humectants for a bigger hydration payoff.

In skincare, glucose is typically derived from corn or other starch sources.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Polyethylene is a synthetic ingredient that helps the skin retain moisture. It is a polymer.

It is also typically used within product formulations to help bind solid ingredients together and thicken oil-based ingredients. When added to balms and emulsions, it helps increase the melting point temperature.

Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.

This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.

Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.

You'll often find this ingredient used with other preservatives.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Sorbitol is a sugar alcohol. It is a hydrating and moisturizing agent created from the reduction process of glucose.

Most sorbitol is usually made from potato starch. It is also found in fruits such as apples and pears.

As a humectant, Sorbitol helps draw water to the skin. This helps keep the skin hydrated. Sorbitol also helps create a thicker texture in products. You might find sorbitol in your toothpaste and other gels.

It is a non-irritating ingredient that is great for those with dry skin.

Sorbitol is a prebiotic. It helps promote the growth of healthy bacteria on your skin. The bacteria on your skin form a microbiome. This microbiome helps protect your skin from infection and harmful bacteria.

Tocopheryl Acetate is a stable, shelf-friendly form of vitamin E.

Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.

It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.

One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.

Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.

Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.

The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.

Most leave-on skincare keeps it at the lower end, often between 0.5-1%.

Trehalose is a disaccharide made of two glucose molecules (glucose is sugar!). Trehalose is used to help moisturize skin. It also has antioxidant properties.

As a humectant, trehalose helps draw moisture from the air to your skin. This helps keep your skin hydrated.

Due to its antioxidant properties, trehalose may help with signs of aging. Antioxidants help fight free-radical molecules, unstable molecules that may damage your skin.

In medicine, trehalose and hyaluronic acid are used to help treat dry eyes.

Some animals, plants, and bacteria create trehalose as a source of energy to survive freeze or lack of water.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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About the author

Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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