Educational guide
Gattex: Uses, Side Effects & Dosage | Healio
Topics Gattex Brand Names Gattex Generic Name teduglutide Phonetic Name (TE-due-GLOO-tide) Clinical Uses Teduglutide is used by patients with Short Bowel Syndrome (SBS) who need intravenous (IV) nutrition and fluids. It may help to decrease the amount of intra
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Topics
Gattex
Brand Names
Gattex
Generic Name
teduglutide
Phonetic Name
(TE-due-GLOO-tide)
Clinical Uses
Teduglutide is used by patients with Short Bowel Syndrome (SBS) who need intravenous (IV) nutrition and fluids. It may help to decrease the amount of intravenous nutrition needed by the patient. Teduglutide is similar to a natural hormone in your body (GLP-2). It works by helping to improve intestinal absorption of fluids and nutrients.
Dosage and Administration
Administration Notes
Read the Medication Guide and the Instructions For Use provided by your pharmacist before you start using teduglutide and each time you get a refill. Ask your health care professional how to prepare and use this medication. If you have any questions, ask your doctor or pharmacist. Inject this medication under the skin as directed by your doctor, usually once daily. The injection is given in the thigh, abdomen, or upper arm. The dosage is based on your medical condition, weight, and response to treatment. Do not shake the vial. Before using, check this product for particles or discoloration. If either is present, do not use the liquid. Before injecting each dose, clean the skin you are going to inject into (the injection site) with rubbing alcohol. Change the injection site each time to lessen injury under the skin. To lessen bruising, do not rub the injection site after a shot. Learn how to store and discard medical supplies safely. Use this medication regularly to get the most benefit from it. To help you remember, use it at the same time each day.
Missed Dose Instructions
If you miss a dose, use it as soon as you remember. If you don't remember until the next day, skip the missed dose. Use your next dose at the regular time. Do not double the dose or use 2 doses on the same day to catch up.
Label Warnings
Roll gently in your hands to mix well before each injection. Do not shake Warning: Breastfeeding is not recommended while using this drug. Consult your doctor or pharmacist. Discard unused portion after _________ hours. Discard any remaining product after using. Do not keep or store for future use. Store at room temperature.
Indications
- short bowel syndrome
Teduglutide is used by patients with Short Bowel Syndrome (SBS) who need intravenous (IV) nutrition and fluids. It may help to decrease the amount of intravenous nutrition needed by the patient. Teduglutide is similar to a natural hormone in your body (GLP-2). It works by helping to improve intestinal absorption of fluids and nutrients.
Contraindications
- biliary tract malignancy
- lactation
- malignant neoplasm of pancreas
- primary malignant neoplasm of gastrointestinal tract
- biliary calculus
- cholangitis
- cholecystitis
- chronic kidney disease stage 3A (moderate) GFR 45-59 mL/min
- chronic kidney disease stage 3B (moderate) GFR 30-44 mL/min
- chronic kidney disease stage 4 (severe) GFR 15-29 mL/min
- chronic kidney disease stage 5 (failure) GFR<15 mL/min
- colorectal polyp
- edema
- elevated serum amylase
- elevated serum lipase
- gastrointestinal obstruction
- malignancy
- polyp of intestine
- chronic heart failure
- hyperbilirubinemia
- kidney disease with likely reduction in glomerular filtration rate (GFR)
Common Adverse Effects
- Abdominal distension
- Acute abdominal pain
- Body fluid retention
- Headache disorder
- Hypervolemia
- Injection site sequelae
- Nausea
- Upper respiratory infection
- Vomiting
- Appetite changes
- Cough
- Flatulence
- Hemorrhage
- Sleep disorder
- Dyspnea
Serious Adverse Effects
- Hypersensitivity drug reaction
- Biliary calculus
- Cardiac arrest
- Cholangitis
- Cholecystitis
- Chronic heart failure
- Colorectal polyp
- Gastrointestinal obstruction
- Intestinal stenosis
- Malignancy
- Neoplasm
- Pancreatic duct stenosis
- Pancreatitis
- Polyp of intestine
Elderly Precautions
Pregnancy Precautions
Lactation Precautions
Pediatric Precautions
Drug Interactions
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
Storage Requirements
Store the unmixed medication at room temperature. Do not freeze. After mixing, use the mixed medication within 3 hours and discard any unused portion. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of your healthcare professional. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you. You should consult your healthcare professional before taking any drug, changing your diet or commencing or discontinuing any course of treatment. See our full terms of use.
This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking any drug or commencing or discontinuing any course of treatment.