Educational guide
Estée Lauder Advanced Night Repair Synchronized Recovery Complex II Versus Filorga NCEF-Intensive Supreme Multi-Correction Serum
Estée Lauder Advanced Night Repair Synchronized Recovery Complex II Versus Filorga NCEF-Intensive Supreme Multi-Correction Serum This barrier-repair serum is formulated around Bifida Ferment Lysate to strengthen the skin barrier. This anti-aging serum is formu
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Estée Lauder Advanced Night Repair Synchronized Recovery Complex II Versus Filorga NCEF-Intensive Supreme Multi-Correction Serum
This barrier-repair serum is formulated around Bifida Ferment Lysate to strengthen the skin barrier.
This anti-aging serum is formulated around Gluconolactone and Niacinamide to soften the look of wrinkles and refine skin texture.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Bifida Ferment Lysate
Methyl Gluceth-20
PEG-75
Bis-PEG-18 Methyl Ether Dimethyl Silane
Butylene Glycol
Propanediol
Cola Acuminata Seed Extract
Hydrolyzed Algin
Pantethine
Caffeine
Lecithin
Tripeptide-32
Ethylhexylglycerin
Sodium Rna
Bisabolol
Glycereth-26
Squalane
Sodium Hyaluronate
Oleth-3 Phosphate
Caprylyl Glycol
Lactobacillus Ferment
Oleth-3
Oleth-5
Anthemis Nobilis Flower Extract
Faex Extract
Choleth-24
Hydrogenated Lecithin
Ceteth-24
Tocopheryl Acetate
Ethylhexyl Methoxycinnamate
Hexylene Glycol
Carbomer
Triethanolamine
Trisodium EDTA
BHT
Xanthan Gum
Phenoxyethanol
CI 14700
CI 19140
Water, Bifida Ferment Lysate, Methyl Gluceth-20, PEG-75, Bis-PEG-18 Methyl Ether Dimethyl Silane, Butylene Glycol, Propanediol, Cola Acuminata Seed Extract, Hydrolyzed Algin, Pantethine, Caffeine, Lecithin, Tripeptide-32, Ethylhexylglycerin, Sodium Rna, Bisabolol, Glycereth-26, Squalane, Sodium Hyaluronate, Oleth-3 Phosphate, Caprylyl Glycol, Lactobacillus Ferment, Oleth-3, Oleth-5, Anthemis Nobilis Flower Extract, Faex Extract, Choleth-24, Hydrogenated Lecithin, Ceteth-24, Tocopheryl Acetate, Ethylhexyl Methoxycinnamate, Hexylene Glycol, Carbomer, Triethanolamine, Trisodium EDTA, BHT, Xanthan Gum, Phenoxyethanol, CI 14700, CI 19140
C10-18 Triglycerides
Caprylic/Capric Triglyceride
Heptyl Undecylenate
Glycerin
Ethylhexyl Palmitate
Glyceryl Stearate
PEG-100 Stearate
Sodium Citrate
Maltodextrin
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Arginine PCA
Cetyl Alcohol
Gluconolactone
Hydrogenated Olive Oil Stearyl Esters
Mannitol
Parfum
Sucrose Dilaurate
Maris Aqua
Simmondsia Chinensis Seed Oil
Tribehenin
Sucrose Palmitate
Hydroxyacetophenone
Citric Acid
Sodium Hydroxide
Polyacrylate Crosspolymer-6
Sodium Cocoyl Glutamate
Tocopherol
Helianthus Annuus Seed Oil
Lysolecithin
Glyceryl Linoleate
Paeonia Albiflora Root Extract
Prunus Amygdalus Dulcis Oil
Pisum Sativum Extract
Polysorbate 60
Sorbitan Isostearate
Sodium Chloride
Borago Officinalis Seed Oil
Oenothera Biennis Oil
Camellia Oleifera Seed Oil
CI 77891
Synthetic Fluorphlogopite
Trihydroxystearin
Niacinamide
3-O-Ethyl Ascorbic Acid
Potassium Azeloyl Diglycinate
Sodium Phytate
Ceramide NP
1,2-Hexanediol
Glucose
Potassium Chloride
Beta-Sitosterol
Phytic Acid
Squalene
Potassium Sorbate
Calcium Chloride
Sophora Japonica Flower Extract
Acetyl Tetrapeptide-11
Magnesium Sulfate
Glutamine
Acetyl Tetrapeptide-9
Tin Oxide
Sodium Phosphate
Ascorbic Acid
Sodium Acetate
Lysine Hcl
Arginine Hcl
Alanine
CI 17200
Histidine Hcl
Valine
Leucine
Threonine
Isoleucine
Tryptophan
Phenylalanine
Tyrosine
Glycine
Polysorbate 80
Glucomannan
Serine
Cystine
Cyanocobalamin
Glutathione
Asparagine
Aspartic Acid
Ornithine Hcl
Glutamic Acid
Nicotinamide Adenine Dinucleotide
Proline
Methionine
Taurine
Hydroxyproline
Glucosamine Hcl
Coenzyme A
Sodium Glucuronate
Thiamine Diphosphate
Retinyl Acetate
Inositol
Niacin
Pyridoxine Hcl
Biotin
Calcium Pantothenate
Riboflavin
Sodium Tocopheryl Phosphate
Thiamine Hcl
Folic Acid
Water, C10-18 Triglycerides, Caprylic/Capric Triglyceride, Heptyl Undecylenate, Glycerin, Propanediol, Ethylhexyl Palmitate, Glyceryl Stearate, PEG-100 Stearate, Butylene Glycol, Sodium Citrate, Maltodextrin, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Arginine PCA, Cetyl Alcohol, Gluconolactone, Hydrogenated Olive Oil Stearyl Esters, Mannitol, Parfum, Sucrose Dilaurate, Maris Aqua, Simmondsia Chinensis Seed Oil, Tribehenin, Sucrose Palmitate, Hydroxyacetophenone, Caprylyl Glycol, Citric Acid, Sodium Hydroxide, Polyacrylate Crosspolymer-6, Sodium Cocoyl Glutamate, Tocopherol, Helianthus Annuus Seed Oil, Lecithin, Lysolecithin, Glyceryl Linoleate, Paeonia Albiflora Root Extract, Prunus Amygdalus Dulcis Oil, Pisum Sativum Extract, Polysorbate 60, Sorbitan Isostearate, Sodium Chloride, Borago Officinalis Seed Oil, Oenothera Biennis Oil, Camellia Oleifera Seed Oil, CI 77891, Synthetic Fluorphlogopite, Trihydroxystearin, Niacinamide, 3-O-Ethyl Ascorbic Acid, Lactobacillus Ferment, Potassium Azeloyl Diglycinate, Sodium Phytate, Ceramide NP, Sodium Hyaluronate, 1,2-Hexanediol, Glucose, Phenoxyethanol, Bisabolol, Potassium Chloride, Beta-Sitosterol, Phytic Acid, Squalene, Potassium Sorbate, Calcium Chloride, Sophora Japonica Flower Extract, Acetyl Tetrapeptide-11, Magnesium Sulfate, Glutamine, Acetyl Tetrapeptide-9, Tin Oxide, CI 19140, Sodium Phosphate, Ascorbic Acid, Sodium Acetate, Lysine Hcl, Arginine Hcl, Alanine, CI 17200, Histidine Hcl, Valine, Leucine, Threonine, Isoleucine, Tryptophan, Phenylalanine, Tyrosine, Glycine, Polysorbate 80, Glucomannan, Serine, Cystine, Cyanocobalamin, Glutathione, Asparagine, Aspartic Acid, Ornithine Hcl, Glutamic Acid, Nicotinamide Adenine Dinucleotide, Proline, Methionine, Taurine, Hydroxyproline, Glucosamine Hcl, Coenzyme A, Sodium Glucuronate, Thiamine Diphosphate, Retinyl Acetate, Inositol, Niacin, Pyridoxine Hcl, Biotin, Calcium Pantothenate, Riboflavin, Sodium Tocopheryl Phosphate, Thiamine Hcl, Folic Acid
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Bisabolol is a gentle skin conditioner, antioxidant, and soothing ingredient.
It's primary claim to fame is soothing and research shows topically applied bisabolol can quiet the chemical messengers that cause your skin to become inflamed, helping to sooth any irritation.
A clinical study found that applying 0.5% bisabolol daily for 8 weeks produced an average 9% decrease in skin pigmentation. Researchers found it can also suppress the process that leads to excess melanin production in skin.
In vitro studies found that bisabolol combined with propylene glycol significantly increased skin permeability by increasing lipid fluidity in the stratum corneum.
You'll likely see use concentrations quite low, usually 0.1-0.2%.
Overall, this is a well-tolerated ingredient that works well in formulas designed for sensitive, reactive, or post-procedure skin.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
CI 19140 is also known as Tartrazine. Tartrazine is a synthetic dye used in cosmetics, foods, and medicine to add a yellow color.
Tartrazine is created from petroleum and is water-soluble.
Some people may experience allergies from this dye, especially asthmatics and those with an aspirin intolerance.
This ingredient is made when the Lactobacillus bacteria (the same kind that makes yogurt and kimchi) are allowed to ferment a nutrient medium.
As it ferments, it collects lactic acid, peptides, enzymes, and other bioactive metabolites to provide:
A 2023 review noted that probiotic fermentation ingredients like this one can enhance antioxidant capacity, reduce UV-induced oxidative damage, and support barrier function.
One clinical study from the same year showed a Lactobacillus ferment lysate significantly reduced transepidermal water loss and improved skin hydration.
Another review highlighted that topical Lactobacillus-based preparations can improve ceramide levels in the stratum corneum, support barrier integrity, and even help reduce S. aureus colonization in atopic dermatitis.
Why is this so cool?
Basically, your skin's outer layer works as a brick wall; skin cells are bricks and ceramides are the mortar holding it together. Moisture escapes, irritants get in, and your skin gets dry and reactive when ceramide levels drop. On top of that, "bad" skin bacteria S. aureus loves to move in when your barrier is weak to make inflammation and irritation worse.
So Lactobacillus ferment is basically patching the wall and evicting the troublemaker when it boosts ceramide production and help keep S. aureus in check.
On top of all this, it also acts as a mild antimicrobial preservative booster.
Just so you know, most studies focus on specific strains or the lysate form rather than this generic "Lactobacillus Ferment", so results can vary.
Though it's a promising ingredient, it doesn't have decades of robust clinical data behind it just yet.
Lactobacillus Ferment is generally considered safe for fungal-acne prone skin. The key thing to understand is that it comes from bacteria, not yeast or fungus.
Yeast-derived ferments (like galactomyces) have been shown to activate a protein that's linked to Malassezia-related skin issues whereas lactobacillus doesn't have that problem.
Its byproducts also don't contain the types of fatty acids (C11-24 chain lengths) that Malassezia feeds on.
Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of phospholipids.
Thanks to its amphiphilic structure (water-loving head and oil-loving tail), it is a true multitasker:
It plays well with most ingredients and is typically used at 0.1-1%. However, concentrations up to 50% have been reported in moisturizers.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!