Educational guide
Estée Lauder Advanced Night Repair Rescue Solution Serum With 15% Bifidus Ferment Versus Revolution Beauty Pro Miracle Night Rescue Serum Advanced Complex
Estée Lauder Advanced Night Repair Rescue Solution Serum With 15% Bifidus Ferment Versus Revolution Beauty Pro Miracle Night Rescue Serum Advanced Complex This calming serum is formulated around Bifida Ferment Filtrate and Resveratrol to calm redness and stren
This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.
Estée Lauder Advanced Night Repair Rescue Solution Serum With 15% Bifidus Ferment Versus Revolution Beauty Pro Miracle Night Rescue Serum Advanced Complex
This calming serum is formulated around Bifida Ferment Filtrate and Resveratrol to calm redness and strengthen the skin barrier.
This barrier-repair serum is formulated around Lactobacillus Ferment Lysate and Bifida Ferment Lysate to strengthen the skin barrier and calm redness.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Bifida Ferment Filtrate
PEG-8
Butylene Glycol
Glycerin
Polysorbate 80
Bis-PEG-18 Methyl Ether Dimethyl Silane
Tripeptide-32
Hydrolyzed Yeast Protein
Lactobacillus Ferment
Sodium Hyaluronate
Caffeine
Hypnea Musciformis Extract
Citrullus Lanatus Fruit Extract
Lens Esculenta Fruit Extract
Pyrus Malus Fruit Extract
Magnolia Officinalis Bark Extract
Resveratrol
Poria Cocos Sclerotium Extract
Silybum Marianum Fruit Extract
Sapindus Mukorossi Fruit Extract
Anthemis Nobilis Flower Extract
Sodium Lactate
Ethylhexylglycerin
Potassium Gluconate
Sodium PCA
Caesalpinia Spinosa Gum
Sucrose
Caprylyl Glycol
Hexylene Glycol
Carbomer
Xanthan Gum
PPG-6-Decyltetradeceth-30
PPG-5-Ceteth-20
BHT
Disodium EDTA
Sodium Hydroxide
Potassium Sorbate
Phenoxyethanol
Sodium Benzoate
CI 14700
CI 19140
Water, Bifida Ferment Filtrate, PEG-8, Butylene Glycol, Glycerin, Polysorbate 80, Bis-PEG-18 Methyl Ether Dimethyl Silane, Tripeptide-32, Hydrolyzed Yeast Protein, Lactobacillus Ferment, Sodium Hyaluronate, Caffeine, Hypnea Musciformis Extract, Citrullus Lanatus Fruit Extract, Lens Esculenta Fruit Extract, Pyrus Malus Fruit Extract, Magnolia Officinalis Bark Extract, Resveratrol, Poria Cocos Sclerotium Extract, Silybum Marianum Fruit Extract, Sapindus Mukorossi Fruit Extract, Anthemis Nobilis Flower Extract, Sodium Lactate, Ethylhexylglycerin, Potassium Gluconate, Sodium PCA, Caesalpinia Spinosa Gum, Sucrose, Caprylyl Glycol, Hexylene Glycol, Carbomer, Xanthan Gum, PPG-6-Decyltetradeceth-30, PPG-5-Ceteth-20, BHT, Disodium EDTA, Sodium Hydroxide, Potassium Sorbate, Phenoxyethanol, Sodium Benzoate, CI 14700, CI 19140
Lactobacillus Ferment Lysate
Bifida Ferment Lysate
Propanediol
PEG-8 Caprylic/Capric Glycerides
Betaine
Glycereth-26
Methyl Gluceth-10
Propylene Glycol
Yeast Extract
Simmondsia Chinensis Seed Oil
Squalane
Lavandula Angustifolia Oil
Bisabolol
Adansonia Digitata Fruit Extract
Chamomilla Recutita Flower Extract
Lactic Acid
Centella Asiatica Leaf Extract
Leuconostoc/Radish Root Ferment Filtrate
Sodium Chloride
Acetic Acid
Rosa Centifolia Flower Extract
Ceramide NP
2,3-Butanediol
Bis(Tripeptide-1) Copper Acetate
Hydrogenated Lecithin
Sorbic Acid
Glyceryl Stearate
Ceramide AP
Ceramide As
Ceramide Ns
Cholesterol
Sodium Metabisulfite
Ceramide EOP
Farnesol
Citronellol
Geraniol
Linalool
CI 15985
CI 17200
Water, Bis-PEG-18 Methyl Ether Dimethyl Silane, Lactobacillus Ferment Lysate, Bifida Ferment Lysate, Propanediol, PEG-8 Caprylic/Capric Glycerides, Betaine, Glycereth-26, Methyl Gluceth-10, Phenoxyethanol, Glycerin, Carbomer, Caffeine, Propylene Glycol, Yeast Extract, Sodium Hydroxide, Ethylhexylglycerin, Disodium EDTA, Simmondsia Chinensis Seed Oil, Squalane, Lavandula Angustifolia Oil, Bisabolol, Sodium Hyaluronate, Adansonia Digitata Fruit Extract, Chamomilla Recutita Flower Extract, Lactic Acid, Centella Asiatica Leaf Extract, Leuconostoc/Radish Root Ferment Filtrate, Sodium Benzoate, Sodium Chloride, Potassium Sorbate, Acetic Acid, Rosa Centifolia Flower Extract, Ceramide NP, 2,3-Butanediol, Caprylyl Glycol, Bis(Tripeptide-1) Copper Acetate, Hydrogenated Lecithin, Sorbic Acid, Glyceryl Stearate, Ceramide AP, Ceramide As, Ceramide Ns, Cholesterol, Sodium Metabisulfite, Ceramide EOP, Farnesol, Citronellol, Geraniol, Linalool, CI 15985, CI 19140, CI 17200
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Bis-Peg-18 Methyl Ether Dimethyl Silane belongs to the siloxanes and silicones classes. It is synthetically created and has a waxy composition.
This ingredient is a humectant and emollient, meaning it helps hydrate the skin. Humectants draw moisture to your skin, while emollients prevent moisture from escaping.
Caffeine is a naturally occurring plant compound found in coffee beans, tea leaves, cocoa pods, and guarana.
As an antioxidant, caffeine protects your skin from free radical damage caused by UV exposure and envionrmnetal stressors.
Early research also shows that caffeine can help calm redness, soothe irritated skin, and support hair growth by stimulating microcirculation in the scalp.
You might have seen eye creams marketing caffeine as a depuffing ingredient. This is because it is a vasoconstrictor meaning it can temporarily constrict blood vessels, though clinical evidence for this specific use is still limited.
Most skincare products contain this ingredient at concentrations between 1-6%. It is able to penetrate skin easily regardless of skin type or thickness.
Just so you know, a very small number of case reports describe caffeine-induced allergy. This ingredient is generally well-tolerated, non-irritating, and non-sensitizing for the majority of people.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.
Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.
It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.
Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.
A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.
CI 19140 is also known as Tartrazine. Tartrazine is a synthetic dye used in cosmetics, foods, and medicine to add a yellow color.
Tartrazine is created from petroleum and is water-soluble.
Some people may experience allergies from this dye, especially asthmatics and those with an aspirin intolerance.
Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
This ingredient mainly works behind the scenes and helps with:
On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).
Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.
This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.
Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.
You'll often find this ingredient used with other preservatives.
Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.
Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.
Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.
It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.
Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.
We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!