Educational guide
Estée Lauder Advanced Night Repair Intense Reset Concentrate Versus La Roche-Posay Retinol B3 Serum
Estée Lauder Advanced Night Repair Intense Reset Concentrate Versus La Roche-Posay Retinol B3 Serum This calming serum is formulated around Lactobacillus Ferment and Resveratrol to calm redness and strengthen the skin barrier. This anti-aging serum is formulat
This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.
Estée Lauder Advanced Night Repair Intense Reset Concentrate Versus La Roche-Posay Retinol B3 Serum
This calming serum is formulated around Lactobacillus Ferment and Resveratrol to calm redness and strengthen the skin barrier.
This anti-aging serum is formulated around Niacinamide and Retinol to soften the look of wrinkles and fade the look of dark spots.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Dimethicone
Glycerin
Methyl Trimethicone
Bis-PEG-18 Methyl Ether Dimethyl Silane
Butylene Glycol
Isopropyl Isostearate
PPG-15 Stearyl Ether
PEG-10 Dimethicone
Faex Extract
Tripeptide-32
Sodium Hyaluronate Crosspolymer
Sodium Hyaluronate
Hydrolyzed Sodium Hyaluronate
Hydrolyzed Algin
Lactobacillus Ferment
Adansonia Digitata Seed Extract
Soy Amino Acids
Aminopropyl Ascorbyl Phosphate
Resveratrol
Algae Extract
Salicylic Acid
Ergothioneine
Tocopheryl Acetate
Whey Protein
Avena Sativa Kernel Extract
Citrullus Lanatus Fruit Extract
Laminaria Digitata Extract
Lens Esculenta Fruit Extract
Pyrus Malus Fruit Extract
Caffeine
Sodium PCA
Propylene Glycol Caprylate
Triticum Vulgare Germ Extract
Lavandula Angustifolia Oil
Hordeum Vulgare Extract
Anthemis Nobilis Flower Extract
Isohexadecane
Polysilicone-11
Methyldihydrojasmonate
Sodium Lactate
Disteardimonium Hectorite
Isododecane
Polyacrylate Crosspolymer-6
Squalane
Polyethylene
Propylene Carbonate
Pentylene Glycol
Disodium EDTA
BHT
Potassium Sorbate
Sodium Benzoate
Phenoxyethanol
Linalool
CI 14700
CI 19140
Water, Dimethicone, Glycerin, Methyl Trimethicone, Bis-PEG-18 Methyl Ether Dimethyl Silane, Butylene Glycol, Isopropyl Isostearate, PPG-15 Stearyl Ether, PEG-10 Dimethicone, Faex Extract, Tripeptide-32, Sodium Hyaluronate Crosspolymer, Sodium Hyaluronate, Hydrolyzed Sodium Hyaluronate, Hydrolyzed Algin, Lactobacillus Ferment, Adansonia Digitata Seed Extract, Soy Amino Acids, Aminopropyl Ascorbyl Phosphate, Resveratrol, Algae Extract, Salicylic Acid, Ergothioneine, Tocopheryl Acetate, Whey Protein, Avena Sativa Kernel Extract, Citrullus Lanatus Fruit Extract, Laminaria Digitata Extract, Lens Esculenta Fruit Extract, Pyrus Malus Fruit Extract, Caffeine, Sodium PCA, Propylene Glycol Caprylate, Triticum Vulgare Germ Extract, Lavandula Angustifolia Oil, Hordeum Vulgare Extract, Anthemis Nobilis Flower Extract, Isohexadecane, Polysilicone-11, Methyldihydrojasmonate, Sodium Lactate, Disteardimonium Hectorite, Isododecane, Polyacrylate Crosspolymer-6, Squalane, Polyethylene, Propylene Carbonate, Pentylene Glycol, Disodium EDTA, BHT, Potassium Sorbate, Sodium Benzoate, Phenoxyethanol, Linalool, CI 14700, CI 19140
Cyclohexasiloxane
Alcohol Denat.
Niacinamide
Glycine Soja Oil
PPG-6-Decyltetradeceth-30
Retinol
Adenosine
Ammonium Polyacryloyldimethyl Taurate
Caprylyl Glycol
Citric Acid
Trisodium Ethylenediamine Disuccinate
Xanthan Gum
Retinyl Palmitate
Tocopherol
Parfum
Water, Glycerin, Cyclohexasiloxane, Alcohol Denat., Pentylene Glycol, Niacinamide, Dimethicone, Glycine Soja Oil, PPG-6-Decyltetradeceth-30, Sodium Hyaluronate, Retinol, Adenosine, Ammonium Polyacryloyldimethyl Taurate, Caprylyl Glycol, Citric Acid, Trisodium Ethylenediamine Disuccinate, Xanthan Gum, Polysilicone-11, Retinyl Palmitate, Tocopherol, Phenoxyethanol, Parfum
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:
Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.
On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.
Typical use levels in a formula run about 1-5%.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Polysilicone-11 is a film-forming silicone that creates a non-tacky and matte finish on the skin. It's commonly used to improve texture, absorb excess oil, and help active ingredients spread evenly.
Due to its "rubber-like" structure, it stays on the skin's surface instead of being absorbed. On the skin, it creates a flexible layer that enhances wearability and stability.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!