Educational guide
Estée Lauder Advanced Night Repair Intense Reset Concentrate Versus L'Oreal Age Perfect Cell Renewal Antioxidant Midnight Serum
Estée Lauder Advanced Night Repair Intense Reset Concentrate Versus L'Oreal Age Perfect Cell Renewal Antioxidant Midnight Serum This calming serum is formulated around Lactobacillus Ferment and Resveratrol to calm redness and strengthen the skin barrier. This
This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.
Estée Lauder Advanced Night Repair Intense Reset Concentrate Versus L'Oreal Age Perfect Cell Renewal Antioxidant Midnight Serum
This calming serum is formulated around Lactobacillus Ferment and Resveratrol to calm redness and strengthen the skin barrier.
This serum is formulated around Saccharomyces/Xylinum/Black Tea Ferment and Capryloyl Salicylic Acid to calm irritation and control oil.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Dimethicone
Glycerin
Methyl Trimethicone
Bis-PEG-18 Methyl Ether Dimethyl Silane
Butylene Glycol
Isopropyl Isostearate
PPG-15 Stearyl Ether
PEG-10 Dimethicone
Faex Extract
Tripeptide-32
Sodium Hyaluronate Crosspolymer
Sodium Hyaluronate
Hydrolyzed Sodium Hyaluronate
Hydrolyzed Algin
Lactobacillus Ferment
Adansonia Digitata Seed Extract
Soy Amino Acids
Aminopropyl Ascorbyl Phosphate
Resveratrol
Algae Extract
Salicylic Acid
Ergothioneine
Tocopheryl Acetate
Whey Protein
Avena Sativa Kernel Extract
Citrullus Lanatus Fruit Extract
Laminaria Digitata Extract
Lens Esculenta Fruit Extract
Pyrus Malus Fruit Extract
Caffeine
Sodium PCA
Propylene Glycol Caprylate
Triticum Vulgare Germ Extract
Lavandula Angustifolia Oil
Hordeum Vulgare Extract
Anthemis Nobilis Flower Extract
Isohexadecane
Polysilicone-11
Methyldihydrojasmonate
Sodium Lactate
Disteardimonium Hectorite
Isododecane
Polyacrylate Crosspolymer-6
Squalane
Polyethylene
Propylene Carbonate
Pentylene Glycol
Disodium EDTA
BHT
Potassium Sorbate
Sodium Benzoate
Phenoxyethanol
Linalool
CI 14700
CI 19140
Water, Dimethicone, Glycerin, Methyl Trimethicone, Bis-PEG-18 Methyl Ether Dimethyl Silane, Butylene Glycol, Isopropyl Isostearate, PPG-15 Stearyl Ether, PEG-10 Dimethicone, Faex Extract, Tripeptide-32, Sodium Hyaluronate Crosspolymer, Sodium Hyaluronate, Hydrolyzed Sodium Hyaluronate, Hydrolyzed Algin, Lactobacillus Ferment, Adansonia Digitata Seed Extract, Soy Amino Acids, Aminopropyl Ascorbyl Phosphate, Resveratrol, Algae Extract, Salicylic Acid, Ergothioneine, Tocopheryl Acetate, Whey Protein, Avena Sativa Kernel Extract, Citrullus Lanatus Fruit Extract, Laminaria Digitata Extract, Lens Esculenta Fruit Extract, Pyrus Malus Fruit Extract, Caffeine, Sodium PCA, Propylene Glycol Caprylate, Triticum Vulgare Germ Extract, Lavandula Angustifolia Oil, Hordeum Vulgare Extract, Anthemis Nobilis Flower Extract, Isohexadecane, Polysilicone-11, Methyldihydrojasmonate, Sodium Lactate, Disteardimonium Hectorite, Isododecane, Polyacrylate Crosspolymer-6, Squalane, Polyethylene, Propylene Carbonate, Pentylene Glycol, Disodium EDTA, BHT, Potassium Sorbate, Sodium Benzoate, Phenoxyethanol, Linalool, CI 14700, CI 19140
Alcohol Denat.
PEG-8
Dipropylene Glycol
Saccharomyces/Xylinum/Black Tea Ferment
Propylene Glycol
Tuber Aestivum Extract
Tuber Melanosporum Extract
Adenosine
Capryloyl Salicylic Acid
Neohesperidin Dihydrochalcone
Trisodium Ethylenediamine Disuccinate
Tocopherol
Octyldodecanol
Ammonium Polyacryloyldimethyl Taurate
Biosaccharide Gum-4
Biotin
Caprylyl Glycol
Citric Acid
Hydroxyethylcellulose
PEG-20 Methyl Glucose Sesquistearate
Sodium Citrate
Xanthan Gum
Bis-PEG/PPG-16/16 PEG/PPG-16/16 Dimethicone
Caprylic/Capric Triglyceride
Benzyl Alcohol
Hexyl Cinnamal
Hydroxycitronellal
Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate
Sodium Salicylate
Parfum
Water, Dimethicone, Glycerin, Alcohol Denat., PEG-8, Dipropylene Glycol, Saccharomyces/Xylinum/Black Tea Ferment, Propylene Glycol, Polysilicone-11, Bis-PEG-18 Methyl Ether Dimethyl Silane, Tuber Aestivum Extract, Tuber Melanosporum Extract, Adenosine, Capryloyl Salicylic Acid, Neohesperidin Dihydrochalcone, Sodium Hyaluronate, Trisodium Ethylenediamine Disuccinate, Tocopherol, Octyldodecanol, Squalane, Ammonium Polyacryloyldimethyl Taurate, Biosaccharide Gum-4, Biotin, Caprylyl Glycol, Citric Acid, Hydroxyethylcellulose, PEG-20 Methyl Glucose Sesquistearate, Sodium Citrate, Xanthan Gum, Bis-PEG/PPG-16/16 PEG/PPG-16/16 Dimethicone, Caprylic/Capric Triglyceride, Benzyl Alcohol, Hexyl Cinnamal, Hydroxycitronellal, CI 14700, CI 19140, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Phenoxyethanol, Potassium Sorbate, Sodium Benzoate, Sodium Salicylate, Parfum
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Bis-Peg-18 Methyl Ether Dimethyl Silane belongs to the siloxanes and silicones classes. It is synthetically created and has a waxy composition.
This ingredient is a humectant and emollient, meaning it helps hydrate the skin. Humectants draw moisture to your skin, while emollients prevent moisture from escaping.
Ci 14700, also known as Red No. 4, is a synthetic red dye derived from petroleum. It is water soluble.
CI 19140 is also known as Tartrazine. Tartrazine is a synthetic dye used in cosmetics, foods, and medicine to add a yellow color.
Tartrazine is created from petroleum and is water-soluble.
Some people may experience allergies from this dye, especially asthmatics and those with an aspirin intolerance.
Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Polysilicone-11 is a film-forming silicone that creates a non-tacky and matte finish on the skin. It's commonly used to improve texture, absorb excess oil, and help active ingredients spread evenly.
Due to its "rubber-like" structure, it stays on the skin's surface instead of being absorbed. On the skin, it creates a flexible layer that enhances wearability and stability.
Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.
This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.
Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.
You'll often find this ingredient used with other preservatives.
Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.
Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.
Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.
It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.
Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.
We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Squalane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).
It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.
This is due to how structurally similar it is to what your skin already produces.
Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.
Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.
No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).
Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.
This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.
Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.
Read more about squalene with an "e".
Though squalane is often called an oil, it’s technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.
The term “oil-free” isn’t regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.
Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.
A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.
The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!