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Estée Lauder Advanced Night Repair Eye Lift + Sculpt Eye Cream Versus Clarins Total Eye Lift

Estée Lauder Advanced Night Repair Eye Lift + Sculpt Eye Cream Versus Clarins Total Eye Lift This anti-aging eye moisturizer is formulated around Bifida Ferment Filtrate and Acetyl Hexapeptide-8 to soften the look of wrinkles and strengthen the skin barrier. T

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

Estée Lauder Advanced Night Repair Eye Lift + Sculpt Eye Cream Versus Clarins Total Eye Lift

This anti-aging eye moisturizer is formulated around Bifida Ferment Filtrate and Acetyl Hexapeptide-8 to soften the look of wrinkles and strengthen the skin barrier.

This anti-aging eye moisturizer is formulated around Caffeine to soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Dimethicone

Glycerin

Butylene Glycol

Isohexadecane

Bis-PEG-18 Methyl Ether Dimethyl Silane

PEG-10 Dimethicone

Disteardimonium Hectorite

Bifida Ferment Filtrate

Isopropyl Isostearate

PPG-15 Stearyl Ether

Tripeptide-32

Acetyl Hexapeptide-8

Hexapeptide-9

Bifida Ferment Lysate

Adansonia Digitata Seed Extract

Sodium Hyaluronate

Lactobacillus Ferment

Faex Extract

Aminopropyl Ascorbyl Phosphate

Laminaria Digitata Extract

Tocopherol

Tocopheryl Acetate

Caffeine

Algae Extract

Hydrolyzed Algin

Whey Protein

Helianthus Annuus Seed Extract

Citrullus Lanatus Fruit Extract

Lens Esculenta Fruit Extract

Pyrus Malus Fruit Extract

Hordeum Vulgare Extract

Glycine Soja Seed Extract

Cucumis Sativus Fruit Extract

Anthemis Nobilis Flower Extract

Betula Alba Bark Extract

Propylene Glycol Dicaprate

Sodium Polyaspartate

Sodium Lactate

Sodium Rna

Sodium PCA

Ethylhexylglycerin

Glucose

Sucrose

Fructose

Polyacrylate Crosspolymer-6

1,2-Hexanediol

Propylene Carbonate

Polysilicone-11

Hydroxyacetophenone

Lecithin

BHT

Disodium EDTA

Phenoxyethanol

Sodium Dehydroacetate

Potassium Sorbate

Sodium Benzoate

CI 77491

Water, Dimethicone, Glycerin, Butylene Glycol, Isohexadecane, Bis-PEG-18 Methyl Ether Dimethyl Silane, PEG-10 Dimethicone, Disteardimonium Hectorite, Bifida Ferment Filtrate, Isopropyl Isostearate, PPG-15 Stearyl Ether, Tripeptide-32, Acetyl Hexapeptide-8, Hexapeptide-9, Bifida Ferment Lysate, Adansonia Digitata Seed Extract, Sodium Hyaluronate, Lactobacillus Ferment, Faex Extract, Aminopropyl Ascorbyl Phosphate, Laminaria Digitata Extract, Tocopherol, Tocopheryl Acetate, Caffeine, Algae Extract, Hydrolyzed Algin, Whey Protein, Helianthus Annuus Seed Extract, Citrullus Lanatus Fruit Extract, Lens Esculenta Fruit Extract, Pyrus Malus Fruit Extract, Hordeum Vulgare Extract, Glycine Soja Seed Extract, Cucumis Sativus Fruit Extract, Anthemis Nobilis Flower Extract, Betula Alba Bark Extract, Propylene Glycol Dicaprate, Sodium Polyaspartate, Sodium Lactate, Sodium Rna, Sodium PCA, Ethylhexylglycerin, Glucose, Sucrose, Fructose, Polyacrylate Crosspolymer-6, 1,2-Hexanediol, Propylene Carbonate, Polysilicone-11, Hydroxyacetophenone, Lecithin, BHT, Disodium EDTA, Phenoxyethanol, Sodium Dehydroacetate, Potassium Sorbate, Sodium Benzoate, CI 77491

Caprylic/Capric Triglyceride

Propanediol

Cetearyl Alcohol

Betaine

Hydrogenated Coco-Glycerides

Panthenol

Glyceryl Stearate

PEG-100 Stearate

Pentylene Glycol

Butyrospermum Parkii Butter

Cetearyl Glucoside

Albizia Julibrissin Bark Extract

Acacia Farnesiana Flower Wax

Steareth-21

Carbomer

Chlorphenesin

CI 77891

Synthetic Fluorphlogopite

Escin

Parfum

Dimethiconol

Sodium Hydroxide

Alcohol

Harungana Madagascariensis Extract

Olea Europaea Fruit Extract

Paullinia Cupana Seed Extract

Tin Oxide

Acetyl Tetrapeptide-2

Dextran

Water, Glycerin, Caprylic/Capric Triglyceride, Propanediol, Cetearyl Alcohol, Betaine, Hydrogenated Coco-Glycerides, Panthenol, Glyceryl Stearate, PEG-100 Stearate, Pentylene Glycol, Butyrospermum Parkii Butter, Cetearyl Glucoside, Albizia Julibrissin Bark Extract, Acacia Farnesiana Flower Wax, Caffeine, Steareth-21, Dimethicone, Carbomer, Chlorphenesin, Ethylhexylglycerin, Tocopheryl Acetate, CI 77891, Synthetic Fluorphlogopite, Disodium EDTA, Escin, Parfum, Butylene Glycol, Dimethiconol, Sodium Hydroxide, Alcohol, Harungana Madagascariensis Extract, Olea Europaea Fruit Extract, Paullinia Cupana Seed Extract, Sodium Benzoate, Tin Oxide, Acetyl Tetrapeptide-2, Dextran

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Caffeine is a naturally occurring plant compound found in coffee beans, tea leaves, cocoa pods, and guarana.

As an antioxidant, caffeine protects your skin from free radical damage caused by UV exposure and envionrmnetal stressors.

Early research also shows that caffeine can help calm redness, soothe irritated skin, and support hair growth by stimulating microcirculation in the scalp.

You might have seen eye creams marketing caffeine as a depuffing ingredient. This is because it is a vasoconstrictor meaning it can temporarily constrict blood vessels, though clinical evidence for this specific use is still limited.

Most skincare products contain this ingredient at concentrations between 1-6%. It is able to penetrate skin easily regardless of skin type or thickness.

Just so you know, a very small number of case reports describe caffeine-induced allergy. This ingredient is generally well-tolerated, non-irritating, and non-sensitizing for the majority of people.

Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.

What it does:

Dimethicone comes in different viscosities:

Depending on the viscosity, dimethicone has different properties.

Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.

This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.

Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.

Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.

This ingredient mainly works behind the scenes and helps with:

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.

Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.

Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.

It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.

Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.

We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.

Tocopheryl Acetate is a stable, shelf-friendly form of vitamin E.

Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.

It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.

One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.

Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.

Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.

The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.

Most leave-on skincare keeps it at the lower end, often between 0.5-1%.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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