EPO (Erythropoietin) Dosage Chart - Peptide Dosages

For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

EPO (Erythropoietin, 3000 IU) Dosage Protocol

Recombinant human erythropoietin (rHuEPO), a glycoprotein hormone that drives red-blood-cell production. It is dosed in international units (IU), and is one of the best-known and most dangerous blood-doping agents — presented here as a research reference and a safety warning.

Why EPO draws research interest

These are the directions researchers and the peptide community most often explore EPO for — so you know you’re in the right place. They describe what is being studied, not proven benefits, approved uses, or promised results.

It is a real drug — and that is exactly why misuse is dangerous

Recombinant EPO is a genuine, life-improving medicine for anemia of kidney disease, given under close medical supervision with blood monitoring. The danger comes from using it without that supervision: the same red-cell-raising action that helps an anemic patient becomes a thrombosis risk when someone with a normal blood count pushes their hematocrit higher for performance.

Thicker blood is the whole risk

EPO does not act on muscle or metabolism directly; it raises the number of red cells. That increases oxygen delivery, but it also increases blood viscosity. Landmark clinical trials found that targeting higher hemoglobin with these agents significantly raised stroke, hypertension and vascular-access thrombosis, and even in healthy volunteers EPO measurably activated the clotting system. This is the mechanism behind the deaths historically linked to EPO abuse in cycling.

It is IU-dosed, and it is caught

Unlike most compounds on this site, EPO is measured in international units, not milligrams — a reflection of its being a hormone defined by biological activity. It is also one of the most heavily policed doping agents: laboratories distinguish recombinant from natural EPO by glycan isoforms, and the Athlete Biological Passport flags non-physiological changes in red-cell parameters over time.

Evidence ranges from early laboratory work to clinical trials depending on the use — the sections below cover the actual data and sources.

Mix & measure EPO · 3000 mg

Pre-filled with this protocol’s recommended BAC water and documented starting dose — edit any field to run your own numbers.

Reconstitution math only — not dosing advice. U-100 syringe: 100 units = 1 mL. Full reconstitution guide → · Advanced calculator →

A glycoprotein hormone made by the kidney that binds the erythropoietin receptor on marrow red-cell progenitors and drives their survival and proliferation, raising red-blood-cell mass and oxygen-carrying capacity. The recombinant drug reproduces this to correct anemia.

Dosed in international units (IU), always individualized by a clinician in real medicine and titrated to the lowest hemoglobin that avoids transfusion. This reference provides no administration dose. A 3000 IU vial in 1 mL bacteriostatic water is 3000 IU/mL.

The clinical evidence is strong that pushing hemoglobin too high with erythropoiesis-stimulating agents increases stroke, hypertension and vascular thrombosis. In sport it boosts endurance but is banned and dangerous; healthy-subject studies show it activates the clotting system.

Quickstart Highlights

Erythropoietin (EPO) is a glycoprotein hormone — naturally produced by the kidney — that signals the bone marrow to make more red blood cells. The recombinant form (rHuEPO, or epoetin) is a genuine, FDA-approved medicine used to treat anemia in chronic kidney disease and certain other conditions. It is a hormone, not a small peptide, and it is dosed in international units (IU) rather than milligrams[1].

This page is an educational reference on what EPO is, how it works, and why it is dangerous outside clinical supervision. It is not medical advice and not an administration protocol. Research-grade EPO is not the approved medicinal product, and EPO’s most notorious non-medical use — blood doping in endurance sport — is prohibited and carries a serious risk of clots, stroke and death[4][5]. The information below explains the science and the hazard; it does not tell anyone how to use the hormone.

A kidney-derived glycoprotein hormone that stimulates red-blood-cell production; the recombinant version (rHuEPO/epoetin) is FDA-approved for anemia but sold here as a research reagent[1].

EPO is measured in international units (IU), not mg. A 3000 IU vial reconstituted with 1 mL bacteriostatic water is 3000 IU/mL. This is a lab-handling reference only.

Raising red-cell mass thickens the blood. In controlled trials, driving hemoglobin higher with EPO increased stroke, hypertension and thrombosis[2][3]; in healthy people it activates clotting[5]. Abuse has been linked to serious cardiovascular events.

A prohibited doping agent in sport, detectable by isoform testing and the Athlete Biological Passport[4]. Research-grade material is not the approved medicine, and there is no safe self-administration context.

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Related questions

01Davunetide — frequently asked questions

Wipe the stopper with an alcohol swab, then inject your bacteriostatic water slowly down the inside wall of the vial. Let it sit and gently swirl until dissolved — never shake. Store the mixed vial in the refrigerator and draw doses with an insulin syringe. Use the calculator above to turn any dose into syringe units. There is no single correct amount — more water simply spreads the same 5 mg of peptide across a larger volume, which makes small doses easier to measure accurately. 1 to 3 mL per vial is typical. Enter your chosen volume in the calculator above to see the resulting concentration and syringe units. On a U-100 insulin syringe, 100 units equal 1 mL, so 1 unit equals 0.01 mL. The calculator above converts your draw volume into these units automatically so you can measure without doing the math by hand. Keep the reconstituted vial refrigerated at roughly 2 to 8 degrees Celsius, away from light, and avoid freezing it. Reconstituted research peptides are generally used within a few weeks. Always follow the specific guidance supplied with your product. Divide the vial strength of 5 mg by the amount you use per injection. The calculator above reports this as "doses per vial" the moment you enter a dose. No. Davunetide is sold strictly for laboratory and research purposes and is not approved by the FDA or other regulators for human use. Everything on this page is research information, not medical advice — consult a licensed healthcare professional before any use.

Source: dosagepeptide.com ↗

02Ecnoglutide — frequently asked questions

Wipe the stopper with an alcohol swab, then inject your bacteriostatic water slowly down the inside wall of the vial. Let it sit and gently swirl until dissolved — never shake. Store the mixed vial in the refrigerator and draw doses with an insulin syringe. Use the calculator above to turn any dose into syringe units. There is no single correct amount — more water simply spreads the same 10 mg of peptide across a larger volume, which makes small doses easier to measure accurately. 1 to 3 mL per vial is typical. Enter your chosen volume in the calculator above to see the resulting concentration and syringe units. On a U-100 insulin syringe, 100 units equal 1 mL, so 1 unit equals 0.01 mL. The calculator above converts your draw volume into these units automatically so you can measure without doing the math by hand. Keep the reconstituted vial refrigerated at roughly 2 to 8 degrees Celsius, away from light, and avoid freezing it. Reconstituted research peptides are generally used within a few weeks. Always follow the specific guidance supplied with your product. Divide the vial strength of 10 mg by the amount you use per injection. The calculator above reports this as "doses per vial" the moment you enter a dose. No. Ecnoglutide is sold strictly for laboratory and research purposes and is not approved by the FDA or other regulators for human use. Everything on this page is research information, not medical advice — consult a licensed healthcare professional before any use.

Source: dosagepeptide.com ↗

03Teduglutide — frequently asked questions

Wipe the stopper with an alcohol swab, then inject your bacteriostatic water slowly down the inside wall of the vial. Let it sit and gently swirl until dissolved — never shake. Store the mixed vial in the refrigerator and draw doses with an insulin syringe. Use the calculator above to turn any dose into syringe units. There is no single correct amount — more water simply spreads the same 5 mg of peptide across a larger volume, which makes small doses easier to measure accurately. 1 to 3 mL per vial is typical. Enter your chosen volume in the calculator above to see the resulting concentration and syringe units. On a U-100 insulin syringe, 100 units equal 1 mL, so 1 unit equals 0.01 mL. The calculator above converts your draw volume into these units automatically so you can measure without doing the math by hand. Keep the reconstituted vial refrigerated at roughly 2 to 8 degrees Celsius, away from light, and avoid freezing it. Reconstituted research peptides are generally used within a few weeks. Always follow the specific guidance supplied with your product. Divide the vial strength of 5 mg by the amount you use per injection. The calculator above reports this as "doses per vial" the moment you enter a dose. No. Teduglutide is sold strictly for laboratory and research purposes and is not approved by the FDA or other regulators for human use. Everything on this page is research information, not medical advice — consult a licensed healthcare professional before any use.

Source: dosagepeptide.com ↗

04Pemvidutide — frequently asked questions

Wipe the stopper with an alcohol swab, then inject your bacteriostatic water slowly down the inside wall of the vial. Let it sit and gently swirl until dissolved — never shake. Store the mixed vial in the refrigerator and draw doses with an insulin syringe. Use the calculator above to turn any dose into syringe units. There is no single correct amount — more water simply spreads the same 5 mg of peptide across a larger volume, which makes small doses easier to measure accurately. 1 to 3 mL per vial is typical. Enter your chosen volume in the calculator above to see the resulting concentration and syringe units. On a U-100 insulin syringe, 100 units equal 1 mL, so 1 unit equals 0.01 mL. The calculator above converts your draw volume into these units automatically so you can measure without doing the math by hand. Keep the reconstituted vial refrigerated at roughly 2 to 8 degrees Celsius, away from light, and avoid freezing it. Reconstituted research peptides are generally used within a few weeks. Always follow the specific guidance supplied with your product. Divide the vial strength of 5 mg by the amount you use per injection. The calculator above reports this as "doses per vial" the moment you enter a dose. No. Pemvidutide is sold strictly for laboratory and research purposes and is not approved by the FDA or other regulators for human use. Everything on this page is research information, not medical advice — consult a licensed healthcare professional before any use.

Source: dosagepeptide.com ↗

05VK2735 — frequently asked questions

Wipe the stopper with an alcohol swab, then inject your bacteriostatic water slowly down the inside wall of the vial. Let it sit and gently swirl until dissolved — never shake. Store the mixed vial in the refrigerator and draw doses with an insulin syringe. Use the calculator above to turn any dose into syringe units. There is no single correct amount — more water simply spreads the same 10 mg of peptide across a larger volume, which makes small doses easier to measure accurately. 1 to 3 mL per vial is typical. Enter your chosen volume in the calculator above to see the resulting concentration and syringe units. On a U-100 insulin syringe, 100 units equal 1 mL, so 1 unit equals 0.01 mL. The calculator above converts your draw volume into these units automatically so you can measure without doing the math by hand. Keep the reconstituted vial refrigerated at roughly 2 to 8 degrees Celsius, away from light, and avoid freezing it. Reconstituted research peptides are generally used within a few weeks. Always follow the specific guidance supplied with your product. Divide the vial strength of 10 mg by the amount you use per injection. The calculator above reports this as "doses per vial" the moment you enter a dose. No. VK2735 is sold strictly for laboratory and research purposes and is not approved by the FDA or other regulators for human use. Everything on this page is research information, not medical advice — consult a licensed healthcare professional before any use.

Source: dosagepeptide.com ↗

Research context

Read sources and limitations before applying a claim.

Research Models and Methodology: How This Question Is Studied

Because the clinical evidence is thin, most of what is known about NAD+ and Parkinson’s biology comes from experimental models, and understanding those models is essential to interpreting the claims made from them. The methodology spans several scales, each with characteristic strengths and blind spots. At the cellular level, researchers use dopaminergic cell lines and induced pluripotent stem cell (iPSC)-derived neurons, sometimes carrying Parkinson’s-associated mutations such as PINK1, PRKN, LRRK2, or GBA. These systems allow precise measurement of NAD+/NADH ratios, mitochondrial membrane potential, oxygen-consumption rate (via Seahorse-type respirometry), ATP output, mitophagy flux, and alpha-synuclein aggregation, and they permit clean genetic and pharmacological manipulation. Their limitation is context: a neuron in a dish lacks the aging, the vasculature, the glial partners, and the decades-long timescale of human disease. A compound that restores NAD+ and rescues mitochondrial function in a two-week culture experiment has cleared a low bar relative to a human brain.5,6 At the organismal level, the workhorses are toxin and genetic models. Toxin models use complex I inhibitors, chiefly MPTP in mice and non-human primates and rotenone in rats, to acutely damage dopaminergic neurons; these reproduce the bioenergetic lesion and motor deficits but not the slow, spreading, age-dependent synucleinopathy of human disease. Genetic models overexpress human alpha-synuclein or knock out mitophagy genes, capturing aspects of aggregation and quality-control failure but often with incomplete nigral cell loss. Invertebrate models in Drosophila and C. elegans allow rapid, high-throughput testing of NAD+ manipulation on survival and locomotion. Across these systems, NAD+ boosting has repeatedly improved outcomes, which is encouraging but must be weighted by the well-documented poor translation of Parkinson’s models to human neuroprotection.1 The methodological centerpiece of the human work is target engagement measurement. It is not enough to give an oral precursor and hope; investigators need to know whether brain NAD+ actually changed. The NADPARK program used phosphorus-31 magnetic resonance spectroscopy, a non-invasive technique that detects NAD+ and NADH resonances in living brain tissue, to demonstrate that oral NR raised cerebral NAD+ in a subset of participants.1 This is a genuine methodological advance, because it converts a plausibility argument (“the precursor should reach the brain”) into a measurement, and it also revealed the important reality of responders and non-responders: not everyone who took NR showed a rise in brain NAD+, which has major implications for trial design and for interpreting any downstream clinical effect. Complementary readouts included FDG-PET for cerebral glucose metabolism, cerebrospinal fluid metabolomics, and blood and skeletal-muscle transcriptomics to trace the systemic response.1 Clinical outcome measurement introduces its own methodology. The standard instrument is the Movement Disorder Society Unified Parkinson’s Disease Rating Scale (MDS-UPDRS), a multi-part rating of motor and non-motor function. It is the accepted primary-endpoint measure in NOPARK, but it has meaningful test-retest variability, is sensitive to the timing of symptomatic dopaminergic medication, and depends partly on examiner judgment. This is precisely why the NR-SAFE authors flagged levodopa-timing as a possible confounder of their UPDRS signal, and why short trials are ill-suited to detecting the slow separation of progression curves that disease modification would produce.2 A well-designed efficacy trial therefore needs adequate size, a long enough duration for progression to manifest, blinding, standardized assessment conditions, and ideally pre-specified biomarker sub-analyses to separate responders from non-responders. The gap between the elegant mechanistic experiments and the demanding requirements of a convincing clinical trial is exactly where enthusiasm most often outruns evidence.

Source: dosagepeptide.com ↗

2. Research use only

Any protocols, measurements, or instructions described are based on publicly available research data or general knowledge in the field. They are intended solely for research and educational reference, not for human or veterinary therapeutic use.

Source: dosagepeptide.com ↗

Practical and safety references

These excerpts are educational, not personalised medical instructions.

How-to reference

How to convert mcg to mg (and back)

Because the factor is exactly 1000, every conversion is a decimal-point move of three places — no calculator strictly required once you see the pattern: mcg → mg: divide by 1000, i.e. move the decimal point three places to the left. 500 mcg → 0.5 mg; 100 mcg → 0.1 mg; 1500 mcg → 1.5 mg. mg → mcg: multiply by 1000, i.e. move the decimal point three places to the right. 0.5 mg → 500 mcg; 2 mg → 2000 mcg; 1.25 mg → 1250 mcg. The tool above does the same move for you and trims trailing zeros, so you can paste in any value — whole or fractional — and read the exact counterpart.

Source: dosagepeptide.com ↗

Dosage reference

Cardiogen (20mg Vial) Dosage Protocol

Khavinson cardiovascular short-peptide bioregulator (AEDR) — research-only; not FDA/EMA approved, benefits unproven.

Source: dosagepeptide.com ↗

About the author

Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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EPO (Erythropoietin, 3000 IU) Dosage Protocol

Why EPO draws research interest

It is a real drug — and that is exactly why misuse is dangerous

Thicker blood is the whole risk

It is IU-dosed, and it is caught

Mix & measure EPO · 3000 mg

Quickstart Highlights

Related questions

Research Models and Methodology: How This Question Is Studied

2. Research use only

How to convert mcg to mg (and back)

Cardiogen (20mg Vial) Dosage Protocol

Peptide Therapy Guide Editorial Team

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