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Elizabeth Arden Prevage Anti-Aging Overnight Cream Versus Estée Lauder Advanced Night Repair Synchronized Multi-Recovery Complex Serum

Elizabeth Arden Prevage Anti-Aging Overnight Cream Versus Estée Lauder Advanced Night Repair Synchronized Multi-Recovery Complex Serum This anti-aging night moisturizer is formulated around Butyrospermum Parkii Butter and Hydroxypinacolone Retinoate to soften

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

Elizabeth Arden Prevage Anti-Aging Overnight Cream Versus Estée Lauder Advanced Night Repair Synchronized Multi-Recovery Complex Serum

This anti-aging night moisturizer is formulated around Butyrospermum Parkii Butter and Hydroxypinacolone Retinoate to soften the look of wrinkles and hydrate skin.

This barrier-repair serum is formulated around Bifida Ferment Lysate and Sodium Hyaluronate to strengthen the skin barrier and soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Butyrospermum Parkii Butter

Cyclopentasiloxane

Glycerin

Dimethicone

PEG-8 Dimethicone

Butylene Glycol

Cetearyl Alcohol

Theobroma Cacao Seed Butter

Phytosteryl Macadamiate

PPG-2 Isoceteth-20 Acetate

Dipentaerythrityl Hexacaprylate/Hexacaprate

Tridecyl Trimellitate

C12-15 Alkyl Benzoate

Caprylyl Glycol

Caprylyl Methicone

Carbomer

Cetearyl Glucoside

Cyclohexasiloxane

Dimethicone Crosspolymer

Dimethiconol

Dimethyl Isosorbide

Disodium EDTA

Glyceryl Stearate

Hexylene Glycol

Hydrogenated Lecithin

Hydrogenated Phosphatidylcholine

Hydrogenated Polydecene

Hydroxydecyl Ubiquinoyl Dipalmitoyl Glycerate

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Hydroxypinacolone Retinoate

Isohexadecane

Lactobacillus/Lemon Peel Ferment Extract

Leuconostoc/Radish Root Ferment Filtrate

Mica

Neopentyl Glycol Dicaprylate/Dicaprate

Parfum

PEG-100 Stearate

PEG-8

Phenyl Trimethicone

Phospholipids

Polyphosphorylcholine Glycol Acrylate

Polyquaternium-51

Polysorbate 60

Propylene Glycol

Sodium Hyaluronate

Sodium Hydroxide

Sodium PCA

Solanum Lycopersicum Fruit Extract

Stearoxymethicone/Dimethicone Copolymer

Sucrose

Tocopheryl Acetate

Trehalose

Tridecyl Stearate

Urea

Xanthan Gum

Alpha-Isomethyl Ionone

Linalool

Benzoic Acid

Chlorphenesin

Methylparaben

Phenoxyethanol

CI 77492

CI 14700

CI 77891

CI 19140

Water, Butyrospermum Parkii Butter, Cyclopentasiloxane, Glycerin, Dimethicone, PEG-8 Dimethicone, Butylene Glycol, Cetearyl Alcohol, Theobroma Cacao Seed Butter, Phytosteryl Macadamiate, PPG-2 Isoceteth-20 Acetate, Dipentaerythrityl Hexacaprylate/Hexacaprate, Tridecyl Trimellitate, C12-15 Alkyl Benzoate, Caprylyl Glycol, Caprylyl Methicone, Carbomer, Cetearyl Glucoside, Cyclohexasiloxane, Dimethicone Crosspolymer, Dimethiconol, Dimethyl Isosorbide, Disodium EDTA, Glyceryl Stearate, Hexylene Glycol, Hydrogenated Lecithin, Hydrogenated Phosphatidylcholine, Hydrogenated Polydecene, Hydroxydecyl Ubiquinoyl Dipalmitoyl Glycerate, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Hydroxypinacolone Retinoate, Isohexadecane, Lactobacillus/Lemon Peel Ferment Extract, Leuconostoc/Radish Root Ferment Filtrate, Mica, Neopentyl Glycol Dicaprylate/Dicaprate, Parfum, PEG-100 Stearate, PEG-8, Phenyl Trimethicone, Phospholipids, Polyphosphorylcholine Glycol Acrylate, Polyquaternium-51, Polysorbate 60, Propylene Glycol, Sodium Hyaluronate, Sodium Hydroxide, Sodium PCA, Solanum Lycopersicum Fruit Extract, Stearoxymethicone/Dimethicone Copolymer, Sucrose, Tocopheryl Acetate, Trehalose, Tridecyl Stearate, Urea, Xanthan Gum, Alpha-Isomethyl Ionone, Linalool, Benzoic Acid, Chlorphenesin, Methylparaben, Phenoxyethanol, CI 77492, CI 14700, CI 77891, CI 19140

Bifida Ferment Lysate

Propanediol

Bis-PEG-18 Methyl Ether Dimethyl Silane

Methyl Gluceth-20

Glycereth-26

PEG-75

Adansonia Digitata Seed Extract

Tripeptide-32

Faex Extract

Lactobacillus Ferment

Cola Acuminata Seed Extract

Anthemis Nobilis Flower Extract

Hydrolyzed Algin

Pantethine

Caffeine

Lecithin

Sodium Rna

Bisabolol

Squalane

Oleth-3 Phosphate

Oleth-3

Oleth-5

Choleth-24

Jojoba Wax PEG-120 Esters

Ceteth-24

Triethanolamine

Tetrasodium EDTA

BHT

Potassium Sorbate

Water, Bifida Ferment Lysate, PEG-8, Propanediol, Bis-PEG-18 Methyl Ether Dimethyl Silane, Methyl Gluceth-20, Glycereth-26, PEG-75, Butylene Glycol, Adansonia Digitata Seed Extract, Tripeptide-32, Sodium Hyaluronate, Faex Extract, Lactobacillus Ferment, Cola Acuminata Seed Extract, Anthemis Nobilis Flower Extract, Hydrolyzed Algin, Pantethine, Caffeine, Lecithin, Sodium Rna, Bisabolol, Squalane, Glycerin, Oleth-3 Phosphate, Caprylyl Glycol, Oleth-3, Oleth-5, Choleth-24, Hydrogenated Lecithin, Jojoba Wax PEG-120 Esters, Ceteth-24, Tocopheryl Acetate, Carbomer, Triethanolamine, Tetrasodium EDTA, BHT, Xanthan Gum, Potassium Sorbate, Disodium EDTA, Phenoxyethanol, CI 14700, CI 19140

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.

Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.

It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.

Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.

A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.

Ci 14700, also known as Red No. 4, is a synthetic red dye derived from petroleum. It is water soluble.

CI 19140 is also known as Tartrazine. Tartrazine is a synthetic dye used in cosmetics, foods, and medicine to add a yellow color.

Tartrazine is created from petroleum and is water-soluble.

Some people may experience allergies from this dye, especially asthmatics and those with an aspirin intolerance.

Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.

This ingredient mainly works behind the scenes and helps with:

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Hydrogenated Lecithin is a more stable version of lecithin.

It's made by taking lecithin (a phospholipid commonly found in soybeans and egg yolks) and hydrogenating it. This just means the unsaturated fatty acids are turned into saturated ones so they don't go bad as easily.

This ingredient is an emollient, emulsifier, and penetration enhancer. As an emollient, it helps soften and hydrate skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.

Hydrogenated Lecithin can form tiny spherical structures made of phospholipid bilayers called liposomes. These liposomes are able to capture compounds inside their structure and deliver them through the skin barrier.

Because phospholipids are a natural component of our cell membranes, this ingredient is inherently compatible with skin.

A 2021 study found lecithin-based surfactants were less harsh and more tolerable comared to Sodium Lauryl Sulfate (SLS).

PEG-8 is a synthetic polymer used as a humectant and solvent.

This ingredient is able to help dissolve active ingredients, including water. This gives it humectant properties.

It is soluble in water. The number '8' stands for the molecular weight of the ingredient.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Tocopheryl Acetate is a stable, shelf-friendly form of vitamin E.

Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.

It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.

One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.

Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.

Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.

The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.

Most leave-on skincare keeps it at the lower end, often between 0.5-1%.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

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Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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