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DRMTLGY HPR Eye Cream Versus Biossance Squalane + Marine Algae Eye Cream

DRMTLGY HPR Eye Cream Versus Biossance Squalane + Marine Algae Eye Cream This anti-aging eye moisturizer is formulated around Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7 to soften the look of wrinkles and refine skin texture. This anti-aging eye moistu

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

DRMTLGY HPR Eye Cream Versus Biossance Squalane + Marine Algae Eye Cream

This anti-aging eye moisturizer is formulated around Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7 to soften the look of wrinkles and refine skin texture.

This anti-aging eye moisturizer is formulated around Squalane and Palmitoyl Tripeptide-5 to soften the look of wrinkles and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Cucurbita Pepo Seed Oil

Dimethicone

Isopropyl Palmitate

Dimethyl Isosorbide

Glycol Distearate

Stearic Acid

Stearyl Alcohol

Palmitoyl Tripeptide-1

Palmitoyl Tetrapeptide-7

Hydroxypinacolone Retinoate

Oleic Acid

Terminalia Arjuna Extract

Cocos Nucifera Oil

Rosa Canina Fruit Oil

Glyceryl Stearate

PEG-100 Stearate

Allantoin

Tocopheryl Acetate

Chrysin

Butylene Glycol

Carbomer

Titanium Dioxide

N-Hydroxysuccinimide

Steareth-20

Lecithin

Phenoxyethanol

Ethylhexylglycerin

Sodium Hydroxide

Disodium EDTA

Polysorbate 20

Water, Glycerin, Cucurbita Pepo Seed Oil, Dimethicone, Isopropyl Palmitate, Dimethyl Isosorbide, Glycol Distearate, Stearic Acid, Stearyl Alcohol, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Hydroxypinacolone Retinoate, Oleic Acid, Terminalia Arjuna Extract, Cocos Nucifera Oil, Rosa Canina Fruit Oil, Glyceryl Stearate, PEG-100 Stearate, Allantoin, Tocopheryl Acetate, Chrysin, Butylene Glycol, Carbomer, Titanium Dioxide, N-Hydroxysuccinimide, Steareth-20, Lecithin, Phenoxyethanol, Ethylhexylglycerin, Sodium Hydroxide, Disodium EDTA, Polysorbate 20

Caprylic/Capric Triglyceride

Squalane

Sorbitan Olivate

Cetearyl Olivate

Jojoba Esters

Glyceryl Stearate Se

Panthenol

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Cetyl Palmitate

Spilanthes Acmella Flower Extract

Palmitoyl Tripeptide-5

Sorbitan Palmitate

Dunaliella Salina Extract

Astaxanthin

Sodium Hyaluronate

Tocopherol

Citric Acid

Water, Caprylic/Capric Triglyceride, Squalane, Glycerin, Sorbitan Olivate, Cetearyl Olivate, Jojoba Esters, Glyceryl Stearate Se, Panthenol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Cetyl Palmitate, Spilanthes Acmella Flower Extract, Palmitoyl Tripeptide-5, Sorbitan Palmitate, Dunaliella Salina Extract, Astaxanthin, Sodium Hyaluronate, Phenoxyethanol, Ethylhexylglycerin, Tocopherol, Citric Acid

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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