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Dr. Loretta Micro Peel Peptide Pads Versus Sofie Pavitt Face Mandelic Clearing Serum

Dr. Loretta Micro Peel Peptide Pads Versus Sofie Pavitt Face Mandelic Clearing Serum This smoothing exfoliating pad uses a pre-saturated pad with Glycolic Acid and Lactobacillus Ferment to refine skin texture and brighten dull-looking skin. This acne serum is

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

Dr. Loretta Micro Peel Peptide Pads Versus Sofie Pavitt Face Mandelic Clearing Serum

This smoothing exfoliating pad uses a pre-saturated pad with Glycolic Acid and Lactobacillus Ferment to refine skin texture and brighten dull-looking skin.

This acne serum is formulated around Mandelic Acid to clear breakouts and refine skin texture.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycolic Acid

Glycerin

Sodium Hydroxide

Lactobacillus Ferment

Xanthan Gum

Butylene Glycol

Cola Nitida Seed Extract

Pinus Koraiensis Seed Extract

Paullinia Cupana Seed Extract

Ahnfeltia Concinna Extract

Phenoxyethanol

Chlorphenesin

Sodium Dehydroacetate

Sodium Benzoate

Sorbic Acid

Water, Glycolic Acid, Glycerin, Sodium Hydroxide, Lactobacillus Ferment, Xanthan Gum, Butylene Glycol, Cola Nitida Seed Extract, Pinus Koraiensis Seed Extract, Paullinia Cupana Seed Extract, Ahnfeltia Concinna Extract, Phenoxyethanol, Chlorphenesin, Sodium Dehydroacetate, Sodium Benzoate, Sorbic Acid

Mandelic Acid

Propanediol

Panthenol

Polyacrylate Crosspolymer-6

Glyceryl Acrylate/Acrylic Acid Copolymer

Hydrolyzed Sodium Hyaluronate

Hyaluronic Acid

Silanetriol

Citric Acid

Sodium Phytate

Hexylene Glycol

Caprylyl Glycol

Caramel

Water, Mandelic Acid, Propanediol, Sodium Hydroxide, Panthenol, Glycerin, Polyacrylate Crosspolymer-6, Xanthan Gum, Butylene Glycol, Glyceryl Acrylate/Acrylic Acid Copolymer, Hydrolyzed Sodium Hyaluronate, Hyaluronic Acid, Silanetriol, Citric Acid, Sorbic Acid, Sodium Phytate, Hexylene Glycol, Caprylyl Glycol, Phenoxyethanol, Caramel

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.

Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.

"Alkaline" refers to a high pH level. A low pH level would be considered acidic.

Sorbic Acid is a preservative that stops your product from spoiling by stopping microbes from growing.

As a preservative, it's kind of a specialist: it has a broad spectrum of activity against yeast and molds but is weaker against bacteria. That's why it's often paired with another preservative to cover that gap.

This ingredient is also pretty picky about pH; it performs best at pH 6.5 or below.

At the right pH level, sorbic acid is "active" and can slip through the outer wall of a microbe. Once inside, it turns the cell's interior more acidic to shut down the microbe from the inside.

The EU caps this ingredient at 0.6% while the CIR has concluded it's safe at concentrations up to 1%. It's most often used around 0.05-0.2% in cosmetics.

Though this ingredient is considered low-sensitizing and well-tolerated, a very small number of people may have a contact allergy to it. Be sure to patch test if you have a history of allergies towards preservatives.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

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About the author

Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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