Diego Dalla Palma Professional 24-Hour Hydro Replenishing Cream Versus Summer Fridays Cloud Dew Oil-Free Gel Cream Moisturizer

Diego Dalla Palma Professional 24-Hour Hydro Replenishing Cream Versus Summer Fridays Cloud Dew Oil-Free Gel Cream Moisturizer

This barrier-repair moisturizer is formulated around Acetyl Glucosamine and Sodium Hyaluronate to strengthen the skin barrier and hydrate skin.

This barrier-repair moisturizer is formulated around Sodium Hyaluronate and Hydrolyzed Sodium Hyaluronate to strengthen the skin barrier and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Diethylhexyl Carbonate

Caprylic/Capric Triglyceride

Propanediol

Cetyl Alcohol

Glyceryl Stearate

PEG-75 Stearate

Betaine

Acetyl Glucosamine

Butyrospermum Parkii Butter

Sodium Hyaluronate

Passiflora Edulis Seed Oil

Euterpe Oleracea Fruit Oil

Orbignya Oleifera Seed Oil

Trehalose

Erythritol

Tocopheryl Acetate

Hydrolyzed Glycosaminoglycans

Hydrolyzed Sodium Hyaluronate

Niacinamide

Oryza Sativa Bran Oil

Xanthan Gum

Parfum

Phenoxyethanol

Sodium Lactate

Sodium Starch Octenylsuccinate

Aluminum Starch Octenylsuccinate

Sodium Polyacrylate

Ceteth-20

Steareth-20

Lecithin

Alanine

Phenylalanine

Valine

Lysine

Isoleucine

Leucine

Tyrosine

Glycine

Arginine

Histidine

Aspartic Acid

Glutamic Acid

Calcium Pantothenate

Yeast Amino Acids

Biotin/Folic Acid/Cyanocobalamin/Niacinamide/Pantothenic Acid/Pyridoxine/Riboflavin/Thiamine/Yeast Polypeptides

Saccharomyces/Copper Ferment

Saccharin

Saccharomyces/Magnesium Ferment

Saccharomyces/Silicon Ferment

Saccharomyces/Zinc Ferment

Threonine

Proline

Serine

Pyridoxine Hcl

Methionine

Cysteine

Tryptophan

Maltodextrin

Urea

Tocopherol

Mannitol

Disodium Adenosine Triphosphate

Sodium Ascorbyl Phosphate

Rna

Retinyl Palmitate

Ascorbyl Palmitate

Tropolone

Ceramide NP

Sorbitol

Histidine Hcl

Ubiquinone

Taurine

Inositol

DNA

Cholesterol

Citric Acid

Ceramide AP

Phytosphingosine

Thioctic Acid

Carbomer

Glyceryl Linoleate

Glyceryl Linolenate

Ceramide EOP

Sodium Gluconate

Disodium EDTA

Glycerin

Glyceryl Caprylate

Sodium Polyglutamate

Silica

Caprylyl Glycol

Potassium Sorbate

Butylene Glycol

Dimethicone

Hydroxycitronellal

Hexyl Cinnamal

Linalool

Alpha-Isomethyl Ionone

Limonene

Citronellol

Coumarin

Geraniol

Water, Diethylhexyl Carbonate, Caprylic/Capric Triglyceride, Propanediol, Cetyl Alcohol, Glyceryl Stearate, PEG-75 Stearate, Betaine, Acetyl Glucosamine, Butyrospermum Parkii Butter, Sodium Hyaluronate, Passiflora Edulis Seed Oil, Euterpe Oleracea Fruit Oil, Orbignya Oleifera Seed Oil, Trehalose, Erythritol, Tocopheryl Acetate, Hydrolyzed Glycosaminoglycans, Hydrolyzed Sodium Hyaluronate, Niacinamide, Oryza Sativa Bran Oil, Xanthan Gum, Parfum, Phenoxyethanol, Sodium Lactate, Sodium Starch Octenylsuccinate, Aluminum Starch Octenylsuccinate, Sodium Polyacrylate, Ceteth-20, Steareth-20, Lecithin, Alanine, Phenylalanine, Valine, Lysine, Isoleucine, Leucine, Tyrosine, Glycine, Arginine, Histidine, Aspartic Acid, Glutamic Acid, Calcium Pantothenate, Yeast Amino Acids, Biotin/Folic Acid/Cyanocobalamin/Niacinamide/Pantothenic Acid/Pyridoxine/Riboflavin/Thiamine/Yeast Polypeptides, Saccharomyces/Copper Ferment, Saccharin, Saccharomyces/Magnesium Ferment, Saccharomyces/Silicon Ferment, Saccharomyces/Zinc Ferment, Threonine, Proline, Serine, Pyridoxine Hcl, Methionine, Cysteine, Tryptophan, Maltodextrin, Urea, Tocopherol, Mannitol, Disodium Adenosine Triphosphate, Sodium Ascorbyl Phosphate, Rna, Retinyl Palmitate, Ascorbyl Palmitate, Tropolone, Ceramide NP, Sorbitol, Histidine Hcl, Ubiquinone, Taurine, Inositol, DNA, Cholesterol, Citric Acid, Ceramide AP, Phytosphingosine, Thioctic Acid, Carbomer, Glyceryl Linoleate, Glyceryl Linolenate, Ceramide EOP, Sodium Gluconate, Disodium EDTA, Glycerin, Glyceryl Caprylate, Sodium Polyglutamate, Silica, Caprylyl Glycol, Potassium Sorbate, Butylene Glycol, Dimethicone, Hydroxycitronellal, Hexyl Cinnamal, Linalool, Alpha-Isomethyl Ionone, Limonene, Citronellol, Coumarin, Geraniol

Dicaprylyl Carbonate

Pentylene Glycol

Ascorbic Acid

Saccharide Isomerate

Haematococcus Pluvialis Extract

Hexapeptide-11

Palmitoyl Tripeptide-1

Ananas Sativus Fruit Extract

Glyceryl Acrylate/Acrylic Acid Copolymer

Sucrose Stearate

Polyglyceryl-10 Laurate

Cetearyl Olivate

Sorbitan Olivate

Sodium Citrate

Cetearyl Alcohol

Sodium Hydroxide

Lactobacillus Ferment

Leuconostoc/Radish Root Ferment Filtrate

Hydroxyacetophenone

CI 77491

Water, Propanediol, Dicaprylyl Carbonate, Glycerin, Pentylene Glycol, Sodium Hyaluronate, Hydrolyzed Sodium Hyaluronate, Glycine, Serine, Glutamic Acid, Aspartic Acid, Leucine, Alanine, Lysine, Arginine, Tyrosine, Phenylalanine, Proline, Threonine, Valine, Isoleucine, Histidine, Ascorbic Acid, Saccharide Isomerate, Haematococcus Pluvialis Extract, Ceramide NP, Tocopheryl Acetate, Tocopherol, Hexapeptide-11, Palmitoyl Tripeptide-1, Ananas Sativus Fruit Extract, Saccharomyces/Magnesium Ferment, Saccharomyces/Copper Ferment, Saccharomyces/Silicon Ferment, Butylene Glycol, Glyceryl Acrylate/Acrylic Acid Copolymer, Glyceryl Caprylate, Sucrose Stearate, Lecithin, Polyglyceryl-10 Laurate, Xanthan Gum, Cetearyl Olivate, Sorbitan Olivate, Sodium Citrate, Carbomer, Citric Acid, Cetearyl Alcohol, Sodium Hydroxide, Lactobacillus Ferment, Leuconostoc/Radish Root Ferment Filtrate, Hydroxyacetophenone, CI 77491

Reviews

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Alanine is an amino acid and is already found in the human body. Our skin uses alanine to build collagen, elastin, and keratin.

Arginine is a semi-essential amino acid. This just means our bodies can product a bit on its own, but sometimes needs a little boost from food sources.

It is a part of your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.

Here's an interesting thing about Arginine: your skin converts it into urea through the Krebs-Henseleit urea cycle. Urea is one of the most effective humectants your skin naturally produces.

A clinical study showed applying 2.5% arginine hydrochloride to atopic dermatitis skin showed significant urea levels in the stratum corneum and improved moisture in just four weeks.

Arginine is also a precursor to nitric oxide; nitric oxide improves microcirculation and supports wound healing and collagen synthesis.

One study found that an amino acid complex containing Arginine reduced skin irritation, improved hydration, and accelerated skin repair in clinical / in-vivo studies.

Arginine itself is an amino acid and not a fatty acid, oil, or ester. On its own, it's not a direct food source for Malassezia, or the yeast that causes fungal acne.

Aspartic Acid is an amino acid that our bodies produce naturally. It is an antioxidant.

Our body uses Aspartic Acid to help build collagen and elastin. It also plays a role in hydrating skin.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.

Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.

It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.

Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.

A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.

Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.

Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.

This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.

A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.

Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.

Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.

Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.

Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.

Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.

However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.

Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.

In skincare formulas, citric acid can:

While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.

Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.

Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.

However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's skin is unique, we recommend a patch test if you are unsure.

Glutamic Acid is an amino acid that is found in all living organisms. Our bodies use this to help nerve cells in the brain communicate with other cells.

In cosmetics, glutamic acid is a famous humectant. It draws water from the air to your skin, keeping your skin hydrated (like hyaluronic acid).

An in-vitro study from 2024 found glutamic acid to play a role in inhibiting inflammation and thus a potential skin-soothing ingredient.

Other studies show it to be have potential wound healing, skin barrier repair, and hair growth properties.

Glutamic acid has poor solubility in water and other solvents.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Glyceryl Caprylate comes from glycerin and caprylic acid. It is an emollient, co-emulsifier, and preservative booster.

Its short C8 fatty acid chain makes it behave differently from its longer-chain emollient cousins like Glyceryl Stearate. It feels more lightweight, fast-absorbing, and silky instead of rich and waxy.

As a co-emulsifier, its "head" and "tail" sit at the oil-water interface. But overall, the short C8 tail and not being water soluble means it doesn't really have the muscle to emulsify a formula on its own. That's why you'll often see it paired with a primary emulsifier like Cetearyl Glucoside.

Interestingly, Glyceryl Caprylate acts as a preservative booster. This is because its fatty-acid backbone disrupts microbial lipid membranes. It shows excellent activity against bacteria and yeast but is weaker against mold.

Typical concentrations range from 0.5-1% and this ingredient is generally non-irritating.

Because this ingredient has a C8 fatty acid chain, it is outside the range that the Malassezia yeast metabolizes (making it fungal acne safe).

Glycine is the smallest amino acid and a key building block of collagen. It's part if your skin's Natural Moisturizing Factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.

A study from 2022 found that an amino acid complex featuring taurine, arginine, and glycine significantly reduced skin irritation, improved redness, and accelerated the skin repair process.

Histidine is a semi-essential amino acid used by our bodies to create protein. It has humectant and skin conditioning properties.

Our bodies use histidine to create filaggrin - filaggrin is a structural protein that the skin uses in maintaining skin barrier.

One study found histidine and carnosine to be a dynamic duo for your skin:

Oral histidine has also been found to help with filaggrin-deficit skin disorders such as atopic dermatitis.

Why is it considered a semi-essential amino acid? This is because adults are able to create it but children must get it from their diet.

This ingredient is created by putting sodium hyaluronate through hydrolysis.

You might know this as 'mini' or 'ultra low-molecular weight' hyaluronic acid. The small molecule size means it is able to travel deeper in the skin.

According to studies, low molecular-weight hyaluronic acid can:

One study from 2011 found ultra-low weight HA to show pro-inflammatory properties. Another study from 2022 found it to downregulate UV-B induced inflammation.

Hydrolysis is a process of changing a molecule using water or enzymes.

This ingredient is water-soluble.

Isoleucine is an amino acid that helps reinforce our skin barrier. This amino acid plays a role in creating protein for the body.

Fun fact: Isoleucine is found in meat, fish, dairy, legumes, and nuts.

Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of phospholipids.

Thanks to its amphiphilic structure (water-loving head and oil-loving tail), it is a true multitasker:

It plays well with most ingredients and is typically used at 0.1-1%. However, concentrations up to 50% have been reported in moisturizers.

Leucine is a small amino acid and one of the building blocks your body uses to make proteins.

It's also naturally found in your skin as part of your Natural Moisturizing Factor (NMF). Your NMF is a mix of water-binding molecules that keeps the outer skin layer hydrated and flexible.

In skincare, it's mainly used as a skin conditioning ingredient that helps reinforce the same moisture-retention function.

You'll usually see it used at low percentages (generally under 5%) which is in line with how amino acids are used in cosmetics.

Lysine is an essential amino acid (your body cannot make it on its own). It has skin conditioning properties and one of the key players in collagen synthesis.

When your body creates collagen, lysine is basically the glue that holds everything together. It helps collagen fibers lock into each other and stay strong, with vitamin C being its trusty sidekick. Without enough lysine, this glue gets flimsy and less firm, resulting in less bouncy skin.

In skincare, lysine is mostly there to help keep your skin moisturized. It carries water through your skin's layers so everything stays plump.

So will putting lysine on your face create bouncier skin?

It's hard to say; most of the exciting collagen research on lysine comes from oral supplements or lab studies on mice. Further research is needed to truly understand what role topical lysine plays in skincare and your skin.

However, there's no harm in adding lysine to your routine as a supportive and hydrating ingredient.

Phenylalanine is an amino acid. It is a skin soothing and hydrating ingredient. Amino acids play a crucial role in wound healing and skin hydration.

This ingredient is also used to help even out skin tone due to its ability to disrupt the melanin production process.

Two structures of phenylalanine exist: L-phenylalanine and D-phenylalanine. L-phenylalanine is essential, this means our bodies cannot produce it naturally and we must get it from foods. Our bodies convert D-phenylalanine to neurotransmitters, and D-phenylalanine is found in our bodies naturally.

Some foods that contain L-phenylalanine include eggs, soybeans, beef, milk.

Proline is a non-essential amino acid, meaning your body can make it on its own. In skincare, it is a skin conditioning ingredient that keeps skin soft and hydrated.

It makes up about 23% of the collagen molecule (collagen is the protein responsible for keeping your skin firm) and is involved in your skin's natural hyaluronic acid production. When applied topically, proline can penetrate the skin fairly well due to its small molecular size.

Reviews of this ingredient have found it to be neither a dermal irritant nor a sensitizer.

Fun fact: Proline can be found in protein-rich foods like meat, fish, eggs, and dairy.

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

This ingredient comes from fermenting yeast (Saccharomyces) with copper ions.

Saccharomyces/Magnesium Ferment isn't fungal acne safe.

Saccharomyces/Silicon Ferment isn't fungal acne safe.

Serine is a non-essential amino acid (your body makes it on its own!). It is a major player in your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.

Serine is one of your NMF's most abundant components that works as a skin-identical humectant. Its hydroxyl group grabs onto water molecules to boost hydration without any heaviness or occlusion.

Research on a hydrogel with serine confirmed this serine got delivered to your stratum corneum and demonstrated enhanced skin moisturization.

Interestingly serine also helps your skin produce filaggrin, a protein that keeps your skin barrier strong and used to create collagen.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Threonine is an amino-acid. It helps hydrate the skin and has antioxidant benefits.

Our skin uses threonine for creating collagen and elastin. Humans are not able to create threonine and must get it through eating foods such as fish, lentils, poultry, sesame seeds, and more.

Tocopherol is a fat-soluble antioxidant known as Vitamin E.

You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.

Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.

It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.

This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.

Concentrations usually range from 0.1-1% in most leave-on products.

Tocopheryl Acetate is a stable, shelf-friendly form of vitamin E.

Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.

It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.

One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.

Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.

Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.

Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.

The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.

Most leave-on skincare keeps it at the lower end, often between 0.5-1%.

Tyrosine is one of the amino acids your body already uses as a protein building block. In skincare, it shows up as a skin-conditioning agent.

It's most notable for being the raw material that your skin's tyrosinase enzyme converts into melanin (skin pigment); this is why it's sometimes marketed as a "tan accelerator" in products.

However, the tanning claim is shaky. Lab studies on isolated skin cells show tyrosine can boost melanin production at fairly high concentrations but hasn't shown to speed up/deepen a tan when applied directly to skin in animal studies (up to 0.05%).

Finished cosmetic products use it at low levels (generally well under 1%). At these amounts, it's considered non-irritating and non-sensitizing based on repeat-use patch testing.

Allergy-wise, plain tyrosinase hasn't shown sensitization issues but a chemically modified relative called Oleoyl Tyrosine has had a handful of cases.

Valine is one of the essential amino acids (meaning your body can't make it on its own and has to get it from food).

In skincare, it's usually synthetically-made or pulled from plant proteins like soy.

It's one of the small building blocks that make up your skin's natural moisturizing factor (NMF), or the built-in system that helps skin hold onto water. So its main job in a formula is to give the skin gentle hydration and help it feel more comfortable.

Typical amounts are very tiny: roughly 0.00004%-0.5% in leave on products and up to 1% in rinse-off ones.

The Cosmetic Ingredient Review panel has looked at this ingredient and found no evidence of it being a skin irritant or allergen at cosmetic levels.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

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