Educational guide
CPC Scientific: Peptide and Oligo Company for CMC ...
Peptide & Oligo CDMO Services Research Peptides CPC Scientific is one of the premier custom peptide producers in the world and we are proud to offer consistently reliable, high-quality peptides directly to researchers. GMP Peptides Large-scale manufacturing ca
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Peptide & Oligo CDMO Services
Research Peptides
CPC Scientific is one of the premier custom peptide producers in the world and we are proud to offer consistently reliable, high-quality peptides directly to researchers.
GMP Peptides
Large-scale manufacturing capacity to support your GMP projects at every stage, from early discovery and late-phase development to full commercialization.
Oligonucleotides
We provide research-grade and clinical-grade oligonucleotide manufacturing services to our clients spanning from discovery to clinical phases.
Peptide-Oligo Conjugates
Our peptide-oligonucleotide conjugate (POC) services seamlessly integrates our peptide and oligonucleotide platforms.
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CPHI Korea
CPHI Korea
Seoul, South Korea | August 25-27, 2026
Seoul, South Korea | August 25-27, 2026
CPHI Korea is a dynamic meeting place where pharmaceutical suppliers, purchasers and decision makers get together for three days of uninterrupted business. Exhibiting companies showcase products from across the entire pharma supply chain.
38th European Peptide Symposium
38th European Peptide Symposium
Vienna, Austria | Sept. 6-11, 2026
Vienna, Austria | Sept. 6-11, 2026
The 38th EPS will explore the full spectrum of peptide science across synthetic methods, computational tools, and structural and conformational studies, with a special emphasis on material, biological, and therapeutic applications.
Stable Isotope-Labeled Peptides White Paper
Mass spectroscopy-based techniques have evolved as a powerful tool in proteomics. Stable isotope-labeled peptides (SIL peptides) are chemically and physically indistinguishable from their endogenous counterparts with respect to retention time, ionization efficiency, and fragmentation pathways.
May 27th, 2022
Triple-Stapled Peptide Macrocycle Case Study
While traditional stapling techniques have focused on reinforcing well-known secondary structures like α-helices and β-sheets, recent innovations have opened avenues for stabilizing non-helical and irregular conformations.
November 14th, 2024
RP-182 Analog: Synthesis & Click Cyclization
This white paper explores the click cyclization of RP-182, a promising cancer immunotherapy candidate. Our innovative approach showcases the use of copper catalysis to increase the macrocyclization efficiency of longer peptides under green reaction conditions.
January 31st, 2025
Peptide-Oligonucleotides Synthetic Strategies
Synthetic oligonucleotides constitute an important class of therapeutics developed to treat a variety of indications. Two main synthetic approaches exist for the conjugation of a peptide to an oligonucleotide: parallel and linear.
June 26th, 2023
How does SARS-CoV-2 spread so quickly?
May 26th, 2020
Minimal Protection Group Strategies for SPPS
Solid-phase peptide synthesis approaches require that the side chains of certain amino acids be protected from undesired reactivity during synthesis. The installation and removal of these protection groups results in a lower atom economy…
April 14th, 2023
Peptide PEGylation White Paper
PEGylation is now a well-established technique in the field of targeted drug delivery systems. As more PEGylated therapeutic agents receive FDA approval, more attention has been given to site-specific PEGylation of discrete or monodispersed PEG chains.
May 27th, 2022
Green Synthesis of Goserelin Impurity E
In this case study, we demonstrate the synthesis of a Goserelin peptide API impurity through a convergent peptide fragment strategy, expanding our approach to include the unprotected side chains of histidine, tryptophan, and arginine...
January 31st, 2025
Enabling Sustainable Large-Scale SPPS Through Process Innovations
Explore this case study on how our SPPS process optimizations have enabled multi-kilo delivery of a pharmaceutically relevant decapeptide within a challenging timescale, while improving environmental impact and production costs...
March 23rd, 2026
Why solid-phase synthesis?
Solid-phase peptide synthesis (SPPS) offers numerous advantages over liquid-phase peptide synthesis (LPPS) for the preparation and large-scale manufacturing of synthetic peptides. Except in the case of very short sequences (fewer than five amino acids), SPPS is generally faster, more efficient, and more economical.
November 14th, 2019
- Targeting the stringent response alters gene expression and extracellular vesicle RNA in Staphylococcus aureus
Mansour, S. C.; Wardell, S. J. T.; Baghela, A. S.; Blimkie, T.; Gill, E.; Straus, S. K.; Falsafi, R.; Pletzer, D.; Hancock, R. E. W. Microbiology Spectrum 2026, 14 (7).
DJK-5 (VQWRAIRVRVIR-NH2; all D amino acids) was synthesized by CPC Scientific using solid-phase 9-fluorenylmethoxy carbonyl (Fmoc) chemistry and purified to >95% purity using reverse-phase high-performance liquid chromatography.
- Proteolysis activity mapping and substrate discovery platform for identifying tumor-activated biosensors
Algov, I., Van Heest, A., Hopton, M., Liang, F., Holmes, A., Hao, L., Zhou, X. Nat Chem Biol (2026).
Fluorogenic peptide substrates were synthesized by CPC Scientific with fluorophore and quencher FAM and CPQ2 or Cy7 and QC1... An additional membrane-binding probe was synthesized by CPC Scientific for in vivo use, termed MBvivo-DNLGRAF (Suc-DGlu-DGlu-DGlu-DGlu-DGlu-DGlu-DGlu-DGlu-C6-Asp-Asn-Leu-Gly-Arg-Ala-Phe-Gly-DArg-DArg-DArg-DArg-DArg-DArg-DArg-DArg-DArg-C6-DLys(Cy5)-NH2).
- Scar-associated endothelial-stellate cellular crosstalk drives fibrosis resolution in MASH
Li, K.; Kumar, V.; To, T.; González-Domínguez, Á.; Huria, J.; Yu, M.; Cogliati, B.; Yashaswini, C. N.; Miller, M.; Branch, A. D.; et al. Cell Reports 2026, 45 (2), 116915.
The peptide-based probes (Table S2) were synthesized by CPC Scientific (Sunnyvale, CA) and reconstituted in dimethylformamide (DMF).
What Clients Say About Working With CPC Scientific
CPC Scientific has been our trusted provider of high-quality APIs for several years, consistently delivering exceptional reliability, technical expertise, and quality. Their contribution was instrumental in advancing a life-saving therapy. As a European biotech company, we rely on CPC Scientific’s expertise and dedication to support our long-term success.
CEO, Boutique European Biotechnology Company
CPC Scientific has been an essential CDMO partner throughout our peptide development journey, consistently delivering reliable, high-quality peptides. As a small Brazilian biotech focused on specialized disease areas, we value their fairness, transparency, and seamless collaboration. Their support plays a vital role in helping us bring our innovations to life.
Founder & CEO, Mid-Sized Brazilian Biotech Company
CPC Scientific has been an invaluable CRDMO partner in our research. One representative, in particular, has consistently gone above and beyond to ensure our complex peptide orders were delivered on time, ensuring we met key deadlines for PK and efficacy studies. Their exceptional customer service, responsiveness, and industry expertise have made a significant impact on our work. Even as a relatively new client, we’ve felt fully supported. Thank you, CPC Scientific, for your support of academic drug discovery research through outstanding service!
Faculty Member, Drug Discovery Researcher, and Director of R&D, U.S.-Based Academic Institution
CPC Scientific has been our trusted provider of high-quality APIs for several years, consistently delivering exceptional reliability, technical expertise, and quality. Their contribution was instrumental in advancing a life-saving therapy. As a European biotech company, we rely on CPC Scientific’s expertise and dedication to support our long-term success.
CEO, Boutique European Biotechnology Company
CPC Scientific has been an essential CDMO partner throughout our peptide development journey, consistently delivering reliable, high-quality peptides. As a small Brazilian biotech focused on specialized disease areas, we value their fairness, transparency, and seamless collaboration. Their support plays a vital role in helping us bring our innovations to life.
Founder & CEO, Mid-Sized Brazilian Biotech Company
CPC Scientific has been an invaluable CRDMO partner in our research. One representative, in particular, has consistently gone above and beyond to ensure our complex peptide orders were delivered on time, ensuring we met key deadlines for PK and efficacy studies. Their exceptional customer service, responsiveness, and industry expertise have made a significant impact on our work. Even as a relatively new client, we’ve felt fully supported. Thank you, CPC Scientific, for your support of academic drug discovery research through outstanding service!
Faculty Member, Drug Discovery Researcher, and Director of R&D, U.S.-Based Academic Institution
Trusted Peptide and Oligo Manufacturer
GMP Inspections by Various Authorities and Quality Organizations
Medtide Inc. Stock
Parent Company of CPC Scientific(HKEX: 03880)Parent Company of CPC Scientific
(HKEX: 03880)