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Coxir Intensive EGF Peptide Emulsion Versus Beauty Pie Youthbomb Breakthrough Repair Cream

Coxir Intensive EGF Peptide Emulsion Versus Beauty Pie Youthbomb Breakthrough Repair Cream This anti-aging moisturizer is formulated around Niacinamide and Sh-Oligopeptide-1 to soften the look of wrinkles. This barrier-repair moisturizer is formulated around N

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

Coxir Intensive EGF Peptide Emulsion Versus Beauty Pie Youthbomb Breakthrough Repair Cream

This anti-aging moisturizer is formulated around Niacinamide and Sh-Oligopeptide-1 to soften the look of wrinkles.

This barrier-repair moisturizer is formulated around Niacinamide and Bakuchiol to strengthen the skin barrier and soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Butylene Glycol

Caprylic/Capric Triglyceride

Helianthus Annuus Seed Oil

Butylene Glycol Dicaprylate/Dicaprate

Niacinamide

Sodium Hyaluronate

1,2-Hexanediol

Arachidyl Alcohol

Behenyl Alcohol

Arachidyl Glucoside

Cyclomethicone

Adenosine

Glycerin

Hydrogenated Lecithin

Sh-Oligopeptide-1

Copper Tripeptide-1

Glyceryl Stearate

PEG-100 Stearate

Polysorbate 60

Diisostearyl Malate

Dimethicone

Myrciaria Dubia Fruit Extract

Euterpe Oleracea Fruit Extract

Sorbitan Stearate

Allantoin

Xanthan Gum

Tocopheryl Acetate

Lonicera Japonica Flower Extract

Solanum Lycopersicum Fruit Extract

Lilium Tigrinum Extract

Nelumbo Nucifera Seed Extract

Chrysanthemum Indicum Flower Extract

Hydrolyzed Collagen

Acanthopanax Senticosus Root Extract

Punica Granatum Fruit Extract

Panax Ginseng Root Extract

Carthamus Tinctorius Flower Extract

Carbomer

Disodium EDTA

Arginine

Malva Sylvestris Flower Extract

Buddleja Davidii Extract

Thymus Vulgaris Extract

Camellia Sinensis Callus Culture Extract

Phaseolus Radiatus Meristem Cell Culture Extract

Panax Ginseng Callus Culture Extract

Ethylhexylglycerin

Pyrus Malus Leaf Extract

Theobroma Cacao Extract

Vanilla Planifolia Fruit Extract

Fragaria Chiloensis Fruit Extract

Prunus Persica Fruit Extract

Musa Sapientum Fruit Extract

Cocos Nucifera Oil

Prunus Domestica Fruit Extract

Water, Butylene Glycol, Caprylic/Capric Triglyceride, Helianthus Annuus Seed Oil, Butylene Glycol Dicaprylate/Dicaprate, Niacinamide, Sodium Hyaluronate, 1,2-Hexanediol, Arachidyl Alcohol, Behenyl Alcohol, Arachidyl Glucoside, Cyclomethicone, Adenosine, Glycerin, Hydrogenated Lecithin, Sh-Oligopeptide-1, Copper Tripeptide-1, Glyceryl Stearate, PEG-100 Stearate, Polysorbate 60, Diisostearyl Malate, Dimethicone, Myrciaria Dubia Fruit Extract, Euterpe Oleracea Fruit Extract, Sorbitan Stearate, Allantoin, Xanthan Gum, Tocopheryl Acetate, Lonicera Japonica Flower Extract, Solanum Lycopersicum Fruit Extract, Lilium Tigrinum Extract, Nelumbo Nucifera Seed Extract, Chrysanthemum Indicum Flower Extract, Hydrolyzed Collagen, Acanthopanax Senticosus Root Extract, Punica Granatum Fruit Extract, Panax Ginseng Root Extract, Carthamus Tinctorius Flower Extract, Carbomer, Disodium EDTA, Arginine, Malva Sylvestris Flower Extract, Buddleja Davidii Extract, Thymus Vulgaris Extract, Camellia Sinensis Callus Culture Extract, Phaseolus Radiatus Meristem Cell Culture Extract, Panax Ginseng Callus Culture Extract, Ethylhexylglycerin, Pyrus Malus Leaf Extract, Theobroma Cacao Extract, Vanilla Planifolia Fruit Extract, Fragaria Chiloensis Fruit Extract, Prunus Persica Fruit Extract, Musa Sapientum Fruit Extract, Cocos Nucifera Oil, Prunus Domestica Fruit Extract

Coco-Caprylate/Caprate

Hamamelis Virginiana Water

Bakuchiol

Potassium Azeloyl Diglycinate

Pentylene Glycol

Avena Sativa Kernel Extract

Polyglutamic Acid

Hydrolyzed Rice Protein

Sodium Hydroxide

Hydrolyzed Pea

Teprenone

Undaria Pinnatifida Extract

Tetrasodium Glutamate Diacetate

Sodium Benzoate

Phenethyl Alcohol

Harpagophytum Procumbens Root Extract

Sodium Carrageenan

Equisetum Arvense Extract

Glycyrrhiza Glabra Root Extract

Salix Alba Bark Extract

Maris Sal

Bacillus Ferment

Citric Acid

Potassium Sorbate

Alchemilla Vulgaris Extract

Water, Coco-Caprylate/Caprate, Niacinamide, Caprylic/Capric Triglyceride, 1,2-Hexanediol, Butylene Glycol, Glycerin, Hamamelis Virginiana Water, Arachidyl Alcohol, Glyceryl Stearate, PEG-100 Stearate, Bakuchiol, Dimethicone, Behenyl Alcohol, Potassium Azeloyl Diglycinate, Carbomer, Arachidyl Glucoside, Pentylene Glycol, Avena Sativa Kernel Extract, Polyglutamic Acid, Ethylhexylglycerin, Hydrolyzed Rice Protein, Sodium Hydroxide, Hydrolyzed Pea, Teprenone, Undaria Pinnatifida Extract, Tetrasodium Glutamate Diacetate, Sodium Benzoate, Phenethyl Alcohol, Harpagophytum Procumbens Root Extract, Sodium Carrageenan, Equisetum Arvense Extract, Glycyrrhiza Glabra Root Extract, Salix Alba Bark Extract, Maris Sal, Bacillus Ferment, Citric Acid, Potassium Sorbate, Alchemilla Vulgaris Extract

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Arachidyl Alcohol is a fatty alcohol made from the the arachidic acid found in peanut oil.

Despite having "alcohol" in the name, it is not related to denatured alcohol or ethanol.

This ingredient is a multitasker:

Just be sure to patch this ingredient if you have a peanut allergy (though this ingredient is highly processed and the allergenic proteins are typically removed).

This ingredient is a plant-based surfactant and emulsifier. It helps oil and water based ingredients mix evenly to improve formula stability without adding a "greasy" feel.

Behenyl Alcohol is a type of fatty alcohol (these are different from the drying, solvent alcohols).

Fatty Alcohols have hydrating properties and are most often used as an emollient or to thicken a product. They are usually derived from natural fats and oils; behenyl alcohol is derived from the fats of vegetable oils.

Emollients help keep your skin soft and hydrated by creating a film that traps moisture in.

In 2000, Behenyl Alcohol was approved by the US as medicine to reduce the duration of cold sores.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.

Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.

In practice, that translates to a long shelf life and a consistently elegant skin feel.

While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.

Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.

This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.

This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.

Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.

Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.

It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.

Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.

A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.

Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.

What it does:

Dimethicone comes in different viscosities:

Depending on the viscosity, dimethicone has different properties.

Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.

This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.

Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Glyceryl Stearate is made by reacting glycerin with stearic acid (typically sourced from plant oils like palm or coconut). It's an emulsifier, emollient, and mild occlusive.

Emulsifiers help ingredients like oil and water stay mixed so your formula stays nicely blended and uniform in texture.

This ingredient is typically used in concentrations between 1-10%. Studies have found it to be non-sensitizing, non-phototoxic, and non-photoallergenic.

A close cousin of this ingredient is Glyceryl Stearate SE ("self-emulsifying"). This just has a small amount of sodium or potassium stearate added so it can emulsify without a co-emulsifier.

Since this ingredient is an ester of a C18 fatty acid, it may not be fungal acne safe. The Malassezia yeast can potentially metabolize within the C11-C24 range.

Fun fact: The human body also creates Glyceryl Stearate naturally.

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Peg-100 Stearate is an emollient and emulsifier. As an emollient, it helps keep skin soft by trapping moisture in. On the other hand, emulsifiers help prevent oil and water from separating in a product.

PEGS are a hydrophilic polyether compound . There are 100 ethylene oxide monomers in Peg-100 Stearate. Peg-100 Stearate is polyethylene glycol ester of stearic acid.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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