Educational guide
COSRX Advanced Snail 96 Mucin Power Essence Versus AMPLE:N Peptide Shot Ampoule
COSRX Advanced Snail 96 Mucin Power Essence Versus AMPLE:N Peptide Shot Ampoule This hydrating essence is formulated around Snail Secretion Filtrate and Allantoin to hydrate skin and calm redness. This anti-aging ampoule is formulated around Niacinamide and Ac
This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.
COSRX Advanced Snail 96 Mucin Power Essence Versus AMPLE:N Peptide Shot Ampoule
This hydrating essence is formulated around Snail Secretion Filtrate and Allantoin to hydrate skin and calm redness.
This anti-aging ampoule is formulated around Niacinamide and Acetyl Hexapeptide-8 to soften the look of wrinkles.
What's inside
Key Ingredients
Benefits
Concerns
No concerns
Ingredients Side-by-side
Snail Secretion Filtrate
Betaine
Butylene Glycol
1,2-Hexanediol
Sodium Polyacrylate
Phenoxyethanol
Sodium Hyaluronate
Allantoin
Ethyl Hexanediol
Carbomer
Panthenol
Arginine
Water
Snail Secretion Filtrate, Betaine, Butylene Glycol, 1,2-Hexanediol, Sodium Polyacrylate, Phenoxyethanol, Sodium Hyaluronate, Allantoin, Ethyl Hexanediol, Carbomer, Panthenol, Arginine, Water
Glycerin
Dipropylene Glycol
Alcohol
PEG-32
Biosaccharide Gum-1
Niacinamide
Trehalose
Adenosine
Acetyl Hexapeptide-8
Hydrogenated Lecithin
Beta-Glucan
Dipotassium Glycyrrhizate
Helichrysum Arenarium Extract
Yeast Extract
Palmitoyl Pentapeptide-4
Pearl Extract
Dimethicone
PEG-60 Hydrogenated Castor Oil
Xanthan Gum
Titanium Dioxide
Sodium Palmitoyl Sarcosinate
Glyceryl Acrylate/Acrylic Acid Copolymer
Mica
Caramel
Agar
Calcium Alginate
Gellan Gum
Polysorbate 20
Propylene Glycol
Caprylyl Glycol
Glyceryl Caprylate
Phenylpropanol
Palmitoyl Oligopeptide
Lactic Acid
Polyvinyl Alcohol
Glycolic Acid
Parfum
Ethylhexylglycerin
Tetrasodium EDTA
Water, Glycerin, Butylene Glycol, Dipropylene Glycol, Alcohol, PEG-32, Biosaccharide Gum-1, Niacinamide, Trehalose, Adenosine, Acetyl Hexapeptide-8, Arginine, Panthenol, Hydrogenated Lecithin, Beta-Glucan, Dipotassium Glycyrrhizate, Helichrysum Arenarium Extract, Yeast Extract, Palmitoyl Pentapeptide-4, Pearl Extract, Dimethicone, PEG-60 Hydrogenated Castor Oil, 1,2-Hexanediol, Carbomer, Xanthan Gum, Titanium Dioxide, Sodium Palmitoyl Sarcosinate, Glyceryl Acrylate/Acrylic Acid Copolymer, Mica, Caramel, Agar, Calcium Alginate, Gellan Gum, Polysorbate 20, Propylene Glycol, Caprylyl Glycol, Glyceryl Caprylate, Phenylpropanol, Palmitoyl Oligopeptide, Lactic Acid, Polyvinyl Alcohol, Glycolic Acid, Phenoxyethanol, Parfum, Ethylhexylglycerin, Tetrasodium EDTA
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
Humectant, drawing moisture into the skin
Emollient, helping to soften skin
Solvent, dispersing and stabilizing formulas
Preservative booster, enhancing the antimicrobial activity of other preservatives
Arginine is a semi-essential amino acid. This just means our bodies can product a bit on its own, but sometimes needs a little boost from food sources.
It is a part of your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.
Here's an interesting thing about Arginine: your skin converts it into urea through the Krebs-Henseleit urea cycle. Urea is one of the most effective humectants your skin naturally produces.
A clinical study showed applying 2.5% arginine hydrochloride to atopic dermatitis skin showed significant urea levels in the stratum corneum and improved moisture in just four weeks.
Arginine is also a precursor to nitric oxide; nitric oxide improves microcirculation and supports wound healing and collagen synthesis.
One study found that an amino acid complex containing Arginine reduced skin irritation, improved hydration, and accelerated skin repair in clinical / in-vivo studies.
Arginine itself is an amino acid and not a fatty acid, oil, or ester. On its own, it's not a direct food source for Malassezia, or the yeast that causes fungal acne.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.
Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.
It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.
Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.
A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.
Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!