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Clinique Turnaround Overnight Revitalizing Moisturizer Versus Summer Fridays Rich Cushion Cream Ultra Plumping Moisturizer

Clinique Turnaround Overnight Revitalizing Moisturizer Versus Summer Fridays Rich Cushion Cream Ultra Plumping Moisturizer This smoothing night moisturizer is formulated around Squalane and Salicylic Acid to refine skin texture and brighten dull-looking skin.

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

Clinique Turnaround Overnight Revitalizing Moisturizer Versus Summer Fridays Rich Cushion Cream Ultra Plumping Moisturizer

This smoothing night moisturizer is formulated around Squalane and Salicylic Acid to refine skin texture and brighten dull-looking skin.

This barrier-repair moisturizer is formulated around Helianthus Annuus Seed Oil and Hyaluronic Acid to strengthen the skin barrier and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Isostearyl Palmitate

Cetyl Ricinoleate

Dimethicone

Butylene Glycol

Squalane

Glyceryl Stearate

PEG-100 Stearate

Cetyl Alcohol

Stearic Acid

Arginine

Sigesbeckia Orientalis Extract

Hordeum Vulgare Extract

Castanea Sativa Seed Extract

Cucumis Sativus Fruit Extract

Faex Extract

Rosmarinus Officinalis Extract

Trehalose

Salicylic Acid

Creatine

Ethylhexylglycerin

Propylene Glycol Dicaprate

Lecithin

Acetyl Glucosamine

Hydroxyethyl Urea

Petrolatum

Helianthus Annuus Seed Extract

Arginine Ferulate

Polysilicone-11

Tromethamine

Caprylyl Glycol

Sodium Rna

Tocopheryl Acetate

Glycerin

Phospholipids

Hexylene Glycol

Sodium Hyaluronate

Disodium Nadh

Micrococcus Lysate

Laurdimonium Hydroxypropyl Hydrolyzed Soy Protein

Xanthan Gum

Adenosine Phosphate

Carbomer

Ascorbyl Tocopheryl Maleate

Nordihydroguaiaretic Acid

Disodium EDTA

Sodium Metabisulfite

Sorbic Acid

Chlorphenesin

Potassium Sorbate

Phenoxyethanol

Water, Isostearyl Palmitate, Cetyl Ricinoleate, Dimethicone, Butylene Glycol, Squalane, Glyceryl Stearate, PEG-100 Stearate, Cetyl Alcohol, Stearic Acid, Arginine, Sigesbeckia Orientalis Extract, Hordeum Vulgare Extract, Castanea Sativa Seed Extract, Cucumis Sativus Fruit Extract, Faex Extract, Rosmarinus Officinalis Extract, Trehalose, Salicylic Acid, Creatine, Ethylhexylglycerin, Propylene Glycol Dicaprate, Lecithin, Acetyl Glucosamine, Hydroxyethyl Urea, Petrolatum, Helianthus Annuus Seed Extract, Arginine Ferulate, Polysilicone-11, Tromethamine, Caprylyl Glycol, Sodium Rna, Tocopheryl Acetate, Glycerin, Phospholipids, Hexylene Glycol, Sodium Hyaluronate, Disodium Nadh, Micrococcus Lysate, Laurdimonium Hydroxypropyl Hydrolyzed Soy Protein, Xanthan Gum, Adenosine Phosphate, Carbomer, Ascorbyl Tocopheryl Maleate, Nordihydroguaiaretic Acid, Disodium EDTA, Sodium Metabisulfite, Sorbic Acid, Chlorphenesin, Potassium Sorbate, Phenoxyethanol

Helianthus Annuus Seed Oil

Ethylhexyl Palmitate

Isopropyl Myristate

Betaine

Hyaluronic Acid

Citrullus Lanatus Fruit Extract

Pyrus Malus Fruit Extract

Lens Esculenta Fruit Extract

Simmondsia Chinensis Seed Oil

Persea Gratissima Oil

Carthamus Tinctorius Seed Oil

Saccharide Isomerate

Chamomilla Recutita Flower Extract

Bisabolol

Allantoin

Centella Asiatica Extract

Salicornia Herbacea Extract

Kappaphycus Alvarezii Extract

Caesalpinia Spinosa Fruit Extract

Resveratrol

Tetrahexyldecyl Ascorbate

Tocopherol

Panthenol

Sodium PCA

Sodium Lactate

Caprylic/Capric Triglyceride

Glyceryl Laurate

Palmitic Acid

Hydroxypropyl Cyclodextrin

Sodium Citrate

Glyceryl Stearate Citrate

Glyceryl Caprylate

Citric Acid

Sodium Hydroxide

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Sodium Benzoate

Water, Helianthus Annuus Seed Oil, Glycerin, Ethylhexyl Palmitate, Glyceryl Stearate, Isopropyl Myristate, Cetyl Alcohol, Betaine, Hyaluronic Acid, Citrullus Lanatus Fruit Extract, Pyrus Malus Fruit Extract, Lens Esculenta Fruit Extract, Simmondsia Chinensis Seed Oil, Persea Gratissima Oil, Carthamus Tinctorius Seed Oil, Squalane, Saccharide Isomerate, Chamomilla Recutita Flower Extract, Bisabolol, Allantoin, Centella Asiatica Extract, Salicornia Herbacea Extract, Kappaphycus Alvarezii Extract, Caesalpinia Spinosa Fruit Extract, Resveratrol, Tetrahexyldecyl Ascorbate, Tocopherol, Tocopheryl Acetate, Panthenol, Sodium PCA, Sodium Lactate, Caprylic/Capric Triglyceride, Ethylhexylglycerin, Glyceryl Laurate, Stearic Acid, Palmitic Acid, Hydroxypropyl Cyclodextrin, Caprylyl Glycol, Sodium Citrate, Glyceryl Stearate Citrate, Glyceryl Caprylate, Potassium Sorbate, Citric Acid, Sodium Hydroxide, Xanthan Gum, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Sodium Benzoate

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Cetyl Alcohol is a fatty alcohol. Fatty Alcohols are most often used as an emollient or to thicken a product.

Its main roles are:

Though it has "alcohol" in the name, it is not related to denatured alcohol or ethyl alcohol.

The FDA allows products labeled "alcohol-free" to have fatty alcohols.

This ingredient may not be fungal acne safe. It is a primary fatty alcohol with a chain length above 12 carbons. A study from 2019 show Malassezia can feed on fatty alcohols in this range, so it may trigger fungal acne in those prone to it.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Glyceryl Stearate is made by reacting glycerin with stearic acid (typically sourced from plant oils like palm or coconut). It's an emulsifier, emollient, and mild occlusive.

Emulsifiers help ingredients like oil and water stay mixed so your formula stays nicely blended and uniform in texture.

This ingredient is typically used in concentrations between 1-10%. Studies have found it to be non-sensitizing, non-phototoxic, and non-photoallergenic.

A close cousin of this ingredient is Glyceryl Stearate SE ("self-emulsifying"). This just has a small amount of sodium or potassium stearate added so it can emulsify without a co-emulsifier.

Since this ingredient is an ester of a C18 fatty acid, it may not be fungal acne safe. The Malassezia yeast can potentially metabolize within the C11-C24 range.

Fun fact: The human body also creates Glyceryl Stearate naturally.

Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.

This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.

Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.

You'll often find this ingredient used with other preservatives.

Squalane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).

It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.

This is due to how structurally similar it is to what your skin already produces.

Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.

Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.

No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).

Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.

This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Though squalane is often called an oil, it’s technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.

The term “oil-free” isn’t regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.

Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.

A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.

The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.

Stearic Acid is a fatty acid that is already found in your skin. It's one of the free fatty acids that works alongside ceramides and cholesterols to maintain your barrier.

In cosmetics, it is a multitasker:

Safety-wise, the CIR Expert Panel has concluded it to be safe in cosmetics when formulated to be non-irritating and non-sensitizing.

Free stearic acid is a C18 fatty acid that the Malassezia yeast can substrate, so this ingredient may not be fungal acne safe.

Tocopheryl Acetate is a stable, shelf-friendly form of vitamin E.

Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.

It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.

One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.

Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.

Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.

The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.

Most leave-on skincare keeps it at the lower end, often between 0.5-1%.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

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Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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