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Biotin: What It Is, Benefits and Dosage

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This essential nutrient helps convert food into energy, but don’t expect wonders for your nails and hair

Image content: This image is available to view online.

View image online (https://assets.clevelandclinic.org/transform/c994c628-d179-4fc8-83e6-45d4c2037a05/biotin-rich-foods-1135301923)

Raw liver, pork, salmon and eggs, and almonds

If you do a web search for biotin, probably the first thing that pops up is a laundry list of supplements. Most of which claim to give you long, shiny locks and super-strong nails.

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But biotin does much more for your body than those supplements claim. And enhancing your hair and nails isn’t necessarily at the top of the list. What’s more, you probably don’t need to shell out for those bottles of biotin to reap the benefits.

Registered dietitian Courtney Delpra, RD, LD, explains the possible benefits of biotin — both from the foods you eat and from supplements.

Biotin is a B vitamin (B7, to be specific) that’s important for many body functions.

Biotin helps metabolize food — turning food into energy. And many people swear that biotin has improved their hair, skin and nail health, too.

B vitamins, including biotin are water-soluble. That means that your body doesn’t hang on to more of it than you need. But that doesn’t mean you can’t overdo it on biotin. More on that in a bit.

Biotin is an essential vitamin, which means you can’t live without it.

Biotin plays an important role in giving you fuel to go about your day. That’s because one of its top benefits is that it helps convert carbohydrates, fats and proteins into energy.

How?

“Biotin is a co-factor for enzymes that help to break down fatty acids, glucose and amino acids,” Delpra explains. “We need certain enzymes to break down the foods we eat so we can metabolize them. And those enzymes don’t work properly without biotin.”

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Biotin is also involved in maintaining healthy nervous system function. And it helps with gene functions.

Perhaps biotin’s biggest claim to fame is that it’s gotten quite a reputation in the beauty industry in promoting healthy skin, hair and nails.

That’s because biotin deficiency (not having enough biotin) can lead to issues like:

  • Brittle nails
  • Hair loss
  • Red, scaly rash

The trouble with that thinking?

“Biotin deficiency is rare in the U.S.,” Delpra clarifies. “So, if you have thinning hair or brittle nails, it’s probably not due to a biotin deficiency. There’s usually another health condition causing these problems, such as iron deficiency or a thyroid issue.”

OK, you’re thinking, maybe I don’t have a biotin deficiency necessarily. But maybe more biotin can still give me shining locks, right?

Ehhh...

“No studies have proven that biotin supplements will change the appearance of your hair, skin or nails,” Delpra shares. “But some people will tell you that taking a biotin supplement helps them boost hair and nail growth.”

Most people get adequate biotin through a healthy diet. Recommended daily intakes for biotin are as follows:

  • Under 6 months: 5 micrograms (mcg)
  • 7 to 12 months: 6 mcg
  • 1 to 3 years: 8 mcg
  • 4 to 8 years: 12 mcg
  • 9 to 13 years: 20 mcg
  • 14 to 18 years: 25 mcg
  • 19 and older: 30 mcg
  • Pregnant: 30 mcg
  • Lactating: 35 mcg

That’s much (much) less than the biotin content you’ll find in some common supplements.

Adult daily multivitamins and prenatal vitamins typically contain 100% of your recommended daily value for biotin. Other supplements, like “super B” vitamin formulations or vitamins that promote hair and nail growth can contain a lot more. We’re talking in the neighborhood of 10,000% of your daily value.

The good news is that most people get all the biotin they need from a healthy diet.

“Biotin is in many of the foods we eat,” Delpra points out. “And it’s always better to get your vitamins and minerals through a balanced diet rather than supplements.”

Biotin is found mainly in sources of protein. Foods like liver, eggs, salmon, pork, nuts and seeds are good sources.

Biotin supplements can have some mild side effects.

"When starting supplementation, always speak with your doctor,” Delpra recommends. “Biotin supplements and B-complex vitamins are safe for most people, though they may cause a slightly upset stomach.”

The bigger trouble?

Taking supplements that contain biotin can interfere with the accuracy of certain medical tests, like thyroid function tests, heart disease screenings and even tests to determine if you’re having a heart attack.

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Tell your healthcare provider if you’re taking any supplements that contain (or could contain) biotin.

More isn’t always better. Don’t take more than the dosage listed on the package and stop taking biotin if you notice side effects.

You can get your fill of biotin even without a supplement. In fact, most people do.

“Healthy food and proper hydration will help you feel and look your best,” Delpra advises.

What’s more, a healthy diet makes sure you’ll get your fill of other nutrients that fuel your body. Like healthy fats, protein, vitamins, minerals and fiber.

If you’re concerned that you’re not getting enough biotin in your diet, talk with a healthcare provider. They can test you for deficiencies and recommend strategies to help you live your healthiest life.

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by Dr. Usman | Dec 4, 2023 | Research Contents: Protein and Peptide Structural Elucidation B7-33 Peptide Synthesis and Structural Modification B7-33 and Activation of pERK Pathway B7-33 Peptide and Preeclampsia B7-33 Peptide and Vasoprotection B7-33 Peptide and Anti-Fibrosis B7-33 Peptide as Coating Material In Summary References Featured Product

Source: biotechpeptides.com ↗

Research Implications of B7-33:

Antifibrotic Potential: Fibrosis (scarring) occurs following significant tissue damage, as the cells knit back together in an irregular consistency to the surrounding tissues. Researchers suggest internal fibrosis may be a significant factor in chronic inflammatory diseases. Chronic liver, heart, or lung disease fibrosis is speculated to be the leading cause of organ failure. It has been suggested that controlling this unorganized tissue regeneration may prevent organ failure. A study on H2-relaxin proteins suggest their potential to reduce fibrosis following an ischemic injury to the heart. The peptide appeared to induce an immediate vasodilatory effect in the heart that might lead to a speculated reduction in long-term scarring. A study performed on rat models suggests that exposure to B7-33 reduced scarring by approximately 50% following significant tissue damage. This speculated reduction in fibrosis might eventually lead to improved cardiac function with lesser long-term complications associated with heart failure. Blood Vessel Protection and Preeclampsia: Researchers suggest that B7-33 possesses vasoprotective potential, comparative to Relaxin-2 (Serelaxin) against long-term scarring and endothelial dysfunction. It appears to do this through the activation of bradykinin-mediated relaxation of arteries that is endothelium-dependent. B7-33 might be more selective in its action as compared to Serelaxin. Preeclampsia is considered to be a common complication of pregnancy that may prove life-threatening to the mother and the fetus. It is characterized in part by high blood pressure in the mother and reduced fetal weight. A recent study provided data to suggest that B7-33, by stimulating RXFP-1 receptors, may lead to enhanced Vascular Endothelial Growth Factor (VEGF) production. VEGF might stimulate the production of the cytotrophoblast cells in the fetus, which are speculated to be responsible for developing blood flow from mother to fetus. B7-33 might help improve the fetus’s survival by prolonging the speculated duration of pregnancy in cases of premature delivery.

Source: biotechpeptides.com ↗
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Peptide Therapy Guide Editorial Team

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