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Biossance Squalane + Vitamin C Rose Oil Versus SkinBetter Science AlphaRet Overnight Cream

Biossance Squalane + Vitamin C Rose Oil Versus SkinBetter Science AlphaRet Overnight Cream This brightening oil is formulated around Squalane and Tetrahexyldecyl Ascorbate to brighten dull-looking skin and hydrate skin. This anti-aging night moisturizer is for

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

Biossance Squalane + Vitamin C Rose Oil Versus SkinBetter Science AlphaRet Overnight Cream

This brightening oil is formulated around Squalane and Tetrahexyldecyl Ascorbate to brighten dull-looking skin and hydrate skin.

This anti-aging night moisturizer is formulated around Glycolic Acid and Niacinamide to soften the look of wrinkles and refine skin texture.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Squalane

Tetrahexyldecyl Ascorbate

Caprylic/Capric Triglyceride

Pistacia Lentiscus Gum

Rosa Damascena Flower Extract

Geraniol

Citronellol

Squalane, Tetrahexyldecyl Ascorbate, Caprylic/Capric Triglyceride, Pistacia Lentiscus Gum, Rosa Damascena Flower Extract, Geraniol, Citronellol

Water

Sodium Glycolate

Glycolic Acid

Cetearyl Olivate

Pentylene Glycol

Cyclopentasiloxane

Isohexadecane

Sorbitan Olivate

Glycerin

Ceresin

Glycol Palmitate

Butylene Glycol

Niacinamide

Methyl Gluceth-20

Ethyl Lactyl Retinoate

Palmitoyl Tripeptide-1

Palmitoyl Tetrapeptide-7

Ceramide NP

Hyaluronic Acid

Ubiquinone

Tocopherol

Bisabolol

Tocopheryl Acetate

Superoxide Dismutase

Butyrospermum Parkii Butter

Allantoin Glycyrrhetinic Acid

Sodium PCA

Panthenol

Camellia Sinensis Leaf Extract

Portulaca Oleracea Extract

Linoleic Acid

Cholesterol

Linolenic Acid

Magnesium Aluminum Silicate

Dimethyl Isosorbide

Dimethicone

Glyceryl Stearate

PEG-100 Stearate

Steareth-2

Hydroxyethylcellulose

Acacia Senegal Gum

Xanthan Gum

Hydrated Silica

Carbomer

Polysorbate 20

Tromethamine

Disodium EDTA

Ethylhexylglycerin

Phenoxyethanol

CI 77891

Water, Sodium Glycolate, Glycolic Acid, Cetearyl Olivate, Pentylene Glycol, Cyclopentasiloxane, Isohexadecane, Sorbitan Olivate, Tetrahexyldecyl Ascorbate, Glycerin, Ceresin, Glycol Palmitate, Butylene Glycol, Niacinamide, Squalane, Methyl Gluceth-20, Ethyl Lactyl Retinoate, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Ceramide NP, Hyaluronic Acid, Ubiquinone, Tocopherol, Bisabolol, Tocopheryl Acetate, Superoxide Dismutase, Butyrospermum Parkii Butter, Allantoin Glycyrrhetinic Acid, Sodium PCA, Panthenol, Camellia Sinensis Leaf Extract, Portulaca Oleracea Extract, Linoleic Acid, Cholesterol, Linolenic Acid, Magnesium Aluminum Silicate, Dimethyl Isosorbide, Dimethicone, Glyceryl Stearate, PEG-100 Stearate, Steareth-2, Hydroxyethylcellulose, Acacia Senegal Gum, Xanthan Gum, Hydrated Silica, Carbomer, Polysorbate 20, Tromethamine, Disodium EDTA, Ethylhexylglycerin, Phenoxyethanol, CI 77891

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Squalane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).

It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.

This is due to how structurally similar it is to what your skin already produces.

Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.

Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.

No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).

Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.

This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Though squalane is often called an oil, it’s technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.

The term “oil-free” isn’t regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.

Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.

A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.

The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.

Tetrahexyldecyl Ascorbate (THD) is a stable and oil-soluble form of Vitamin C.

THD is special in that it has the ability to travel deeper into skin than traditional ascorbic acid while maintaining the same skin benefits (double win!).

Because it’s oil-soluble, THD dives deep into your skin’s fatty layers (think ceramides and cholesterol) to fight off the kind of free radicals that mess with your skin barrier. This makes it a great pair with water-based vitamin C (ascorbic acid) that mainly works on the surface.

Even at just 0.1%, THD is already showing great antioxidant activity. When used up to 2%, it helps keep your skin happy and calm, especially when it’s stressed from pollution or sun.

Want to fade dark spots or tackle hyperpigmentation? You’ll want 5% or more. Pairing it with brightening buddies like niacinamide or licorice root gives even better results. One study even used 30% THD with other brighteners and saw real results on stubborn discoloration, even in melasma-prone skin.

A note on THD: It’s has a slightly silky, oily texture and usually shows up colorless or pale yellow (though the exact shade can vary by supplier).

While you can sneak it into water-based formulas, it really shines when paired with silicones or oils, which help your skin soak it up better.

THD is pretty stable, but it’s still vulnerable to degradation like ascorbic acid. Too much light or heat (above 113°F / 45°C) can break it down over time. Go for dark and opaque packaging that keeps it safe and shady!

Read more about other types of Vitamin C:

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About the author

Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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