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Biossance Squalane + Tea Tree Cleansing Gel Versus Biossance Squalane + Amino Aloe Gentle Cleanser

Biossance Squalane + Tea Tree Cleansing Gel Versus Biossance Squalane + Amino Aloe Gentle Cleanser This mild gel cleanser is mild enough to cleanse without leaving skin feeling tight or stripped. This mild gel cleanser is made to cleanse without leaving your s

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

Biossance Squalane + Tea Tree Cleansing Gel Versus Biossance Squalane + Amino Aloe Gentle Cleanser

This mild gel cleanser is mild enough to cleanse without leaving skin feeling tight or stripped.

This mild gel cleanser is made to cleanse without leaving your skin tight or dry.

What's inside

Key Ingredients

No key ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Cocamidopropyl Hydroxysultaine

Aloe Barbadensis Leaf Juice

Glycerin

Sodium Cocoyl Isethionate

Disodium Coco-Glucoside Citrate

Squalane

Cocoyl Proline

Melaleuca Alternifolia Leaf Oil

Sodium Levulinate

Hydrolyzed Pea Protein

Lavandula Angustifolia Oil

Medicago Sativa Leaf Extract

Magnesium Chloride

Potassium Sorbate

Sodium Gluconate

Caramel

Citric Acid

Linalool

Water, Cocamidopropyl Hydroxysultaine, Aloe Barbadensis Leaf Juice, Glycerin, Sodium Cocoyl Isethionate, Disodium Coco-Glucoside Citrate, Squalane, Cocoyl Proline, Melaleuca Alternifolia Leaf Oil, Sodium Levulinate, Hydrolyzed Pea Protein, Lavandula Angustifolia Oil, Medicago Sativa Leaf Extract, Magnesium Chloride, Potassium Sorbate, Sodium Gluconate, Caramel, Citric Acid, Linalool

Moringa Oleifera Leaf Extract

Rosmarinus Officinalis Leaf Oil

Cymbopogon Schoenanthus Oil

Pelargonium Graveolens Oil

Salvia Sclarea Oil

Medicago Sativa Extract

Citral

Citronellol

Water, Aloe Barbadensis Leaf Juice, Cocamidopropyl Hydroxysultaine, Glycerin, Sodium Cocoyl Isethionate, Disodium Coco-Glucoside Citrate, Squalane, Cocoyl Proline, Moringa Oleifera Leaf Extract, Rosmarinus Officinalis Leaf Oil, Cymbopogon Schoenanthus Oil, Pelargonium Graveolens Oil, Salvia Sclarea Oil, Hydrolyzed Pea Protein, Medicago Sativa Extract, Sodium Levulinate, Caramel, Magnesium Chloride, Potassium Sorbate, Sodium Gluconate, Citric Acid, Citral, Citronellol, Linalool

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Aloe Barbadensis Leaf Juice is the filtered, stabilized liquid pressed from the inner gel of the aloe vera leaf.

In cosmetics, it shows up as either soothing active or a water-replacement base. It is roughly 98-99% water and the last 1-2% is an interesting mix of polysaccharides, amino acids, vitamins, minerals, and enzymes.

The polysaccharides do most of the work: they bind water at the skin surface for a light, non-greasy hydration boost. And one of the polysaccharides, glycomannan, is linked to fibroblast stimulation + collagen synthesis. This is also why aloe has such a long track record in wound and burn healing.

This ingredient is also calming with anti-inflammatory and mild antimicrobial activity, making it a great pick for sensitive, irritated, or post-sun skin.

Realistic expectations matter though; the solid evidence is mostly limited to hydration, soothing, and wound support. Deeper claims about anti-aging or sun protection are not well backed, and science reviews note it does not prevent radiation-induced skin injury.

Because it plays well with almost everything, it's commonly used as a base alongside other actives like niacinamide or vitamin C.

Typical usage concentrations range from 0.5% (where hydration benefits already show up) all the way to 90%+ (where it replaces water as the main base).

The safety for this ingredient is well-establish as well. Overall, this is a great supporting ingredient for those who want a boost in hydration.

We don't have a description for Caramel yet.

Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.

Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.

However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.

Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.

In skincare formulas, citric acid can:

While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.

Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.

Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.

However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's skin is unique, we recommend a patch test if you are unsure.

Cocamidopropyl Hydroxysultaine is a synthetic cleansing agent, though it is derived from coconut oil.

It is used to enhance the texture of products by boosting lather and thickening the texture. As a cleanser, Cocamidopropyl Hydroxysultaine is mild.

We don't have a description for Cocoyl Proline yet.

We don't have a description for Disodium Coco-Glucoside Citrate yet.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Hydrolyzed pea protein has skin conditioning and emollient properties. It is created by cutting protein fragments (peptides) into smaller pieces.

According to a manufacturer, this size of this ingredient makes it easy to be absorbed into skin where they strengthen the skin barrier, improve moisture retention, and improve signs of irritation.

One study that included pea proteins in a topical product reported improved atopic dermatitis symptom scores while a patent containing this ingredient suggests this ingredient to support hydration-related pathways in the skin.

Linalool is a fragrance and helps add scent to products. It's derived from common plants such as cinnamon, mint, citrus, and lavender.

Like Limonene, this ingredient oxidizes when exposed to air. Oxidized linalool can cause allergies and skin sensitivity.

This ingredient has a scent that is floral, spicy tropical, and citrus-like.

Magnesium chloride is a mineral salt made from magnesium and chloride. It is mainly used to control product stability and texture in cosmetics.

This ingredient can also play a role in soothing the skin and supporting normal skin function.

Magnesium chloride is water-soluble, generally well tolerated, and does not act as a strong “active” ingredient on its own.

Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.

This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.

Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.

You'll often find this ingredient used with other preservatives.

Sodium cocoyl isethionate is a natural ingredient from coconut oil. It is an ultra gentle cleanser that gives a nice foam without drying the skin or impacting the skin barrier.

The amount of foam created depends on the amount of sodium cocoyl isethionate used in the product.

This ingredient also helps improve the spreadability of a product.

This ingredient hasn’t been shown in studies to feed fungal acne yeast.

This is the synthetic salt of gluconic acid, a form of PHA and mild exfoliant.

It is mainly used to stabilize oil and butter formulations from going bad. Sodium gluconate is a humectant, pH regulator, and chelating agent.

Chelating agents help neutralize unwanted metals from affecting the formulation.

Sodium gluconate is water-soluble.

Sodium levulinate is the a sodium salt of Levulinic Acid. Oncedissolved in an aqueous solution, the two ingredients become identical. It is usually derived from renewable plant sources like corn starch or sugarcane.

In skincare, it mostly acts as a skin conditioning agent that keeps skin soft and hydrated. It also acts as a preservative booster by inhibiting the growth of mold, yeast, and bacteria.

It's often paired with Sodium Anisate as the two create a broad-spectrum preservative system that is popular in "natural" formulations.

This ingredient is water-soluble.

The CIR Expert Panel for Cosmetic Ingredient Safety has concluded this ingredient to be non-irritated and there are no restrictions for use in EU cosmetics. The FDA also allows this ingredient to be used as a food-grade flavoring agent.

Squalane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).

It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.

This is due to how structurally similar it is to what your skin already produces.

Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.

Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.

No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).

Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.

This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Though squalane is often called an oil, it’s technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.

The term “oil-free” isn’t regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.

Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.

A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.

The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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About the author

Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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