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Biossance Squalane + Omega Repair Cream Versus Murad Nutrient-Charged Water Gel

Biossance Squalane + Omega Repair Cream Versus Murad Nutrient-Charged Water Gel This barrier-repair moisturizer is formulated around Squalane and Ceramide NP to strengthen the skin barrier and hydrate skin. This barrier-repair moisturizer is formulated around

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

Biossance Squalane + Omega Repair Cream Versus Murad Nutrient-Charged Water Gel

This barrier-repair moisturizer is formulated around Squalane and Ceramide NP to strengthen the skin barrier and hydrate skin.

This barrier-repair moisturizer is formulated around Saccharide Isomerate and Ceramide NP to strengthen the skin barrier and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Squalane

Glycerin

Caprylic/Capric Triglyceride

Isoamyl Laurate

Butyrospermum Parkii Butter

Sorbitan Olivate

Cetearyl Olivate

Ceramide NP

Jojoba Esters

Sodium Hyaluronate

Euterpe Oleracea Sterols

Linoleic Acid

Oleic Acid

Linolenic Acid

Ethyl Linoleate

Tocopherol

Isoamyl Cocoate

Cetyl Palmitate

Sorbitan Palmitate

Cetearyl Alcohol

Ethylhexylglycerin

Carbomer

Sodium Hydroxide

Phenoxyethanol

Sodium Gluconate

Water, Squalane, Glycerin, Caprylic/Capric Triglyceride, Isoamyl Laurate, Butyrospermum Parkii Butter, Sorbitan Olivate, Cetearyl Olivate, Ceramide NP, Jojoba Esters, Sodium Hyaluronate, Euterpe Oleracea Sterols, Linoleic Acid, Oleic Acid, Linolenic Acid, Ethyl Linoleate, Tocopherol, Isoamyl Cocoate, Cetyl Palmitate, Sorbitan Palmitate, Cetearyl Alcohol, Ethylhexylglycerin, Carbomer, Sodium Hydroxide, Phenoxyethanol, Sodium Gluconate

Dimethicone

Propanediol

Polymethylsilsesquioxane/Silica Crosspolymer

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Isononyl Isononanoate

Saccharide Isomerate

Hydroxyethyl Urea

Ceramide AP

Ceramide EOP

Sh-Oligopeptide-1

Sh-Oligopeptide-2

Sh-Polypeptide-1

Sh-Polypeptide-9

Sh-Polypeptide-11

Saccharomyces/Zinc Ferment

Saccharomyces/Copper Ferment

Saccharomyces/Magnesium Ferment

Saccharomyces/Iron Ferment

Saccharomyces/Silicon Ferment

Leuconostoc/Radish Root Ferment Filtrate

Bacillus

Trehalose

Taurine

Serine

Tocopheryl Acetate

Calcium Pantothenate

Niacinamide

Phytantriol

Acetyl Glutamine

Urea

Cholesterol

Yeast Amino Acids

Phytosphingosine

Inositol

Betaine

Lecithin

Sodium Ascorbyl Phosphate

Pyridoxine Hcl

Sucrose

Algin

Pullulan

Maltodextrin

Polysilicone-11

Glyceryl Polyacrylate

Decyl Glucoside

Pentylene Glycol

Hexylene Glycol

Caprylyl Glycol

Butylene Glycol

Ethylhexyl Isononanoate

Polyisobutene

Silica

Sodium Starch Octenylsuccinate

PEG-7 Trimethylolpropane Coconut Ether

Trisodium Ethylenediamine Disuccinate

Disodium Phosphate

Potassium Phosphate

Xanthan Gum

Sodium Lauroyl Lactylate

1,2-Hexanediol

Parfum

CI 17200

CI 14700

Water, Dimethicone, Glycerin, Propanediol, Polymethylsilsesquioxane/Silica Crosspolymer, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Isononyl Isononanoate, Saccharide Isomerate, Hydroxyethyl Urea, Ceramide NP, Ceramide AP, Ceramide EOP, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-9, Sh-Polypeptide-11, Saccharomyces/Zinc Ferment, Saccharomyces/Copper Ferment, Saccharomyces/Magnesium Ferment, Saccharomyces/Iron Ferment, Saccharomyces/Silicon Ferment, Leuconostoc/Radish Root Ferment Filtrate, Bacillus, Trehalose, Taurine, Serine, Tocopheryl Acetate, Calcium Pantothenate, Niacinamide, Phytantriol, Acetyl Glutamine, Urea, Cholesterol, Yeast Amino Acids, Phytosphingosine, Inositol, Betaine, Lecithin, Sodium Ascorbyl Phosphate, Sodium Hyaluronate, Pyridoxine Hcl, Sucrose, Algin, Pullulan, Maltodextrin, Polysilicone-11, Glyceryl Polyacrylate, Decyl Glucoside, Pentylene Glycol, Hexylene Glycol, Caprylyl Glycol, Butylene Glycol, Ethylhexyl Isononanoate, Polyisobutene, Silica, Sodium Starch Octenylsuccinate, PEG-7 Trimethylolpropane Coconut Ether, Trisodium Ethylenediamine Disuccinate, Disodium Phosphate, Potassium Phosphate, Carbomer, Xanthan Gum, Sodium Lauroyl Lactylate, 1,2-Hexanediol, Phenoxyethanol, Ethylhexylglycerin, Parfum, CI 17200, CI 14700

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.

Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.

It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.

Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.

A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.

Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.

Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.

This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.

A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.

Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.

Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.

Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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