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Biossance Squalane + Omega Repair Cream Versus Clinique Moisture Surge 100H Auto-Replenishing Hydrator

Biossance Squalane + Omega Repair Cream Versus Clinique Moisture Surge 100H Auto-Replenishing Hydrator This barrier-repair moisturizer is formulated around Squalane and Ceramide NP to strengthen the skin barrier and hydrate skin. This barrier-repair moisturize

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

Biossance Squalane + Omega Repair Cream Versus Clinique Moisture Surge 100H Auto-Replenishing Hydrator

This barrier-repair moisturizer is formulated around Squalane and Ceramide NP to strengthen the skin barrier and hydrate skin.

This barrier-repair moisturizer is formulated around Sodium Hyaluronate and Aloe Barbadensis Leaf Extract to strengthen the skin barrier and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Squalane

Glycerin

Caprylic/Capric Triglyceride

Isoamyl Laurate

Butyrospermum Parkii Butter

Sorbitan Olivate

Cetearyl Olivate

Ceramide NP

Jojoba Esters

Sodium Hyaluronate

Euterpe Oleracea Sterols

Linoleic Acid

Oleic Acid

Linolenic Acid

Ethyl Linoleate

Tocopherol

Isoamyl Cocoate

Cetyl Palmitate

Sorbitan Palmitate

Cetearyl Alcohol

Ethylhexylglycerin

Carbomer

Sodium Hydroxide

Phenoxyethanol

Sodium Gluconate

Water, Squalane, Glycerin, Caprylic/Capric Triglyceride, Isoamyl Laurate, Butyrospermum Parkii Butter, Sorbitan Olivate, Cetearyl Olivate, Ceramide NP, Jojoba Esters, Sodium Hyaluronate, Euterpe Oleracea Sterols, Linoleic Acid, Oleic Acid, Linolenic Acid, Ethyl Linoleate, Tocopherol, Isoamyl Cocoate, Cetyl Palmitate, Sorbitan Palmitate, Cetearyl Alcohol, Ethylhexylglycerin, Carbomer, Sodium Hydroxide, Phenoxyethanol, Sodium Gluconate

Dimethicone

Butylene Glycol

Trisiloxane

Trehalose

Saccharomyces Lysate Extract

Aloe Barbadensis Leaf Extract

Aloe Barbadensis Leaf Water

Silybum Marianum Extract

Camellia Sinensis Leaf Extract

Aloe Barbadensis Leaf Polysaccharides

Sorbitol

Sodium Polyaspartate

Caffeine

Thermus Thermophillus Ferment

Lactobacillus Ferment Lysate

Palmitoyl Hexapeptide-12

Caprylyl Glycol

Sucrose

Hydroxyethyl Urea

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Oleth-10

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Saccharide Isomerate

Hydrogenated Lecithin

Tromethamine

Glyceryl Polymethacrylate

Disodium EDTA

PEG-8

Hexylene Glycol

Citric Acid

Sodium Citrate

Tocopheryl Acetate

BHT

Magnesium Ascorbyl Phosphate

Sodium Benzoate

Potassium Sorbate

CI 14700

CI 19140

Water, Dimethicone, Butylene Glycol, Glycerin, Trisiloxane, Trehalose, Saccharomyces Lysate Extract, Sodium Hyaluronate, Aloe Barbadensis Leaf Extract, Aloe Barbadensis Leaf Water, Silybum Marianum Extract, Camellia Sinensis Leaf Extract, Aloe Barbadensis Leaf Polysaccharides, Sorbitol, Sodium Polyaspartate, Caffeine, Thermus Thermophillus Ferment, Lactobacillus Ferment Lysate, Palmitoyl Hexapeptide-12, Caprylyl Glycol, Sucrose, Hydroxyethyl Urea, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Oleth-10, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Saccharide Isomerate, Hydrogenated Lecithin, Tromethamine, Glyceryl Polymethacrylate, Disodium EDTA, PEG-8, Hexylene Glycol, Citric Acid, Sodium Citrate, Tocopheryl Acetate, BHT, Magnesium Ascorbyl Phosphate, Phenoxyethanol, Sodium Benzoate, Potassium Sorbate, CI 14700, CI 19140

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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