Educational guide
Biossance Squalane + Omega Repair Cream Versus Clarins Extra-Firming Wrinkle Control Regenerating Night Cream
Biossance Squalane + Omega Repair Cream Versus Clarins Extra-Firming Wrinkle Control Regenerating Night Cream This barrier-repair moisturizer is formulated around Squalane and Ceramide NP to strengthen the skin barrier and hydrate skin. This night moisturizer
This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.
Biossance Squalane + Omega Repair Cream Versus Clarins Extra-Firming Wrinkle Control Regenerating Night Cream
This barrier-repair moisturizer is formulated around Squalane and Ceramide NP to strengthen the skin barrier and hydrate skin.
This night moisturizer is formulated around Butyrospermum Parkii Butter to hydrate skin.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Squalane
Glycerin
Caprylic/Capric Triglyceride
Isoamyl Laurate
Butyrospermum Parkii Butter
Sorbitan Olivate
Cetearyl Olivate
Ceramide NP
Jojoba Esters
Sodium Hyaluronate
Euterpe Oleracea Sterols
Linoleic Acid
Oleic Acid
Linolenic Acid
Ethyl Linoleate
Tocopherol
Isoamyl Cocoate
Cetyl Palmitate
Sorbitan Palmitate
Cetearyl Alcohol
Ethylhexylglycerin
Carbomer
Sodium Hydroxide
Phenoxyethanol
Sodium Gluconate
Water, Squalane, Glycerin, Caprylic/Capric Triglyceride, Isoamyl Laurate, Butyrospermum Parkii Butter, Sorbitan Olivate, Cetearyl Olivate, Ceramide NP, Jojoba Esters, Sodium Hyaluronate, Euterpe Oleracea Sterols, Linoleic Acid, Oleic Acid, Linolenic Acid, Ethyl Linoleate, Tocopherol, Isoamyl Cocoate, Cetyl Palmitate, Sorbitan Palmitate, Cetearyl Alcohol, Ethylhexylglycerin, Carbomer, Sodium Hydroxide, Phenoxyethanol, Sodium Gluconate
Cetearyl Isononanoate
Dicaprylyl Carbonate
Hydrogenated Coco-Glycerides
1,2-Hexanediol
Glyceryl Stearate
PEG-100 Stearate
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Cetearyl Glucoside
Glyceryl Caprylate
Parfum
Anigozanthos Flavidus Extract
Disodium EDTA
Tocopheryl Acetate
Butylene Glycol
Betaine
Sorbitol
Tromethamine
Marrubium Vulgare Extract
Kalanchoe Pinnata Leaf Extract
Balanites Roxburghii Seed Oil
Mitracarpus Scaber Extract
Sodium Benzoate
Citric Acid
Hydrated Silica
Phenethyl Alcohol
Furcellaria Lumbricalis Extract
Potassium Sorbate
Lapsana Communis Flower/Leaf/Stem Extract
Maris Sal
Water, Caprylic/Capric Triglyceride, Cetearyl Isononanoate, Glycerin, Dicaprylyl Carbonate, Cetearyl Alcohol, Hydrogenated Coco-Glycerides, 1,2-Hexanediol, Butyrospermum Parkii Butter, Glyceryl Stearate, PEG-100 Stearate, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Cetearyl Glucoside, Glyceryl Caprylate, Parfum, Anigozanthos Flavidus Extract, Disodium EDTA, Ethylhexylglycerin, Tocopheryl Acetate, Butylene Glycol, Betaine, Sorbitol, Tromethamine, Marrubium Vulgare Extract, Kalanchoe Pinnata Leaf Extract, Balanites Roxburghii Seed Oil, Mitracarpus Scaber Extract, Sodium Benzoate, Citric Acid, Hydrated Silica, Phenethyl Alcohol, Furcellaria Lumbricalis Extract, Potassium Sorbate, Lapsana Communis Flower/Leaf/Stem Extract, Maris Sal
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
This ingredient is also known as shea butter. It is a plant-derived extract from the nuts of the Africa shea tree and one of the most well-studied emollients.
Because it has a high concentration of fatty acids (primarily oleic, stearic, and linoleic) it is able to form a protective barrier on the skin's surface. This helps seal in moisture and prevents transepidermal water loss (TEWL).
In vitro research found an increase in skin hydration by 58% and a decrease in TEWL by 37.8% after 24 hours of applying this ingredient (pretty impressive for a single ingredient!).
Besides hydration, shea butter also contains triterpenes that have anti-inflammatory potential. In particule, lupeol cinnamate has shown the highest anti-inflammatory activity in vivo.
Shea butter also contains vitamins A and E which may contribute to antioxidant activity.
While Shea Butter has an SPF rating of about 3-4, it is not a sunscreen replacement.
This ingredient may not be fungal acne safe because its fatty acids fall within the C11-C24 range that the Malassezia yeast can metabolize.
Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.
Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.
In practice, that translates to a long shelf life and a consistently elegant skin feel.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.
Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.
This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.
This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.
Cetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier.
Despite having "alcohol" in its name, it has nothing to do with drying solvent alcohols; the FDA also allows "alcohol-free" products to contain fatty alcohols like this ingredient.
It plays several roles in a formula:
Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products.
Multiple assessments have found it to be non-irritating and non-sensitizing to most people.
However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers.
Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy.
Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans.
Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients.
This ingredient is not fungal acne safe. Cetearyl alcohol is a fatty alcohol with chain lengths that fall within the range that Malassezia can metabolize.
A 2019 study has also observed Malassezia growth in the presence of this ingredient, confirming it to be not-fungal acne safe.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!