Independent education resourceInformation here does not replace care from a qualified health professional.
Peptide Therapy GuideClear peptide education

Educational guide

Biossance Squalane + Marine Algae Eye Cream Versus SkinCeuticals A.G.E. Advanced Eye

Biossance Squalane + Marine Algae Eye Cream Versus SkinCeuticals A.G.E. Advanced Eye This anti-aging eye moisturizer is formulated around Squalane and Palmitoyl Tripeptide-5 to soften the look of wrinkles and hydrate skin. This anti-aging eye moisturizer is fo

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

Biossance Squalane + Marine Algae Eye Cream Versus SkinCeuticals A.G.E. Advanced Eye

This anti-aging eye moisturizer is formulated around Squalane and Palmitoyl Tripeptide-5 to soften the look of wrinkles and hydrate skin.

This anti-aging eye moisturizer is formulated around Caffeine and Palmitoyl Tripeptide-1 to soften the look of wrinkles and refine skin texture.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Caprylic/Capric Triglyceride

Squalane

Glycerin

Sorbitan Olivate

Cetearyl Olivate

Jojoba Esters

Glyceryl Stearate Se

Panthenol

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Cetyl Palmitate

Spilanthes Acmella Flower Extract

Palmitoyl Tripeptide-5

Sorbitan Palmitate

Dunaliella Salina Extract

Astaxanthin

Sodium Hyaluronate

Phenoxyethanol

Ethylhexylglycerin

Tocopherol

Citric Acid

Water, Caprylic/Capric Triglyceride, Squalane, Glycerin, Sorbitan Olivate, Cetearyl Olivate, Jojoba Esters, Glyceryl Stearate Se, Panthenol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Cetyl Palmitate, Spilanthes Acmella Flower Extract, Palmitoyl Tripeptide-5, Sorbitan Palmitate, Dunaliella Salina Extract, Astaxanthin, Sodium Hyaluronate, Phenoxyethanol, Ethylhexylglycerin, Tocopherol, Citric Acid

Hexyl Laurate

Cellulose

Polyethylene

Octyldodecanol

Butylene Glycol

Caffeine

Silica Silylate

Tocopheryl Acetate

Ammonium Polyacryloyldimethyl Taurate

Sodium Citrate

Dimethicone/Polyglycerin-3 Crosspolymer

Chlorphenesin

Boron Nitride

Alumina

Glycyrrhetinic Acid

CI 77891

Menthoxypropanediol

Sorbitol

Vaccinium Myrtillus Fruit Extract

Synthetic Fluorphlogopite

Sodium Phytate

Carbomer

Sodium Lactate

Polysorbate 20

Punica Granatum Fruit Extract

Glycol

Alcohol

Palmitoyl Tripeptide-1

Palmitoyl Tetrapeptide-7

Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate

Hexyl Laurate, Cellulose, Polyethylene, Caprylic/Capric Triglyceride, Octyldodecanol, Phenoxyethanol, Butylene Glycol, Caffeine, Silica Silylate, Tocopheryl Acetate, Ammonium Polyacryloyldimethyl Taurate, Sodium Citrate, Dimethicone/Polyglycerin-3 Crosspolymer, Chlorphenesin, Boron Nitride, Alumina, Glycyrrhetinic Acid, CI 77891, Menthoxypropanediol, Sorbitol, Vaccinium Myrtillus Fruit Extract, Synthetic Fluorphlogopite, Sodium Phytate, Carbomer, Sodium Lactate, Polysorbate 20, Punica Granatum Fruit Extract, Glycol, Alcohol, Palmitoyl Tripeptide-1, Tocopherol, Palmitoyl Tetrapeptide-7, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate

Reviews

Be the first to review

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.

Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.

In practice, that translates to a long shelf life and a consistently elegant skin feel.

While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.

Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.

This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.

This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Tocopherol is a fat-soluble antioxidant known as Vitamin E.

You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.

Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.

It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.

This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.

Concentrations usually range from 0.1-1% in most leave-on products.

Similar Comparisons

Connected reading

Helpful context for this guide

Source-derived material selected through this article’s indexed topics.

P

About the author

Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

View all articles →