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Biossance Squalane + 10% Vitamin C Dark Spot Serum Versus Drunk Elephant C-Firma Fresh Day Serum

Biossance Squalane + 10% Vitamin C Dark Spot Serum Versus Drunk Elephant C-Firma Fresh Day Serum This brightening serum is formulated around 3-O-Ethyl Ascorbic Acid and Squalane to fade the look of dark spots and brighten dull-looking skin. This brightening se

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

Biossance Squalane + 10% Vitamin C Dark Spot Serum Versus Drunk Elephant C-Firma Fresh Day Serum

This brightening serum is formulated around 3-O-Ethyl Ascorbic Acid and Squalane to fade the look of dark spots and brighten dull-looking skin.

This brightening serum is formulated around Ascorbic Acid and Tocopherol to brighten dull-looking skin and soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

No concerns

Ingredients Side-by-side

Water

Glycerin

3-O-Ethyl Ascorbic Acid

Squalane

Lentinus Edodes Mycelium Extract

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Glycyrrhiza Glabra Root Extract

Sodium Hyaluronate

Citric Acid

Polyacrylate Crosspolymer-6

Acacia Senegal Gum

Xanthan Gum

Sodium Gluconate

Sodium Citrate

Phenoxyethanol

Ethylhexylglycerin

Water, Glycerin, 3-O-Ethyl Ascorbic Acid, Squalane, Lentinus Edodes Mycelium Extract, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Glycyrrhiza Glabra Root Extract, Sodium Hyaluronate, Citric Acid, Polyacrylate Crosspolymer-6, Acacia Senegal Gum, Xanthan Gum, Sodium Gluconate, Sodium Citrate, Phenoxyethanol, Ethylhexylglycerin

Dimethyl Isosorbide

Ascorbic Acid

Laureth-23

Tocopherol

Lactobacillus/Pumpkin Ferment Extract

Sclerocarya Birrea Seed Oil

Dipotassium Glycyrrhizate

Vitis Vinifera Juice Extract

Ferulic Acid

Phyllanthus Emblica Fruit Extract

Camellia Sinensis Leaf Extract

Lactobacillus/Punica Granatum Fruit Ferment Extract

Propanediol

Gluconolactone

Sodium Hyaluronate Crosspolymer

Oryza Sativa Bran Extract

Glutamylamidoethyl Imidazole

Tetrahydrobisdemethoxydiferuloylmethane

Tetrahydrodemethoxydiferuloylmethane

Tetrahydrodiferuloylmethane

Pentylene Glycol

Caprylhydroxamic Acid

Leuconostoc/Radish Root Ferment Filtrate

Sorbic Acid

Sodium Benzoate

Caprylyl Glycol

Chondrus Crispus Extract

Water, Dimethyl Isosorbide, Ascorbic Acid, Laureth-23, Glycerin, Tocopherol, Lactobacillus/Pumpkin Ferment Extract, Sclerocarya Birrea Seed Oil, Dipotassium Glycyrrhizate, Glycyrrhiza Glabra Root Extract, Vitis Vinifera Juice Extract, Ferulic Acid, Phyllanthus Emblica Fruit Extract, Camellia Sinensis Leaf Extract, Lactobacillus/Punica Granatum Fruit Ferment Extract, Propanediol, Gluconolactone, Sodium Hyaluronate Crosspolymer, Sodium Hyaluronate, Oryza Sativa Bran Extract, Glutamylamidoethyl Imidazole, Tetrahydrobisdemethoxydiferuloylmethane, Tetrahydrodemethoxydiferuloylmethane, Tetrahydrodiferuloylmethane, Pentylene Glycol, Caprylhydroxamic Acid, Leuconostoc/Radish Root Ferment Filtrate, Sorbic Acid, Phenoxyethanol, Sodium Benzoate, Caprylyl Glycol, Chondrus Crispus Extract, Ethylhexylglycerin

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Glycyrrhiza Glabra Root Extract is an extract of the roots of Licorice. It has been found to have several benefits such as skin hydrating, conditioning, and soothing.

One component, glabridin, has extra potent antioxidant and soothing properties. It has also been found to block pigmentation from UVB rays in guinea pigs.

Licorice Root also contains a flavonoid. Flavonoids are a natural substance from in plants. Flavonoids also have antioxidant properties.

Another component, glycyrrhizin, has been found to have anti-inflammatory and antimicrobial benefits. This may make licorice root extract effective at treating acne. However, more research is needed to support this.

Liquiritin is one of the flavone compounds found in licorice. It has been found to help lighten skin by preventing tyrosinase from reacting with tyrosine. When the two react, protein is converted to melanin. Melanin is the substance in your body that gives your features pigmentation.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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About the author

Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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