Educational guide
Biologique Recherche Lotion P50W Versus SkinBetter Science AlphaRet Clearing Serum
Biologique Recherche Lotion P50W Versus SkinBetter Science AlphaRet Clearing Serum This smoothing toner is formulated around Gluconolactone and Niacinamide to refine skin texture and refine the look of pores. This acne serum is formulated around Lactic Acid an
This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.
Biologique Recherche Lotion P50W Versus SkinBetter Science AlphaRet Clearing Serum
This smoothing toner is formulated around Gluconolactone and Niacinamide to refine skin texture and refine the look of pores.
This acne serum is formulated around Lactic Acid and Ethyl Lactyl Retinoate to clear breakouts and refine skin texture.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Gluconolactone
Niacinamide
Glycerin
Propylene Glycol
Lactic Acid
Ethoxydiglycol
Magnesium Chloride
Malic Acid
Arctium Lappa Root Extract
Cochlearia Armoracia Root Extract
Quillaja Saponaria Bark Extract
Arnica Montana Flower Extract
Capsicum Frutescens Fruit Extract
Phytic Acid
Citric Acid
Sodium Lactate
Allantoin
Serine
Sulfur
Vinegar
Sodium Salicylate
Sorbitol
Tea-Lactate
Urea
Sodium Benzoate
Sodium Bisulfite
Water, Gluconolactone, Niacinamide, Glycerin, Propylene Glycol, Lactic Acid, Ethoxydiglycol, Magnesium Chloride, Malic Acid, Arctium Lappa Root Extract, Cochlearia Armoracia Root Extract, Quillaja Saponaria Bark Extract, Arnica Montana Flower Extract, Capsicum Frutescens Fruit Extract, Phytic Acid, Citric Acid, Sodium Lactate, Allantoin, Serine, Sulfur, Vinegar, Sodium Salicylate, Sorbitol, Tea-Lactate, Urea, Sodium Benzoate, Sodium Bisulfite
Pentylene Glycol
Ethylhexyl Olivate
Sorbitan Stearate
Neopentyl Glycol Diethylhexanoate
PPG-3 Isostearyl Methyl Ether
Dimethyl Isosorbide
Glyceryl Stearate
PEG-100 Stearate
Magnesium Aluminum Silicate
Zinc PCA
Steareth-2
Ethyl Lactyl Retinoate
Salicylic Acid
Oligopeptide-10
Sodium Hyaluronate
Decylene Glycol
Artemisia Vulgaris Extract
Bisabolol
Tocopheryl Acetate
Camellia Sinensis Leaf Extract
Laminaria Digitata Extract
Tasmannia Lanceolata Fruit/Leaf Extract
Boswellia Serrata Extract
Zingiber Officinale Root Extract
Honey Extract
Oryza Sativa Bran Extract
Cetearyl Alcohol
Butylene Glycol
Xanthan Gum
Lecithin
Sclerotium Gum
Disodium EDTA
Pullulan
Ethylhexylglycerin
Silica
Phenoxyethanol
Water, Lactic Acid, Sodium Lactate, Pentylene Glycol, Ethylhexyl Olivate, Sorbitan Stearate, Neopentyl Glycol Diethylhexanoate, PPG-3 Isostearyl Methyl Ether, Glycerin, Dimethyl Isosorbide, Glyceryl Stearate, PEG-100 Stearate, Magnesium Aluminum Silicate, Niacinamide, Zinc PCA, Steareth-2, Ethyl Lactyl Retinoate, Salicylic Acid, Oligopeptide-10, Sodium Hyaluronate, Decylene Glycol, Artemisia Vulgaris Extract, Bisabolol, Tocopheryl Acetate, Camellia Sinensis Leaf Extract, Laminaria Digitata Extract, Tasmannia Lanceolata Fruit/Leaf Extract, Boswellia Serrata Extract, Zingiber Officinale Root Extract, Honey Extract, Oryza Sativa Bran Extract, Cetearyl Alcohol, Butylene Glycol, Xanthan Gum, Lecithin, Sclerotium Gum, Disodium EDTA, Pullulan, Ethylhexylglycerin, Silica, Phenoxyethanol, Sodium Benzoate
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Lactic Acid is another well-loved alpha hydroxy acid (AHA). It is gentler than glycolic acid but still highly effective.
Its main role is to exfoliate the surface of the skin by loosening the “glue” that holds dead skin cells together. Shedding those old cells leads to smoother, softer, and more even-toned skin.
Because lactic acid molecules are larger than glycolic acid, they don’t penetrate as deeply. This means they’re less likely to sting or irritate, making it a great choice for beginners or those with sensitive skin.
Like glycolic acid, it can:
Lactic acid also acts as a humectant (like hyaluronic acid). It can draw water into the skin to improve hydration and also plays a role in the skin's natural moisturizing factor (NMF) in the form of sodium lactate.
Studies show it can boost ceramide production to strengthen the skin barrier and even help balance the skin’s microbiome.
To get results, choose products with a pH between 3-4.
Lower strengths (5-12%) focus on surface exfoliation; higher strengths (12% and up) can reach deeper in the dermis (deeper, supportive layer) to improve skin texture and firmness over time.
Though it was originally derived from milk, most modern lactic acid used in skincare is vegan. It is made through non-dairy fermentation to create a bio-identical and stable form suitable for all formulations.
When lactic acid shows up near the end of an ingredient list, it usually means the brand added just a tiny amount to adjust the product’s pH.
Legend has it that Cleopatra used to bathe in sour milk to help reduce wrinkles.
Lactic acid is truly a gentle multitasker: it exfoliates, hydrates, strengthens, and brightens. It's a great ingredient for giving your skin a smooth, glowing, and healthy look without the harshness of stronger acids.
Read more about some other popular AHA's here:
Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.
Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.
Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.
It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.
Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.
We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.
Sodium Lactate is the sodium salt of lactic acid, an AHA. It is a humectant and sometimes used to adjust the pH of a product.
This ingredient is part of our skin's NMF, or natural moisturizing factor. Our NMF is essential for the hydration of our top skin layers and plasticity of skin. NMF also influences our skin's natural acid mantle and pH, which protects our skin from harmful bacteria.
High percentages of Sodium Lactate can have an exfoliating effect.
Fun fact: Sodium Lactate is produced from fermented sugar.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!