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Biologique Recherche Crème VG Derm Nourishing and Moisturizing Face Cream Versus SkinCeuticals Triple Lipid Restore 2:4:2

Biologique Recherche Crème VG Derm Nourishing and Moisturizing Face Cream Versus SkinCeuticals Triple Lipid Restore 2:4:2 This barrier-repair moisturizer is formulated around Macadamia Ternifolia Seed Oil and Niacinamide to strengthen the skin barrier and hydr

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

Biologique Recherche Crème VG Derm Nourishing and Moisturizing Face Cream Versus SkinCeuticals Triple Lipid Restore 2:4:2

This barrier-repair moisturizer is formulated around Macadamia Ternifolia Seed Oil and Niacinamide to strengthen the skin barrier and hydrate skin.

This barrier-repair moisturizer is formulated around Cholesterol and Ceramide NP to strengthen the skin barrier and soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Propylene Glycol

Glycerin

Caprylic/Capric Triglyceride

Cetyl Alcohol

Macadamia Ternifolia Seed Oil

Sucrose Polystearate

Jojoba Esters

Gossypium Herbaceum Seed Oil

Niacinamide

Hippophae Rhamnoides Oil

Helianthus Annuus Seed Wax

Betula Alba Bark Extract

Equisetum Arvense Extract

Hedera Helix Leaf/Stem Extract

Fucus Vesiculosus Extract

Centella Asiatica Extract

Helianthus Annuus Seed Oil

Rosmarinus Officinalis Leaf Extract

Yeast Extract

Rhizobian Gum

Lactic Acid

Sodium Lactate

Allantoin

Serine

Sodium Hyaluronate

Acacia Decurrens Flower Wax

Sorbitol

Tocopherol

Sodium Stearoyl Glutamate

Hydrogenated Polyisobutene

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Tea-Lactate

Polyglyceryl-3 PCA

Urea

Phenoxyethanol

Ethylhexylglycerin

Sodium Benzoate

Chlorphenesin

Water, Propylene Glycol, Glycerin, Caprylic/Capric Triglyceride, Cetyl Alcohol, Macadamia Ternifolia Seed Oil, Sucrose Polystearate, Jojoba Esters, Gossypium Herbaceum Seed Oil, Niacinamide, Hippophae Rhamnoides Oil, Helianthus Annuus Seed Wax, Betula Alba Bark Extract, Equisetum Arvense Extract, Hedera Helix Leaf/Stem Extract, Fucus Vesiculosus Extract, Centella Asiatica Extract, Helianthus Annuus Seed Oil, Rosmarinus Officinalis Leaf Extract, Yeast Extract, Rhizobian Gum, Lactic Acid, Sodium Lactate, Allantoin, Serine, Sodium Hyaluronate, Acacia Decurrens Flower Wax, Sorbitol, Tocopherol, Sodium Stearoyl Glutamate, Hydrogenated Polyisobutene, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Tea-Lactate, Polyglyceryl-3 PCA, Urea, Phenoxyethanol, Ethylhexylglycerin, Sodium Benzoate, Chlorphenesin

Dimethicone

Cholesterol

C12-15 Alkyl Benzoate

Ceramide NP

Helianthus Annuus Seed Oil Unsaponifiables

Bis-PEG-18 Methyl Ether Dimethyl Silane

Sodium Polyacrylate

PEG-10 Dimethicone

Nylon-12

Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone

Dimethicone/PEG-10/15 Crosspolymer

Disteardimonium Hectorite

Hydroxyethylpiperazine Ethane Sulfonic Acid

Ammonium Polyacryloyldimethyl Taurate

Caprylyl Glycol

PEG/PPG-18/18 Dimethicone

Propylene Carbonate

Disodium EDTA

Acrylonitrile/Methyl Methacrylate/Vinylidene Chloride Copolymer

Adenosine

Dipropylene Glycol

Lavandula Angustifolia Oil

Rosmarinus Officinalis Leaf Oil

T-Butyl Alcohol

Mentha Piperita Oil

Sodium Citrate

Linalool

Isobutane

Ceramide EOP

BHT

Limonene

Water, Dimethicone, Hydrogenated Polyisobutene, Glycerin, Cholesterol, C12-15 Alkyl Benzoate, Ceramide NP, Helianthus Annuus Seed Oil Unsaponifiables, Bis-PEG-18 Methyl Ether Dimethyl Silane, Sodium Polyacrylate, PEG-10 Dimethicone, Nylon-12, Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone, Dimethicone/PEG-10/15 Crosspolymer, Phenoxyethanol, Disteardimonium Hectorite, Hydroxyethylpiperazine Ethane Sulfonic Acid, Ammonium Polyacryloyldimethyl Taurate, Chlorphenesin, Caprylyl Glycol, PEG/PPG-18/18 Dimethicone, Propylene Carbonate, Disodium EDTA, Acrylonitrile/Methyl Methacrylate/Vinylidene Chloride Copolymer, Adenosine, Dipropylene Glycol, Lavandula Angustifolia Oil, Rosmarinus Officinalis Leaf Oil, T-Butyl Alcohol, Mentha Piperita Oil, Sodium Citrate, Linalool, Isobutane, Ceramide EOP, BHT, Tocopherol, Limonene

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Chlorphenesin is a synthetic preservative. It helps protect a product against bacteria in order to extend shelf life. In most cases, Chlorphenesin is paired with other preservatives such as phenoxyethanol and caprylyl glycol.

Chlorphenesin is a biocide. This means it is able to help fight the microorganisms on our skin. It is also able to fight odor-releasing bacteria.

Chlorphenesin is soluble in both water and glycerin.

Studies show Chlorphenesin is easily absorbed by our skin. You should speak with a skincare professional if you have concerns about using Chlorphenesin.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Hydrogenated Polyisobutene is a synthetic polymer. Polymers are compounds with high molecular weight. Hydrogenated Polyisobutene is an emollient and texture enhancer.

In one study, Hydrogenated Polyisobutene showed better skin hydration levels than Caprylic/Capric Triglyceride. As an emollient, it helps keep your skin soft and hydrated by trapping moisture in.

Hydrogenated Polyisobutene is often used as a mineral oil replacement.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Tocopherol is a fat-soluble antioxidant known as Vitamin E.

You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.

Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.

It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.

This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.

Concentrations usually range from 0.1-1% in most leave-on products.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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