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Biologique Recherche Crème Iso-Placenta Regenerating Face Cream Versus Medik8 Total Moisture Daily Facial Cream

Biologique Recherche Crème Iso-Placenta Regenerating Face Cream Versus Medik8 Total Moisture Daily Facial Cream This smoothing moisturizer is formulated around Niacinamide and Centella Asiatica Extract to refine skin texture and fade the look of dark spots. Th

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

Biologique Recherche Crème Iso-Placenta Regenerating Face Cream Versus Medik8 Total Moisture Daily Facial Cream

This smoothing moisturizer is formulated around Niacinamide and Centella Asiatica Extract to refine skin texture and fade the look of dark spots.

This barrier-repair moisturizer is formulated around Squalane and Saccharomyces Ferment Filtrate to strengthen the skin barrier and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Propylene Glycol

Dicaprylyl Carbonate

Glycerin

Sucrose Polystearate

C10-18 Triglycerides

Cetyl Alcohol

1,2-Hexanediol

Niacinamide

Passiflora Edulis Seed Oil

Polyamide-5

Betula Alba Bark Extract

Equisetum Arvense Extract

Hedera Helix Leaf/Stem Extract

Fucus Vesiculosus Extract

Centella Asiatica Extract

Glycine Soja Oil

Yeast Extract

Bacillus/Soybean Ferment Extract

Hexapeptide-11

Oligopeptide-1

Oligopeptide-2

Oligopeptide-3

Ascorbyl Glucoside

Acetyl Glutamine

Folic Acid

Sodium Hyaluronate

Lecithin

Tocopherol

Sodium Stearoyl Glutamate

Butylene Glycol

Hydrogenated Polyisobutene

Polyacrylate Crosspolymer-6

T-Butyl Alcohol

Caprylyl Glycol

Water, Propylene Glycol, Dicaprylyl Carbonate, Glycerin, Sucrose Polystearate, C10-18 Triglycerides, Cetyl Alcohol, 1,2-Hexanediol, Niacinamide, Passiflora Edulis Seed Oil, Polyamide-5, Betula Alba Bark Extract, Equisetum Arvense Extract, Hedera Helix Leaf/Stem Extract, Fucus Vesiculosus Extract, Centella Asiatica Extract, Glycine Soja Oil, Yeast Extract, Bacillus/Soybean Ferment Extract, Hexapeptide-11, Oligopeptide-1, Oligopeptide-2, Oligopeptide-3, Ascorbyl Glucoside, Acetyl Glutamine, Folic Acid, Sodium Hyaluronate, Lecithin, Tocopherol, Sodium Stearoyl Glutamate, Butylene Glycol, Hydrogenated Polyisobutene, Polyacrylate Crosspolymer-6, T-Butyl Alcohol, Caprylyl Glycol

Dimethicone

Squalane

Caprylic/Capric Triglyceride

Bis-PEG-18 Methyl Ether Dimethyl Silane

Pentaerythrityl Tetraethylhexanoate

Propanediol

Arachidyl Alcohol

Cetearyl Alcohol

Inulin

Behenyl Alcohol

Phenoxyethanol

Arachidyl Glucoside

Tocopheryl Acetate

Linoleic Acid

Saccharomyces Ferment Filtrate

Glyceryl Glucoside

Acetyl Heptapeptide-4

Linolenic Acid

Cetearyl Glucoside

Sodium Polyacryloyldimethyl Taurate

Diglycerin

Ceramide NP

Sodium PCA

Urea

Carbomer

Disodium EDTA

Hydrogenated Polydecene

Ethylhexylglycerin

Xanthan Gum

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Sodium Hydroxide

Lactic Acid

Lysine

PCA

Sorbitol

Trideceth-10

Hydrolyzed Wheat Protein

Allantoin

Oryza Sativa Lees Extract

Water, Glycerin, Dimethicone, Squalane, Caprylic/Capric Triglyceride, Bis-PEG-18 Methyl Ether Dimethyl Silane, Pentaerythrityl Tetraethylhexanoate, Propanediol, Arachidyl Alcohol, Cetearyl Alcohol, Inulin, Behenyl Alcohol, Phenoxyethanol, Arachidyl Glucoside, Tocopheryl Acetate, Caprylyl Glycol, Linoleic Acid, Saccharomyces Ferment Filtrate, Glyceryl Glucoside, Sodium Hyaluronate, Acetyl Heptapeptide-4, Linolenic Acid, Cetearyl Glucoside, Sodium Polyacryloyldimethyl Taurate, Diglycerin, Ceramide NP, Sodium PCA, Urea, Carbomer, Disodium EDTA, Hydrogenated Polydecene, Ethylhexylglycerin, Xanthan Gum, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Sodium Hydroxide, Lactic Acid, Lysine, PCA, Sorbitol, Butylene Glycol, 1,2-Hexanediol, Trideceth-10, Tocopherol, Hydrolyzed Wheat Protein, Allantoin, Oryza Sativa Lees Extract

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Tocopherol is a fat-soluble antioxidant known as Vitamin E.

You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.

Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.

It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.

This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.

Concentrations usually range from 0.1-1% in most leave-on products.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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