Educational guide
Biologique Recherche Crème Iso-Placenta Regenerating Face Cream Versus Biologique Recherche Lotion P50W
Biologique Recherche Crème Iso-Placenta Regenerating Face Cream Versus Biologique Recherche Lotion P50W This smoothing moisturizer is formulated around Niacinamide and Centella Asiatica Extract to refine skin texture and fade the look of dark spots. This smoot
This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.
Biologique Recherche Crème Iso-Placenta Regenerating Face Cream Versus Biologique Recherche Lotion P50W
This smoothing moisturizer is formulated around Niacinamide and Centella Asiatica Extract to refine skin texture and fade the look of dark spots.
This smoothing toner is formulated around Gluconolactone and Niacinamide to refine skin texture and refine the look of pores.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Propylene Glycol
Dicaprylyl Carbonate
Glycerin
Sucrose Polystearate
C10-18 Triglycerides
Cetyl Alcohol
1,2-Hexanediol
Niacinamide
Passiflora Edulis Seed Oil
Polyamide-5
Betula Alba Bark Extract
Equisetum Arvense Extract
Hedera Helix Leaf/Stem Extract
Fucus Vesiculosus Extract
Centella Asiatica Extract
Glycine Soja Oil
Yeast Extract
Bacillus/Soybean Ferment Extract
Hexapeptide-11
Oligopeptide-1
Oligopeptide-2
Oligopeptide-3
Ascorbyl Glucoside
Acetyl Glutamine
Folic Acid
Sodium Hyaluronate
Lecithin
Tocopherol
Sodium Stearoyl Glutamate
Butylene Glycol
Hydrogenated Polyisobutene
Polyacrylate Crosspolymer-6
T-Butyl Alcohol
Caprylyl Glycol
Water, Propylene Glycol, Dicaprylyl Carbonate, Glycerin, Sucrose Polystearate, C10-18 Triglycerides, Cetyl Alcohol, 1,2-Hexanediol, Niacinamide, Passiflora Edulis Seed Oil, Polyamide-5, Betula Alba Bark Extract, Equisetum Arvense Extract, Hedera Helix Leaf/Stem Extract, Fucus Vesiculosus Extract, Centella Asiatica Extract, Glycine Soja Oil, Yeast Extract, Bacillus/Soybean Ferment Extract, Hexapeptide-11, Oligopeptide-1, Oligopeptide-2, Oligopeptide-3, Ascorbyl Glucoside, Acetyl Glutamine, Folic Acid, Sodium Hyaluronate, Lecithin, Tocopherol, Sodium Stearoyl Glutamate, Butylene Glycol, Hydrogenated Polyisobutene, Polyacrylate Crosspolymer-6, T-Butyl Alcohol, Caprylyl Glycol
Gluconolactone
Lactic Acid
Ethoxydiglycol
Magnesium Chloride
Malic Acid
Arctium Lappa Root Extract
Cochlearia Armoracia Root Extract
Quillaja Saponaria Bark Extract
Arnica Montana Flower Extract
Capsicum Frutescens Fruit Extract
Phytic Acid
Citric Acid
Sodium Lactate
Allantoin
Serine
Sulfur
Vinegar
Sodium Salicylate
Sorbitol
Tea-Lactate
Urea
Sodium Benzoate
Sodium Bisulfite
Water, Gluconolactone, Niacinamide, Glycerin, Propylene Glycol, Lactic Acid, Ethoxydiglycol, Magnesium Chloride, Malic Acid, Arctium Lappa Root Extract, Cochlearia Armoracia Root Extract, Quillaja Saponaria Bark Extract, Arnica Montana Flower Extract, Capsicum Frutescens Fruit Extract, Phytic Acid, Citric Acid, Sodium Lactate, Allantoin, Serine, Sulfur, Vinegar, Sodium Salicylate, Sorbitol, Tea-Lactate, Urea, Sodium Benzoate, Sodium Bisulfite
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Propylene Glycol is a synthetic, colorless, odorless liquid that has been a staple in cosmetics for decades. It is a skin conditioning agent, humectant, and solvent.
As a humectant, it draw water to the skin to reduce flaking and restore suppleness. It's also a solvent that helps dissolve other actives and keeps formulas stable across temperature changes.
The CIR Expert Panel has confirmed this ingredient to be nontoxic and clinical studies show no sensitization at cosmetic use concentrations.
True allergic reactions are quite rare: a 15-year retrospective study of 6,751 patients found only 0.31% had a positive reaction (and less than half were considered clinically relevant).
It seemed that when sensitization does occur, it's most commonly linked to topical medication (like corticosteroids) and not cosmetics. Allergic contact dermatitis also appears largely limited to individuals with underlying skin conditions.
Overall, propylene glycol is a well-studied ingredient that most people can tolerate without issue.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!