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Biologique Recherche Crème Iso-Placenta Regenerating Face Cream Versus Alastin Restorative Skin Complex

Biologique Recherche Crème Iso-Placenta Regenerating Face Cream Versus Alastin Restorative Skin Complex This smoothing moisturizer is formulated around Niacinamide and Centella Asiatica Extract to refine skin texture and fade the look of dark spots. This anti-

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

Biologique Recherche Crème Iso-Placenta Regenerating Face Cream Versus Alastin Restorative Skin Complex

This smoothing moisturizer is formulated around Niacinamide and Centella Asiatica Extract to refine skin texture and fade the look of dark spots.

This anti-aging treatment is formulated around Niacinamide and Palmitoyl Hexapeptide-12 to soften the look of wrinkles and strengthen the skin barrier.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Propylene Glycol

Dicaprylyl Carbonate

Glycerin

Sucrose Polystearate

C10-18 Triglycerides

Cetyl Alcohol

1,2-Hexanediol

Niacinamide

Passiflora Edulis Seed Oil

Polyamide-5

Betula Alba Bark Extract

Equisetum Arvense Extract

Hedera Helix Leaf/Stem Extract

Fucus Vesiculosus Extract

Centella Asiatica Extract

Glycine Soja Oil

Yeast Extract

Bacillus/Soybean Ferment Extract

Hexapeptide-11

Oligopeptide-1

Oligopeptide-2

Oligopeptide-3

Ascorbyl Glucoside

Acetyl Glutamine

Folic Acid

Sodium Hyaluronate

Lecithin

Tocopherol

Sodium Stearoyl Glutamate

Butylene Glycol

Hydrogenated Polyisobutene

Polyacrylate Crosspolymer-6

T-Butyl Alcohol

Caprylyl Glycol

Water, Propylene Glycol, Dicaprylyl Carbonate, Glycerin, Sucrose Polystearate, C10-18 Triglycerides, Cetyl Alcohol, 1,2-Hexanediol, Niacinamide, Passiflora Edulis Seed Oil, Polyamide-5, Betula Alba Bark Extract, Equisetum Arvense Extract, Hedera Helix Leaf/Stem Extract, Fucus Vesiculosus Extract, Centella Asiatica Extract, Glycine Soja Oil, Yeast Extract, Bacillus/Soybean Ferment Extract, Hexapeptide-11, Oligopeptide-1, Oligopeptide-2, Oligopeptide-3, Ascorbyl Glucoside, Acetyl Glutamine, Folic Acid, Sodium Hyaluronate, Lecithin, Tocopherol, Sodium Stearoyl Glutamate, Butylene Glycol, Hydrogenated Polyisobutene, Polyacrylate Crosspolymer-6, T-Butyl Alcohol, Caprylyl Glycol

Isopropyl Palmitate

Polyacrylate-13

Palmitoyl Hexapeptide-12

Palmitoyl Tripeptide-1

Palmitoyl Tripeptide-5

Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine

Palmitoyl Dipeptide-5 Diaminohydroxybutyrate

Acetyl Hexapeptide-38

Octapeptide-45

Swertia Chirata Extract

Magnolol

Ornithine

Ceramide AP

Ceramide NP

Ergothioneine

Dunaliella Salina Extract

Phytosterols

Phospholipids

Glycolipids

Tremella Fuciformis Sporocarp Extract

Caprylic/Capric Triglyceride

Stearic Acid

Betaine

Squalane

Caprylyl Methicone

Disodium EDTA

Polysorbate 20

Glyceryl Caprylate

Pentylene Glycol

Oleic Acid

Palmitic Acid

Hexylene Glycol

Propanediol

Polyisobutene

Potassium Sorbate

Levulinic Acid

Sodium Hydroxide

Helianthus Annuus Seed Oil

P-Anisic Acid

Sorbitan Isostearate

Ethylhexylglycerin

Phenoxyethanol

Water, Glycerin, Niacinamide, Isopropyl Palmitate, Polyacrylate-13, Butylene Glycol, Palmitoyl Hexapeptide-12, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-5, Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Palmitoyl Dipeptide-5 Diaminohydroxybutyrate, Acetyl Hexapeptide-38, Octapeptide-45, Swertia Chirata Extract, Magnolol, Ornithine, Ceramide AP, Ceramide NP, Ergothioneine, Dunaliella Salina Extract, Phytosterols, Phospholipids, Glycolipids, Tremella Fuciformis Sporocarp Extract, Caprylic/Capric Triglyceride, Sodium Stearoyl Glutamate, Stearic Acid, Betaine, Squalane, Lecithin, Caprylyl Methicone, Disodium EDTA, Polysorbate 20, Tocopherol, Caprylyl Glycol, Glyceryl Caprylate, Pentylene Glycol, Oleic Acid, Palmitic Acid, Hexylene Glycol, Propanediol, Polyisobutene, Potassium Sorbate, Levulinic Acid, Sodium Hydroxide, Helianthus Annuus Seed Oil, P-Anisic Acid, Sorbitan Isostearate, Ethylhexylglycerin, Phenoxyethanol

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of phospholipids.

Thanks to its amphiphilic structure (water-loving head and oil-loving tail), it is a true multitasker:

It plays well with most ingredients and is typically used at 0.1-1%. However, concentrations up to 50% have been reported in moisturizers.

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Sodium Stearoyl Glutamate is an amino-acid based emulsifier. It is made by combining stearic acid with L-glutamic acid and neutralizing it to a sodium salt.

As an emulsifier, it works mainly as an oil-in-water one and helps keep the oil and water in your formulas blended. It also contributes to a smooth, non-greasy skin feel.

This ingredient is biodegradable and commonly available in natural/COSMOS-certified grades.

Tocopherol is a fat-soluble antioxidant known as Vitamin E.

You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.

Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.

It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.

This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.

Concentrations usually range from 0.1-1% in most leave-on products.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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