Educational guide
Biologique Recherche Crème Iso-Placenta Regenerating Face Cream Versus Aestura Atobarrier 365 Cream
Biologique Recherche Crème Iso-Placenta Regenerating Face Cream Versus Aestura Atobarrier 365 Cream This smoothing moisturizer is formulated around Niacinamide and Centella Asiatica Extract to refine skin texture and fade the look of dark spots. This barrier-r
This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.
Biologique Recherche Crème Iso-Placenta Regenerating Face Cream Versus Aestura Atobarrier 365 Cream
This smoothing moisturizer is formulated around Niacinamide and Centella Asiatica Extract to refine skin texture and fade the look of dark spots.
This barrier-repair moisturizer is formulated around Squalane and Hydroxypropyl Bispalmitamide Mea to strengthen the skin barrier and hydrate skin.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Propylene Glycol
Dicaprylyl Carbonate
Glycerin
Sucrose Polystearate
C10-18 Triglycerides
Cetyl Alcohol
1,2-Hexanediol
Niacinamide
Passiflora Edulis Seed Oil
Polyamide-5
Betula Alba Bark Extract
Equisetum Arvense Extract
Hedera Helix Leaf/Stem Extract
Fucus Vesiculosus Extract
Centella Asiatica Extract
Glycine Soja Oil
Yeast Extract
Bacillus/Soybean Ferment Extract
Hexapeptide-11
Oligopeptide-1
Oligopeptide-2
Oligopeptide-3
Ascorbyl Glucoside
Acetyl Glutamine
Folic Acid
Sodium Hyaluronate
Lecithin
Tocopherol
Sodium Stearoyl Glutamate
Butylene Glycol
Hydrogenated Polyisobutene
Polyacrylate Crosspolymer-6
T-Butyl Alcohol
Caprylyl Glycol
Water, Propylene Glycol, Dicaprylyl Carbonate, Glycerin, Sucrose Polystearate, C10-18 Triglycerides, Cetyl Alcohol, 1,2-Hexanediol, Niacinamide, Passiflora Edulis Seed Oil, Polyamide-5, Betula Alba Bark Extract, Equisetum Arvense Extract, Hedera Helix Leaf/Stem Extract, Fucus Vesiculosus Extract, Centella Asiatica Extract, Glycine Soja Oil, Yeast Extract, Bacillus/Soybean Ferment Extract, Hexapeptide-11, Oligopeptide-1, Oligopeptide-2, Oligopeptide-3, Ascorbyl Glucoside, Acetyl Glutamine, Folic Acid, Sodium Hyaluronate, Lecithin, Tocopherol, Sodium Stearoyl Glutamate, Butylene Glycol, Hydrogenated Polyisobutene, Polyacrylate Crosspolymer-6, T-Butyl Alcohol, Caprylyl Glycol
Butylene Glycol Dicaprylate/Dicaprate
Cetyl Ethylhexanoate
Squalane
Pentaerythrityl Tetraisostearate
Behenyl Alcohol
Dimethicone
Hydroxypropyl Bispalmitamide Mea
Stearic Acid
Betaine
Mannitol
C14-22 Alcohols
Palmitic Acid
Hydroxypropyl Bislauramide Mea
Arachidyl Alcohol
Cholesterol
Polyacrylate-13
C12-20 Alkyl Glucoside
Allantoin
Arachidyl Glucoside
Ceramide NP
Glyceryl Caprylate
Ethylhexylglycerin
Carbomer
Tromethamine
Dimethiconol
Polyglyceryl-10 Laurate
Hydrogenated Lecithin
Ethylhexyl Palmitate
Acrylates/Ammonium Methacrylate Copolymer
Sorbitan Isostearate
Silica
Phytosphingosine
Sphingolipids
Arachidic Acid
Oleic Acid
Water, Butylene Glycol, Glycerin, Butylene Glycol Dicaprylate/Dicaprate, Cetyl Ethylhexanoate, Squalane, Pentaerythrityl Tetraisostearate, Dicaprylyl Carbonate, Behenyl Alcohol, Dimethicone, Hydroxypropyl Bispalmitamide Mea, Stearic Acid, Betaine, Mannitol, C14-22 Alcohols, Palmitic Acid, Hydroxypropyl Bislauramide Mea, Arachidyl Alcohol, Cholesterol, Polyacrylate-13, C12-20 Alkyl Glucoside, Allantoin, Arachidyl Glucoside, Niacinamide, Ceramide NP, Glyceryl Caprylate, Ethylhexylglycerin, Hydrogenated Polyisobutene, Carbomer, Tromethamine, Dimethiconol, Polyglyceryl-10 Laurate, Hydrogenated Lecithin, Ethylhexyl Palmitate, Acrylates/Ammonium Methacrylate Copolymer, Sorbitan Isostearate, Silica, Phytosphingosine, Sphingolipids, Arachidic Acid, Tocopherol, Oleic Acid
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Dicaprylyl Carbonate comes from carbonic acid and caprylyl alcohol, a fatty alcohol. It is an emollient and gives skin a velvet feel. The sources of Dicaprylyl Carbonate may be synthetic or from animals.
As an emollient, Dicaprylyl Carbonate creates a film on the skin. This film traps moisture in, keeping your skin soft and hydrated.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Hydrogenated Polyisobutene is a synthetic polymer. Polymers are compounds with high molecular weight. Hydrogenated Polyisobutene is an emollient and texture enhancer.
In one study, Hydrogenated Polyisobutene showed better skin hydration levels than Caprylic/Capric Triglyceride. As an emollient, it helps keep your skin soft and hydrated by trapping moisture in.
Hydrogenated Polyisobutene is often used as a mineral oil replacement.
Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Tocopherol is a fat-soluble antioxidant known as Vitamin E.
You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.
Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.
It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.
This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.
Concentrations usually range from 0.1-1% in most leave-on products.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!