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Biologique Recherche Crème Grand Millésime Radiance Revitalizing Face Cream Versus Stratia Interface Cream

Biologique Recherche Crème Grand Millésime Radiance Revitalizing Face Cream Versus Stratia Interface Cream This brightening moisturizer is formulated around Niacinamide to brighten dull-looking skin and refine skin texture. This anti-aging moisturizer is formu

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

Biologique Recherche Crème Grand Millésime Radiance Revitalizing Face Cream Versus Stratia Interface Cream

This brightening moisturizer is formulated around Niacinamide to brighten dull-looking skin and refine skin texture.

This anti-aging moisturizer is formulated around Squalane and Panthenol to soften the look of wrinkles and strengthen the skin barrier.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Propylene Glycol

Amniotic Fluid

Glycerin

Stearic Acid

Polysorbate 40

Palmitic Acid

Cetyl Alcohol

Pentylene Glycol

PEG-2 Stearate

Tea-Stearate

Alcohol Denat.

Sodium Hyaluronate

Myrtus Communis Extract

Mimosa Tenuiflora Bark Extract

Allium Cepa Bulb Extract

Commiphora Myrrha Resin Extract

Hamamelis Virginiana Bark/Leaf/Twig Extract

Cucumis Sativus Fruit Extract

Hypericum Perforatum Flower/Leaf/Stem Extract

Yeast Extract

Hydrolyzed Silk

Allantoin

Urea

Serine

Rhizobian Gum

Tea-Lactate

Citric Acid

Sodium Lactate

Salicylic Acid

Sodium Benzoate

Magnesium Chloride

Niacinamide

Vinegar

Lactic Acid

Gluconolactone

Pyridoxine Hcl

Thiamine Hcl

Potassium Sorbate

Sorbitol

Caprylyl Glycol

Chlorphenesin

Phenoxyethanol

Sodium Dehydroacetate

Alcohol

Sorbic Acid

Water, Propylene Glycol, Amniotic Fluid, Glycerin, Stearic Acid, Polysorbate 40, Palmitic Acid, Cetyl Alcohol, Pentylene Glycol, PEG-2 Stearate, Tea-Stearate, Alcohol Denat., Sodium Hyaluronate, Myrtus Communis Extract, Mimosa Tenuiflora Bark Extract, Allium Cepa Bulb Extract, Commiphora Myrrha Resin Extract, Hamamelis Virginiana Bark/Leaf/Twig Extract, Cucumis Sativus Fruit Extract, Hypericum Perforatum Flower/Leaf/Stem Extract, Yeast Extract, Hydrolyzed Silk, Allantoin, Urea, Serine, Rhizobian Gum, Tea-Lactate, Citric Acid, Sodium Lactate, Salicylic Acid, Sodium Benzoate, Magnesium Chloride, Niacinamide, Vinegar, Lactic Acid, Gluconolactone, Pyridoxine Hcl, Thiamine Hcl, Potassium Sorbate, Sorbitol, Caprylyl Glycol, Chlorphenesin, Phenoxyethanol, Sodium Dehydroacetate, Alcohol, Sorbic Acid

Squalane

Hydrogenated Polydecene

Panthenol

Ethoxydiglycol

Dimethicone

Rosa Canina Fruit Oil

Cetearyl Alcohol

Acetyl Glutamine

Sh-Oligopeptide-1

Sh-Oligopeptide-2

Sh-Polypeptide-1

Sh-Polypeptide-9

Sh-Polypeptide-11

Copper Palmitoyl Heptapeptide-14

Heptapeptide-15 Palmitate

Glycyrrhiza Glabra Root Extract

Butylene Glycol

Glycolic Acid

Lactic Acid/Glycolic Acid Copolymer

Disodium EDTA

Polyacrylamide

C13-14 Isoparaffin

Polyvinyl Alcohol

Methylparaben

Propylparaben

Laureth-7

Diazolidinyl Urea

Xanthan Gum

Water, Glycerin, Squalane, Hydrogenated Polydecene, Panthenol, Ethoxydiglycol, Dimethicone, Rosa Canina Fruit Oil, Cetearyl Alcohol, Acetyl Glutamine, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-9, Sh-Polypeptide-11, Copper Palmitoyl Heptapeptide-14, Heptapeptide-15 Palmitate, Glycyrrhiza Glabra Root Extract, Allantoin, Caprylyl Glycol, Butylene Glycol, Sodium Hyaluronate, Glycolic Acid, Lactic Acid/Glycolic Acid Copolymer, Disodium EDTA, Polyacrylamide, Potassium Sorbate, Sodium Benzoate, C13-14 Isoparaffin, Polyvinyl Alcohol, Methylparaben, Propylparaben, Laureth-7, Diazolidinyl Urea, Xanthan Gum

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Allantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics.

Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.

Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation.

It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh.

Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated.

This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%.

Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating.

Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.

This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.

Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.

You'll often find this ingredient used with other preservatives.

Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.

Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.

Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.

It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.

Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.

We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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