Best Urolithin A Supplement | Researched and Tested [2026]

Best Urolithin A Supplements

Can these supplements really boost longevity and improve overall health? We did the research and testing to find out.

Elsa is a senior editor and writer at Innerbody Research. She holds a Bachelor’s degree from the University of Minnesota, with a minor in Information Technology Management.

Dr. Segar is a board-certified cardiologist at the Texas Heart Institute and a member of Innerbody Research's Medical Review Board.

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Photo by Innerbody Research

Though increased life expectancy has been the focus of social policies for much of the last century, experts are finding that people’s “healthspans” — the average length of life lived without disease — haven't been able to keep up.1 People may be living longer, but researchers note that the “prevalence of disease has increased markedly” along the way.

Partly due to this realization, more and more research over the past few years has focused on finding ways to lengthen the average healthspan.2 Besides the positive impacts of lifestyle modifications, like eating right and exercising, some experts are investigating pharmacological or supplemental avenues.

One compound that’s recently been in the spotlight is urolithin A (UA), a postbiotic metabolite that’s promoted for its potential to improve mitochondrial health, boost athletic recovery, reduce the signs of skin aging, and more. But are these claims legitimate? And which urolithin A products are worth your investment? In this guide, we’ll break down everything you need to know. But if you’re in a hurry, check out our summary of recommendations below.

Summary of recommendations

Best overall: Timeline Mitopure Softgels

Best budget pick: Perpetua.Life Urolithin A Liposomal

Best urolithin A complex: Codeage Liposomal Urolithin A

Best topical urolithin A: Timeline Mito-Biotic Mitopure Skincare

Best urolithin A powder: Timeline Mitopure Powder

Effective doses of a branded form of urolithin A align Timeline’s product best with scientific research for optimal effectiveness and safety.

Timeline has an unfair advantage since it's owned by the Swiss company that developed Mitopure, the branded urolithin A that's been most widely studied. And being NSF Certified for Sport illustrates Timeline's dedication to transparency and safety. You can buy it directly from Timeline or find it at the company's storefront on Amazon. One-time purchases and month-to-month subscriptions on Amazon cost the same as buying direct. However, buying from Timeline gets you far better savings through subscription, which is significant since this isn't an inexpensive supplement.

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Why you should trust us

Over the past two decades, Innerbody Research has helped tens of millions of readers make more informed decisions involving staying healthy and living healthier lifestyles.

For our guide to the best urolithin A supplements, we spent over 160 hours researching urolithin A, including its optimal dosing, potential benefits, mechanism of action, side effects, and more. Our testers also thoroughly interacted with the companies and products mentioned in this guide, from asking customer support questions and purchasing items to investigating customer account options, getting hands-on with the supplements, and everything in between.

Additionally, like all health-related content on this website, this review was thoroughly vetted by one or more members of our Medical Review Board for accuracy.

How we evaluated urolithin A supplements

When evaluating urolithin A supplements, we considered four key, customer-centric criteria that our team often uses to evaluate similar supplemental products on the market. These four areas include a product’s safety, efficacy, cost, and convenience.

Before delving into the finer details of each category, it’s worth pointing out that all three brands that we chose performed well overall. However, each criterion does have a winner that stood out from the rest for one reason or another.

Let’s see how our top picks fared.

Safety

Winner: Timeline Mitopure

When it comes to supplement safety, it’s important to know that the FDA doesn’t regulate supplements in the same way it does prescription drugs. In the agency’s own words, it does not “have the authority to approve dietary supplements for safety and effectiveness, or to approve their labeling, before the supplements are sold to the public.”3

This means that it’s up to supplement manufacturers to take the necessary steps to ensure consumer safety. Thankfully, all of our top picks come from brands that take safety seriously. The chart below offers a quick overview of each company’s safety measures.

Third-party testing?

Tested for …

Safety and potency

Allergens

Free from “the big eight” major food allergens and gluten

Contains sunflower oil; otherwise, non-GMO and free from gluten, dairy, soy, and peanuts

Produced in a facility that processes fish and tree nuts; otherwise, free from soy, dairy, and gluten

Vegan?

Other certifications

NSF Certified for Sport

N/A

NSF Certified

Additional safety notes

FDA didn’t question GRAS notice in 2018; studies have been conducted on product

Based on the information in the chart, all of our top picks should be generally safe for most healthy adults. However, Timeline’s Mitopure supplement stands out in a few distinct ways. While Codeage’s product is NSF Certified, which is similarly impressive, Timeline’s NSF Certified for Sport status means that:

There are no unsafe levels of contaminants

The supplement contents match what’s listed on the label

There are no traces of any of the 290 substances banned by major athletic organizations

Additionally, Timeline’s Mitopure received a favorable GRAS review from the FDA in 2018, and it’s the only one of our top picks to have studies conducted on it (over a dozen pieces of research on Mitopure exist at the time of this writing).

Efficacy

Based on the scientific research available at the time of this writing, the doses of urolithin A used in all of our picks (500-1,000mg) are clinically relevant. While many trials have found 500mg to be potentially suitable for a wide range of health concerns, other research has found that 1,000mg may be the ideal dose for some needs (e.g., 500mg improved measures of leg strength, while 1,000mg improved aerobic endurance).5

But, out of our picks, only Mitopure has been subjected to multiple studies. In fact, most of the existing clinical research on urolithin A has been conducted using Mitopure.4 This branded form of urolithin A — created by a Swiss life sciences company called Amazentis SA — may improve aerobic endurance, boost leg muscle strength, protect the body against certain age-related conditions, and more.5 6 However, a member of our medical review board, Dr. Matt Segar, MD, points out, “Most human studies of urolithin A and Mitopure were designed and funded by Amazentis. Several authors of the studies are company-affiliated.” This is important to know because, even though this doesn’t completely discredit the research, it does mean that there is potential for bias.

Nonetheless, the possible benefits of urolithin A — Mitopure or not — are mainly due to the potential for the compound to activate a process in the body called “mitophagy” (mitochondrial autophagy). This is when your body breaks down dysfunctional mitochondria and replaces them with new, healthy ones.7 As humans age, mitophagy isn’t activated as often or performed as efficiently, meaning that unhealthy mitochondria can build up and lead to chronic diseases like cancer, dementia, and others.8

Now, besides the extensive research done on Mitopure, our other picks also have some support for their efficacy. For instance, the liposomal delivery of our picks from Perpetua.Life and Codeage may improve the stability and bioavailability of urolithin A (but more research on humans is needed to confirm this).9 And all of our top picks undergo potency analysis to ensure you’re getting the promised dose of urolithin A.

Those potency analyses are particularly important. According to the results of a 2024 study that tested the contents versus the label information of a few urolithin A supplements, “Results showed a significant deviation from the labeled amounts...” with levels of urolithin A ranging from -15.5% to +28.6% of what they should’ve been.10

Cost

Winner: Perpetua.Life Urolithin A Liposomal

If you’ve browsed urolithin A supplements before, you may have noticed that they tend to run on the expensive side. Often, the price of a good-quality urolithin A supplement can hover around $100. Our top picks from Timeline and Codeage fall into this category, but our pick from Perpetua.Life manages to maintain quality and safety for under $60 per bottle (or under $50 with a subscription).

Many inexpensive urolithin A supplements on the market don’t undergo adequate third-party safety testing or potency analysis, but Perpetua.Life’s Urolithin A Liposomal supplement undergoes both. Of course, Perpetua.Life’s product doesn’t contain clinically-tested Mitopure (like Timeline), but it does use liposomal delivery for potentially better bioavailability (like Codeage).5

The chart below breaks down the pricing information for single purchases and 1-month subscriptions of our top picks:

Single purchase

$59.00

$125.00

$99.99

Single purchase price per serving

$1.97

$4.17

$3.33

Subscription discount

20% off

10-32% off

Currently N/A

1-month subscription

$47.20

$112.50

1-month subscription price per serving

$1.57

$3.75

Urolithin A dose per serving

1,000mg

500mg

Servings per bottle

30

Free shipping?

On top of having the lowest single-purchase price and a generous 20% subscription discount, Perpetua.Life’s urolithin A technically comes with another way to reduce costs: easy dose adjustment. Since each 1,000mg dose of this supplement is two capsules, taking only one capsule would still give you 500mg of urolithin A — the same dose that’s been examined the most in research. This would turn each bottle of Perpetua.Life Urolithin A Liposomal capsules into a 2-month supply, lowering your monthly cost to about $30 for single purchases (or a little less than a dollar per dose). Of course, this cost-saving measure only really has potential if 500mg of urolithin A has shown promise for your concern. But, either way, Perpetua.Life still offers an affordable, well-dosed urolithin A supplement.

Insider Tip: Heading into 2026, Codeage’s subscription plan is temporarily unavailable. According to customer service representatives, the option will eventually be available again, but the exact date has yet to be determined. It’s also unclear whether or not the new Codeage subscriptions will have the previous 15% off discount. As information becomes available, we’ll update this guide accordingly.

Pivoting to look at the pricing of Timeline’s Mitopure, its subscriptions can be a bit confusing at first. Basically, even though Timeline’s subscription discount can be the highest of our top picks, it varies based on the length of your subscription. Higher discounts require longer subscriptions, which means paying more initially to save money over time. For instance, the highest possible discount — 32% off — is for the 12-month supply. This option costs $1,020 at checkout, but it lowers your monthly or per-bottle cost to $85. So, if you’re able to pay more, and you know you’ll be taking Mitopure for the foreseeable future, then a longer Timeline subscription could be a worthwhile investment.

But $85 per month is still at least $25 more than what you’d pay with Perpetua.Life, cementing the latter as our best urolithin A pick for those on a budget.

Convenience

Convenience can be a somewhat tricky criterion; some may prefer a gummy or drink mix to a capsule, while others could feel that having a generous return policy or guarantee is key. When it comes to our top urolithin A picks, none of them should be particularly inconvenient. Nonetheless, they all have distinct conveniences that they bring to the table, as shown in the chart below.

Money-back guarantee?

Yes; 30 days

Yes; 30 days (on first purchase)

Yes; 30 days (one bottle only)

Subscriptions available?

Currently unavailable

Subscription interval options

Every one, two, four, or 12 months

Every month

Supplement forms

Capsule, gummy, and powder

Capsule

By offering multiple supplement forms, several subscription options, and a newly added money-back guarantee, Timeline outdoes the competition for convenience. Previously, our winner in this category was Codeage, but with the company putting a temporary pause on subscriptions, it’s no longer the most convenient option.

However, the biggest convenience drawback with Timeline is the lack of subscription customization. If you happen to have a concern that could benefit from 1,000mg of urolithin A, then you’d be taking double the standard 500mg dose — turning a 1-month supply of Mitopure into a half-month one. So, for those customers, Timeline’s subscriptions could be inconvenient. Moreover, Timeline (unlike our other picks) doesn’t allow customers to modify subscriptions in their account; they need to contact customer service to make any adjustments that don’t involve changing their payment method.

For customers who would prefer to take 1,000mg of urolithin A per dose and still receive recurring subscription deliveries, Perpetua.Life may be the better option. However, it’s important to point out that Perpetua.Life’s guarantee and return policies are one and the same, and they only apply to a single bottle. The company even states, “It is advised you not purchase more than one bottle until you're certain our product is right for you.” This is very similar to Codeage’s guarantee, which only applies to your first purchase.

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How our top urolithin A supplement picks compare

Below, you’ll find a quick reference chart comparing some of the most important details of our top urolithin A supplement picks, such as dosing, safety, returns, and pricing (based on 1-month supplies).

Note: The Timeline information in the chart is based on its Mitopure supplements (the capsules, gummies, and powder). More details on Timeline’s Mito-Biotic Mitopure skincare products can be found under the brand’s dedicated section later in this guide.

Urolithin A dose

Capsules per dose

2 capsules

30 (or 60 if you take 500mg)

Other active ingredients

Trans-resveratrol (150mg); Betaine (102.5mg); CoQ10 (60mg)

Testing highlights

Third-party tested; NSF Certified for Sport; FDA had no questions to a GRAS notice

Third-party tested

Third-party tested; NSF Certified

Single purchase price

10-32% off (based on subscription length)

1-month subscription price

Subscription intervals

Shipping costs

Free shipping on all U.S. orders

Free shipping on orders $40+

Free shipping on orders $50+

Return or guarantee policy

30-day money-back guarantee (supplements only)

30-day refund policy on one bottle of product

30-day money-back guarantee on first purchase

When it comes to pill sizes, Perpetua.Life has the smallest of our top picks, while the capsules from Timeline and Codeage are more “standard” sized supplements. Our testers didn’t have issues taking any of these, but individuals who have difficulty swallowing pills may prefer the smaller size of Perpetua.Life’s capsules or even Timeline’s, which have a bit of a “slippery” or almost oily feeling to them that could make them go down a bit easier.

What is urolithin A?

Urolithin A is a bioavailable postbiotic produced by your gut bacteria after you eat certain foods (like berries, pomegranates, pecans, and walnuts) containing the polyphenols ellagitannins or ellagic acid.11 12

Useful postbiotics are a sort of “healthy waste” produced by probiotics after they consume prebiotics.13 When your gut bacteria break down ellagitannins or ellagic acid, urolithin A is what’s left over — or at least that’s what happens for some people. Researchers have found that only around 40% of people are able to produce urolithin A due to differences in individual gut microbiomes.6 Fortunately, other studies have found that the remaining 60% of people can “overcome” that limitation through supplementation.12

Most of the potential benefits of urolithin A are attributed to the compound’s effects on mitophagy.7 This is when your body “cleans up” damaged or excess mitochondria,8 then replaces them with new, healthy ones to maintain mitochondrial homeostasis.14 As you age, the rate and effectiveness of the mitophagy process decrease. When this happens, the gradual buildup of dysfunctional mitochondria can lead to increased inflammation, which is associated with a higher risk of chronic diseases, like cancer or dementia.8 15 So, if urolithin A can kickstart mitophagy, then it may lower your risk for chronic disease, increasing your healthspan and your lifespan.

We cover more about the potential benefits and applications of urolithin A under the “How does urolithin A work?” section.

Who is urolithin A for?

From what experts currently know about urolithin A, it could be a suitable supplement for any adult — not pregnant or breastfeeding — who’s interested in trying it. Since everyone’s mitophagy process slows down with age, a large population of adults could find some benefit from it.8 Of course, it’s always important to speak with your doctor first before starting a new supplement, just to make sure it’s safe for your unique situation.

Based on the available research, urolithin A may be particularly helpful for people concerned about chronic inflammation, healing an injury, improving athletic performance, or (in the case of topical urolithin A) reducing the signs of skin aging.

Who should look elsewhere?

While urolithin A may be able to promote better mitochondrial health by supporting mitophagy,7 there currently isn’t any research to suggest that the compound could benefit primary or genetic mitochondrial diseases (e.g., Leigh syndrome, Kearns-Sayre syndrome, Leber hereditary optic neuropathy, etc.).16 Some experts suggest that it could be worth investigating whether mitophagy activation could act as a “novel strategy” to treat these diseases, but that research hasn’t been conducted yet.17 18 19 When that happens, we’ll update this information.

Otherwise, urolithin A isn’t suitable for children or anyone taking a medication that may interact with it. (We cover those medications in the following section.)

Is urolithin A safe?

Urolithin A has demonstrated exceptional safety in the studies conducted on it thus far. According to a 2024 review, “There were no serious adverse events attributed directly to [urolithin A] reported in any of the studies. Observed adverse events such as myalgia and headaches were classified as mild to moderate and assessed as unrelated to the interventions.”20 This means that researchers ultimately determined that the headaches and muscle pain experienced by patients during the studies were not due to urolithin A supplementation.

However, as explained by the Alzheimer’s Drug Discovery Foundation in 2024, while urolithin A does have an impressive safety profile, its long-term safety has yet to be established.4

Also, while rare, some people can be allergic to pomegranates, which are rich in the polyphenols that are metabolized into urolithin A.21 This doesn’t necessarily mean that those with pomegranate allergies will have a reaction to urolithin A supplements, but it could be something to keep in mind. Additionally, skin irritation from polyphenols has been documented in some research, meaning that skincare products containing urolithin A may also have this risk.22

Finally, on the topic of pomegranate, since urolithin A is often derived from compounds of the fruit, it may interact with the same drugs (e.g., those metabolized by cytochrome P450, or CYP450, enzymes).23 24 These include but aren’t limited to:25

ACE inhibitors

Blood pressure medications

Statins (cholesterol-lowering medication)

Warfarin (blood thinner)

Sildenafil

Anticonvulsants

Sulfonylureas

Buspirone (an anti-anxiety medication)

Metformin

Piracetam (a nootropic drug)

Theophylline (used in asthma and COPD)

However, Dr. Segar notes, “Many of these interactions are based on mechanistic data, animal data, and isolated case reports.” This means that many of the potential interactions in the list above haven’t been confirmed in human studies.

Nonetheless, it’s recommended that you speak with your doctor before taking urolithin A — even if you’re perfectly healthy and not on any prescription medication. As more human research on the interactions between urolithin A and various medications becomes available, we’ll update this guide accordingly.

How does urolithin A work?

As mentioned earlier in this guide, the benefits of urolithin A are mainly attributed to its potential to kickstart mitochondrial autophagy or “mitophagy” — the process of your body clearing out old, dysfunctional mitochondria and replacing them with new, healthy ones.7 8 14

When dysfunctional mitochondria build up, the production of oxidative stress in the body may increase.8 This, in turn, increases the risk of developing various chronic and degenerative diseases, such as cancer, heart disease, kidney disease, Alzheimer’s disease, Parkinson’s disease, rheumatoid arthritis, and more.15

Besides increasing your disease risk, excess oxidative stress can also lead to:

More visible signs of skin aging (fine lines, wrinkles, etc.)15

Increased muscle atrophy26

Reduced muscle force generation26

Neuroinflammation27

Since urolithin A has the potential to help your body clean out dysfunctional mitochondria by supporting mitophagy, it may also be able to lower your risk of health concerns attributed to oxidative stress — increasing your healthspan and, possibly, your lifespan. This is supported by some of the existing research on the compound.

Let’s go over some key findings. (Note: Most of the clinical research on urolithin A thus far has been done using Mitopure.)4

Longevity

As we’ve discussed, urolithin A appears to be able to kickstart mitophagy to help clean out your body’s dysfunctional mitochondria and maintain mitochondrial homeostasis.7 8 14 By supporting this process, you may have a lower risk of developing various chronic diseases that can impact your lifespan.

As noted in a 2021 review, a couple of animal studies support urolithin A’s effects on longevity. In 2016, researchers found that urolithin A was able to extend the lifespan of a worm by 45%, and another study found it increased the survival rate of mice with Duchenne muscular dystrophy (DMD).6 Of course, more research on humans is needed.

Neuroinflammation

In a 2021 review, researchers explain that urolithin A “attenuates inflammation in various tissues.” Though most of the reviewed studies have been done using mice, urolithin A “consistently” inhibited neuroinflammation, leading researchers to suggest the compound could be beneficial in mediating certain effects of neurodegenerative diseases.28

Skin aging

Most of the research on urolithin A products for skin health was conducted by Amazentis SA, the creator of Mitopure and the owner of Timeline. The company sponsored three separate clinical trials, all with fairly positive outcomes.29 However, it’s worth pointing out that the research has yet to be published or peer-reviewed. When the trials are peer-reviewed, we’ll update this information. But, for now, it’s important to keep the possibility of biased results in mind.

The first trial found that a 1% urolithin A cream decreased the depth of facial wrinkles and improved subjects’ collagen production. The second trial used a “day cream, night cream, and serum,” all with a 1% urolithin A concentration, and found that the treatment led to “significant wrinkle reduction” in participants. The final trial focused on urolithin A for photodamaged skin (damage caused by UV light) and found that a 1% urolithin A treatment reduced skin redness by 14% versus placebo, meaning it could protect photodamaged skin or promote its healing after exposure.29

Muscle function and recovery

According to a 2023 review, urolithin A may “promote muscle protein synthesis” and mitigate muscle atrophy while improving muscle health and performance due to its effects on mitophagy.23 Additionally, a 2022 study on Mitopure found that daily doses of 500mg and 1,000mg (or 1g) for four months increased subjects’ leg muscle strength and, in the 1,000mg dose group, boosted their aerobic endurance.5

Timeline Mitopure and Mito-Biotic

Best overall, best powdered urolithin A, and best topical urolithin A

Pros

Branded form of urolithin A that has been examined in over a dozen studies

Dose of urolithin A is clinically relevant

Supplements are NSF Certified for Sport

Received favorable Generally Recognized as Safe (GRAS) review from the FDA

Products are non-GMO, vegan, cruelty-free, gluten-free, and free from major allergens

Skincare should be sensitive-skin friendly (no dyes or fragrances)

Supplements available in capsule, gummy, and powder forms

All products are HSA/FSA eligible through Truemed

Subscriptions can save you 10-32% off, depending on product and delivery interval

30-day money-back guarantee on supplements

Cons

Guarantee doesn’t apply to skincare products

More expensive than other urolithin A supplements

Capsules may leak, leading to wasted product and mess

Inactive ingredients in supplements may trigger rare allergies

Subscription management requires contacting customer service

No subscription customization available

Products weren’t packed very safely

The Timeline brand is owned and operated by Amazentis SA, the Swiss life sciences company that developed Mitopure. So, in a way, all Mitopure products bearing the Timeline brand are “straight from the source.” You might occasionally come across other urolithin A products containing Mitopure, but not all of those products are made equal; just because they contain the branded ingredient, it doesn’t mean that it’s the same product (e.g., same capsule, inactive ingredients, etc.) used in Mitopure-focused research. In fact, some non-Timeline Mitopure products we’ve come across even have doses well below what was used in successful studies. For example, the brand Pure Encapsulations offers a complex called Renual that contains Mitopure, but it’s only available in half (250mg) of the smallest dose that has seen positive outcomes in research (500mg).

Now, as mentioned earlier in this guide, Mitopure is the brand of urolithin A used in most clinical research (often in the form of Timeline’s capsules). Because of this, the Alzheimer’s Drug Discovery Foundation has dubbed it “the most well-validated form of urolithin A…”4 This isn’t to say other forms of urolithin A can’t be beneficial, but we do hope to see more research on non-Mitopure urolithin A in the future. As it stands, the current abundance of research focused specifically on Mitopure is a big reason why it won our choice for best overall.

Other reasons for our choice include:

Timeline’s Mitopure supplements are third-party tested and NSF Certified for Sport.

In 2018, Amazentis SA received a favorable Generally Recognized As Safe (GRAS) review of Mitopure from the FDA.

The Mitopure capsules, powder, and gummies from Timeline are free from “the big eight” major allergens (milk, eggs, fish, shellfish, peanuts, tree nuts, soybeans, and wheat).

Timeline products are produced in facilities that adhere to Good Manufacturing Practices (GMP) standards, along with those for food safety (FSSC 22000),30 quality management (ISO 9001),31 and proper cosmetics manufacturing (ISO 22716).32

Timeline offers Mitopure as supplements in capsule, powder, and gummy forms or as an ingredient in various skincare products in its Mito-Biotic line.

Continuing with that final point, Timeline is one of the only companies we’ve come across that offers urolithin A as a powder, gummy, or skincare product. There are plenty of urolithin A pills on the market, but the other forms and products are currently difficult — if not impossible — to find elsewhere.

Insider Tip: Despite the “-biotic” in the name, Timeline’s Mito-Biotic skincare products don’t contain any antibiotics or other prescription topical ingredients. The company likely uses “-biotic” because urolithin A is a postbiotic, as we covered earlier in this guide.

To learn more about Timeline and Mitopure, check out our full Mitopure review.

Timeline Mitopure and Mito-Biotic pricing information

All of the Mitopure supplements and Mito-Biotic skincare products from Timeline are available as either one-time buys or subscriptions, and all purchases made directly through the Timeline website ship for free in the U.S.

First, let’s cover the pricing of the Mitopure supplements. Interestingly, the price doesn’t change depending on the form you purchase; capsules, powder, and gummies all cost the same. Here’s how it all breaks down:

Single purchase (1-month supply)

$125

1-month supply subscription

$112.50 (10% off)

2-month supply subscription

$200

$100 (20% off)

4-month supply subscription

$380

$95 (24% off)

$3.17

12-month supply subscription

$1,020

$85 (32% off)

$2.83

Now, let’s go over the details and pricing of Timeline’s Mito-Biotic skincare products (they all contain a 1% concentration of Mitopure):

Gentle Cleanser

$55

$44

Amino acids, panthenol, and ceramides

Resurfacing Exfoliator

$70

$56

Plant-based salicylic acid, mandelic acid, and lactic acid

Firming Serum

$225

$180

Red algae, green tea, caffeine, and phytic acid

Dewy Cream

$160

Prickly pear extract, green tea, shea butter, and peptides

Barrier Cream

Eye Cream

$120

$96

Peptides, watercress extract, sodium hyaluronate

Insider Tip: When you subscribe to the Mitopure Softgels, Mito-Biotic Firming Serum, Mito-Biotic Dewy Cream, or Mito-Biotic Barrier Cream, you’re expected to keep the bottle you receive with your initial delivery. Timeline will send you refills at your selected subscription interval.

Previously, all purchases from Timeline were considered final sale, but the company has recently introduced a 30-day money-back guarantee for its supplements (skincare, unfortunately, isn’t covered). This is the same length as the policies from Codeage and Perpetua.Life, but those companies limit their guarantees to either your first purchase (Codeage) or first bottle (Perpetua.Life).

Perpetua.Life Urolithin A Liposomal

Best budget urolithin A supplement

Third-party tested for safety and potency in ISO-certified labs

Urolithin A dose is higher than many competing supplements (1,000mg)

Liposomal delivery may improve bioavailability of urolithin A

Vegan, non-GMO, gluten-free, and free from dairy, soy, and peanuts

Costs around half of what competitors charge for similar products

Halving the dose (one capsule; 500mg) can increase cost-effectiveness

All purchases meet free shipping threshold