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Avène Skin Recovery Cream Versus Biossance Squalane + Omega Repair Cream

Avène Skin Recovery Cream Versus Biossance Squalane + Omega Repair Cream This barrier-repair moisturizer is formulated around Squalane to strengthen the skin barrier and hydrate skin. This barrier-repair moisturizer is formulated around Squalane and Ceramide N

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

Avène Skin Recovery Cream Versus Biossance Squalane + Omega Repair Cream

This barrier-repair moisturizer is formulated around Squalane to strengthen the skin barrier and hydrate skin.

This barrier-repair moisturizer is formulated around Squalane and Ceramide NP to strengthen the skin barrier and hydrate skin.

What's inside

Key Ingredients

No key ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Paraffinum Liquidum

Glycerin

Glyceryl Stearate

Squalane

Cyclopentasiloxane

Cyclohexasiloxane

Serine

Carbomer

Tetrasodium EDTA

Triethanolamine

Water, Paraffinum Liquidum, Glycerin, Glyceryl Stearate, Squalane, Cyclopentasiloxane, Cyclohexasiloxane, Serine, Carbomer, Tetrasodium EDTA, Triethanolamine

Caprylic/Capric Triglyceride

Isoamyl Laurate

Butyrospermum Parkii Butter

Sorbitan Olivate

Cetearyl Olivate

Ceramide NP

Jojoba Esters

Sodium Hyaluronate

Euterpe Oleracea Sterols

Linoleic Acid

Oleic Acid

Linolenic Acid

Ethyl Linoleate

Tocopherol

Isoamyl Cocoate

Cetyl Palmitate

Sorbitan Palmitate

Cetearyl Alcohol

Ethylhexylglycerin

Sodium Hydroxide

Phenoxyethanol

Sodium Gluconate

Water, Squalane, Glycerin, Caprylic/Capric Triglyceride, Isoamyl Laurate, Butyrospermum Parkii Butter, Sorbitan Olivate, Cetearyl Olivate, Ceramide NP, Jojoba Esters, Sodium Hyaluronate, Euterpe Oleracea Sterols, Linoleic Acid, Oleic Acid, Linolenic Acid, Ethyl Linoleate, Tocopherol, Isoamyl Cocoate, Cetyl Palmitate, Sorbitan Palmitate, Cetearyl Alcohol, Ethylhexylglycerin, Carbomer, Sodium Hydroxide, Phenoxyethanol, Sodium Gluconate

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.

Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.

It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.

Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.

A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Squalane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).

It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.

This is due to how structurally similar it is to what your skin already produces.

Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.

Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.

No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).

Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.

This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Though squalane is often called an oil, it’s technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.

The term “oil-free” isn’t regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.

Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.

A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.

The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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