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Anua Azelaic Acid 10 Hyaluron Redness Soothing Serum Versus Biologique Recherche Complexe Iribiol Rebalancing and Purifying Serum for the Face

Anua Azelaic Acid 10 Hyaluron Redness Soothing Serum Versus Biologique Recherche Complexe Iribiol Rebalancing and Purifying Serum for the Face This calming serum is formulated around Azelaic Acid and Panthenol to calm redness and clear breakouts. This acne ser

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

Anua Azelaic Acid 10 Hyaluron Redness Soothing Serum Versus Biologique Recherche Complexe Iribiol Rebalancing and Purifying Serum for the Face

This calming serum is formulated around Azelaic Acid and Panthenol to calm redness and clear breakouts.

This acne serum is formulated around Gluconolactone and Niacinamide to clear breakouts and balance excess oil.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Azelaic Acid

Propylene Glycol

Sodium Hydroxide

Dipropylene Glycol

1,2-Hexanediol

Panthenol

Hydroxyethylcellulose

Betaine Salicylate

Glycerin

Biosaccharide Gum-1

Ethylhexylglycerin

Allantoin

Dipotassium Glycyrrhizate

Melia Azadirachta Leaf Extract

Camellia Sinensis Leaf Water

Sodium Hyaluronate

Melia Azadirachta Flower Extract

Niacinamide

Aloe Barbadensis Leaf Juice

Beta-Glucan

Centella Asiatica Extract

Centella Asiatica Leaf Extract

Centella Asiatica Root Extract

Madecassoside

Asiaticoside

Asiatic Acid

Madecassic Acid

Squalane

Zinc PCA

Butylene Glycol

Pentylene Glycol

Caprylyl/Capryl Glucoside

Hydrogenated Lecithin

Ceramide NP

Water, Azelaic Acid, Propylene Glycol, Sodium Hydroxide, Dipropylene Glycol, 1,2-Hexanediol, Panthenol, Hydroxyethylcellulose, Betaine Salicylate, Glycerin, Biosaccharide Gum-1, Ethylhexylglycerin, Allantoin, Dipotassium Glycyrrhizate, Melia Azadirachta Leaf Extract, Camellia Sinensis Leaf Water, Sodium Hyaluronate, Melia Azadirachta Flower Extract, Niacinamide, Aloe Barbadensis Leaf Juice, Beta-Glucan, Centella Asiatica Extract, Centella Asiatica Leaf Extract, Centella Asiatica Root Extract, Madecassoside, Asiaticoside, Asiatic Acid, Madecassic Acid, Squalane, Zinc PCA, Butylene Glycol, Pentylene Glycol, Caprylyl/Capryl Glucoside, Hydrogenated Lecithin, Ceramide NP

Gluconolactone

Lactic Acid

Ethoxydiglycol

Magnesium Chloride

Malic Acid

Vinegar

Phytic Acid

Citric Acid

Quillaja Saponaria Bark Extract

Cochlearia Armoracia Root Extract

Arctium Lappa Root Extract

Capsicum Frutescens Fruit Extract

Arnica Montana Flower Extract

Sulfur

Sodium Salicylate

Serine

Urea

Sorbitol

Tea-Lactate

Sodium Lactate

Sodium Benzoate

Water, Gluconolactone, Glycerin, Niacinamide, Propylene Glycol, Lactic Acid, Ethoxydiglycol, Magnesium Chloride, Malic Acid, Vinegar, Phytic Acid, Citric Acid, Quillaja Saponaria Bark Extract, Cochlearia Armoracia Root Extract, Arctium Lappa Root Extract, Capsicum Frutescens Fruit Extract, Arnica Montana Flower Extract, Sulfur, Allantoin, Sodium Salicylate, Serine, Urea, Sorbitol, Tea-Lactate, Sodium Lactate, Sodium Benzoate

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Allantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics.

Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.

Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation.

It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh.

Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated.

This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%.

Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating.

Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Propylene Glycol is a synthetic, colorless, odorless liquid that has been a staple in cosmetics for decades. It is a skin conditioning agent, humectant, and solvent.

As a humectant, it draw water to the skin to reduce flaking and restore suppleness. It's also a solvent that helps dissolve other actives and keeps formulas stable across temperature changes.

The CIR Expert Panel has confirmed this ingredient to be nontoxic and clinical studies show no sensitization at cosmetic use concentrations.

True allergic reactions are quite rare: a 15-year retrospective study of 6,751 patients found only 0.31% had a positive reaction (and less than half were considered clinically relevant).

It seemed that when sensitization does occur, it's most commonly linked to topical medication (like corticosteroids) and not cosmetics. Allergic contact dermatitis also appears largely limited to individuals with underlying skin conditions.

Overall, propylene glycol is a well-studied ingredient that most people can tolerate without issue.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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