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Act+Acre 3% Stem Cell Peptide Treatment Versus Necessaire The Scalp Serum

Act+Acre 3% Stem Cell Peptide Treatment Versus Necessaire The Scalp Serum What's inside Key Ingredients Benefits Concerns No concerns Ingredients Side-by-side Water Propanediol Pentylene Glycol Polyglyceryl-6 Caprylate Niacinamide Polyglyceryl-4 Caprate Butyle

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

Act+Acre 3% Stem Cell Peptide Treatment Versus Necessaire The Scalp Serum

What's inside

Key Ingredients

Benefits

Concerns

No concerns

Ingredients Side-by-side

Water

Propanediol

Pentylene Glycol

Polyglyceryl-6 Caprylate

Niacinamide

Polyglyceryl-4 Caprate

Butylene Glycol

Panthenol

Hydrolyzed Eruca Sativa Leaf

Hydrolyzed Walnut Extract

Sodium Gluconate

Menthol

Caffeine

Mentha Piperita Oil

Menthyl Lactate

Caprylhydroxamic Acid

Vitis Vinifera Fruit Meristem Cell Culture

Citric Acid

Sodium Benzoate

Potassium Sorbate

Panax Ginseng Root Extract

Dextran

Acetyl Tetrapeptide-3

Trifolium Pratense Flower Extract

Water, Propanediol, Pentylene Glycol, Polyglyceryl-6 Caprylate, Niacinamide, Polyglyceryl-4 Caprate, Butylene Glycol, Panthenol, Hydrolyzed Eruca Sativa Leaf, Hydrolyzed Walnut Extract, Sodium Gluconate, Menthol, Caffeine, Mentha Piperita Oil, Menthyl Lactate, Caprylhydroxamic Acid, Vitis Vinifera Fruit Meristem Cell Culture, Citric Acid, Sodium Benzoate, Potassium Sorbate, Panax Ginseng Root Extract, Dextran, Acetyl Tetrapeptide-3, Trifolium Pratense Flower Extract

Sodium Hyaluronate

Apium Graveolens Seed Extract

Camellia Sinensis Leaf Extract

Biotinoyl Tripeptide-1

Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-86

Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-9

Nicotiana Benthamiana Octapeptide-30 Sh-Oligopeptide-2

Sodium Tocopheryl Phosphate

1,2-Hexanediol

Glycerin

Water, Butylene Glycol, Propanediol, Sodium Hyaluronate, Acetyl Tetrapeptide-3, Niacinamide, Panthenol, Trifolium Pratense Flower Extract, Apium Graveolens Seed Extract, Camellia Sinensis Leaf Extract, Biotinoyl Tripeptide-1, Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-86, Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-9, Nicotiana Benthamiana Octapeptide-30 Sh-Oligopeptide-2, Sodium Tocopheryl Phosphate, Dextran, 1,2-Hexanediol, Caprylhydroxamic Acid, Citric Acid, Glycerin

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

This biometic peptide is designed to support hair growth.

According to a manufacturer, it stimulates hair growth by:

The manufacturer has found combining this ingredient with red clover extract (Capixyl) boosted benefits. Not only does it enforce the scalp's extracellular matrix, it also inhibits the enzyme that creates DHT, a hormone that leads to hair loss.

While this ingredient is promising, more research is still needed to confirm its full effectiveness.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Caprylhydroxamic Acid is a chelating agent that helps cosmetics stay fresh, stable, and consistent over time.

Chelating agents help prevent metal ions from binding to other ingredients. This helps prevent unwanted reactions and effects from using the product. It also helps prevent the growth of unwanted microbes in products that contain water.

Caprylhydroxamic Acid is often used with natural antimicrobial products as an alternative to preservatives.

Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.

Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.

However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.

Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.

In skincare formulas, citric acid can:

While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.

Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.

Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.

However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's skin is unique, we recommend a patch test if you are unsure.

Dextran is a sugar (polysaccharide) with skin hydrating properties.

Fun fact: Louis Pasteur first discovered this ingredient as a microbial product in wine.

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.

There are two forms of panthenol: D and L.

D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.

Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):

Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.

This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.

Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.

This ingredient is also referred to as pro-vitamin B5.

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

This extract comes from the flower more commonly known as red clover.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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