Educational guide
Aclaris Photon Sunscreen Gel SPF 50 Versus The Formula rx Hydrashield Vitamin C + Peptide Watery Gel Sunscreen SPF 50
Aclaris Photon Sunscreen Gel SPF 50 Versus The Formula rx Hydrashield Vitamin C + Peptide Watery Gel Sunscreen SPF 50 This hybrid sunscreen covers the full UV range and blocks ~98% of UVB at SPF 50. What's inside Key Ingredients Benefits Concerns Ingredients S
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Aclaris Photon Sunscreen Gel SPF 50 Versus The Formula rx Hydrashield Vitamin C + Peptide Watery Gel Sunscreen SPF 50
This hybrid sunscreen covers the full UV range and blocks ~98% of UVB at SPF 50.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Ethylhexyl Methoxycinnamate
Butyl Methoxydibenzoylmethane
Dicetyl Phosphate
Titanium Dioxide
Polysorbate 80
Aloe Barbadensis Leaf Juice
Ascorbyl Palmitate
Glycerin
Benzophenone-3
Phospholipids
Butylene Glycol
Polymethylsilsesquioxane
Cetearyl Alcohol
Phenoxyethanol
Sodium Levulinate
Potassium Sorbate
Stearic Acid
Ceteth-20 Phosphate
Zinc Oxide
Tocopherol
Dimethicone Crosspolymer
Allantoin
Glutathione
Honey Extract
Water, Ethylhexyl Methoxycinnamate, Butyl Methoxydibenzoylmethane, Dicetyl Phosphate, Titanium Dioxide, Polysorbate 80, Aloe Barbadensis Leaf Juice, Ascorbyl Palmitate, Glycerin, Benzophenone-3, Phospholipids, Butylene Glycol, Polymethylsilsesquioxane, Cetearyl Alcohol, Phenoxyethanol, Sodium Levulinate, Potassium Sorbate, Stearic Acid, Ceteth-20 Phosphate, Zinc Oxide, Tocopherol, Dimethicone Crosspolymer, Allantoin, Glutathione, Honey Extract
Propanediol
Octocrylene
Ascorbyl Glucoside
Diethylamino Hydroxybenzoyl Hexyl Benzoate
Centella Asiatica Extract
Ascorbic Acid
Sodium Hyaluronate
Panthenol
Polygonum Cuspidatum Root Extract
Ammonium Acryloyldimethyltaurate/Vp Copolymer
Dicaprylyl Carbonate
Scutellaria Baicalensis Root Extract
Glycyrrhiza Glabra Root Extract
Gold
Disodium EDTA
Pentapeptide-4
Camellia Sinensis Leaf Extract
Chamomilla Recutita Flower Extract
Ethylhexylglycerin
Sorbitol
Rosmarinus Officinalis Leaf Extract
Water, Propanediol, Butylene Glycol, Ethylhexyl Methoxycinnamate, Octocrylene, Ascorbyl Glucoside, Butyl Methoxydibenzoylmethane, Diethylamino Hydroxybenzoyl Hexyl Benzoate, Titanium Dioxide, Centella Asiatica Extract, Ascorbic Acid, Sodium Hyaluronate, Panthenol, Polygonum Cuspidatum Root Extract, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Dicaprylyl Carbonate, Scutellaria Baicalensis Root Extract, Glycyrrhiza Glabra Root Extract, Gold, Disodium EDTA, Pentapeptide-4, Camellia Sinensis Leaf Extract, Glutathione, Chamomilla Recutita Flower Extract, Phenoxyethanol, Ethylhexylglycerin, Sorbitol, Rosmarinus Officinalis Leaf Extract
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Also known as Avobenzone, this ingredient is an oil-soluble used to absorb the full spectrum of UVA rays (peak 357 nm).
It's one of the most effective UVA filters available but has a major caveat of photostability: avobenzone is susceptible to photodegradation.
This means it can lose efficacy when exposed to sunlight without the help of a stabilizing agent.
Studies show antioxidants (like vitamin E or vitamin C) and some UV filters (like octocrylene and Tinosorb S) can meaningfully improve its stability in a formulation.
The maximum allowable concentration according to regulation is 3% in the US + Canada, and 5% in the EU, Australia, China, Korea, and ASEAN countries.
It has a well-support safety profile: a comprehensive 2025 review found minimal toxicity with no evidence of carcinogenicity.
Overall, avobenzone is a safe and regulated ingredient used in sunscreen for over 40 years.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
This ingredient is also known as Octinoxate and is one of the oldest and most widely used chemical UV filters in skincare.
It has a simple job: soap up UVB radiation (290-320 nm), the wavelengths responsible for sunburn and a big chunk of long-term sun damage.
In formulas, it's always paired with a separate UVA filter because octinoxate solely protects skin from UVB.
Because it's an oil-soluble liquid, it's easy to blend into the oil phase of lotions/creams and gives a cosmetically elegant feel.
The one quirk about formulating this ingredient is photostability; the molecule slowly changes shape into a less effective version when sunlight hits it. So the longer you're in the sun, the weaker its protection gets. The drop can be more than 30% in some formulas.
It also doesn't play nice with Avobenzone (the common UVA filter) since avobenzone destabilizes octinoxate and the two degrade each other. But don't worry: brands have solved this issue by adding photostabilizers like Tinosorb S to prevent degradation and keep SPF stable under heavy UV exposure.
The maximum allowed level is 10% in the EU and Australia, 7.5% in the US and Canada, and 20% in Japan.
The Cosmetic Ingredient Review Panel has concluded this ingredient to be safe in cosmetics up to 10%.
One last thing worth knowing for context:
Octinoxate has been the subject of ongoing review in Europe where the Scientific Committee on Consumer Safety's (SCCS) 2025 final opinion is that this ingredient is an endocrine-active substance.
Lab and animal studies suggest it can act a bit like a hormone in the body (mildly mimicking estrogen and slightly blocking male hormones). It's important to know this hasn't really been shown to happen in everyday human use.
This ingredient is also banned in Hawaii over coral reef concerns.
Glutathione is a tiny protein-like molecule (a "tripeptide" build from 3 amino acids: glycine, cysteine, and glutamic acid) that your body already makes on its own.
Inside your body, it acts as one of the skin's main antioxidants that help fight against free radicals.
In skincare, it's best known as a brightening ingredient that slows down tyrosinase, the key enzyme that makes skin pigment. It also nudges the skin toward making a lighter type of pigment instead of a darker one.
This is why you'll see it in products aimed at dark spots and uneven tone.
A small number of real human trials have found a topical glutathione lotion:
The honest caveat is that the current evidence is still thin (few studies, small groups, short timelines). Glutathione also doesn't absorb into skin very easily so results tend to be modest and fade if you stop using it.
One thing worth clearing up:
The scary side effects you may have heard about come from glutathione injected intravenously, which has real safety concerns. Applying it topically is a completely different thing and has a clean track record.
Most human studies used it around 2% (as Glutathione or Glutathione Disulfide) and a 2% oxidized glutathione lotion and a 2% S-acyl glutathione cream are the concentrations with actual clinical data behind them.
There's no established "ideal" percentage yet but 1-2% is the evidence-backed range.
Allergy-wise, there is very low risk for this ingredient; it was well-tolerated across the topical trials. Only one participant had mild temporary redness that cleared up on its own and another study reported no adverse reactions at all.
One trial had ~10% of users drop out for irritation was using a combination cream that also had 10% azelaic acid so the irritation likely wasn't from the glutathione. There's no notable contact-allergy signal for topical glutathione in the literature but patch-testing before first use is still sensible for those with sensitive skin.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Titanium Dioxide (TD) is a mineral UV filter widely used in sunscreens and cosmetics.
It's one of only two UV filters officially classified as "mineral" by regulatory agencies (the other being Zinc Oxide).
A really common myth is that mineral filters work by reflecting UV light off your skin like tiny mirrors.
They don't only do that; modern research shows TD protects mostly by absorbing UV radiation, the same way chemical filters do.
When researchers measured this, reflection accounted for only about 4-5% of the protection (and less than SPF 2 on its own). The other ~95% comes from absorption: the UV photons hit the particle and their energy gets soaked up by its semiconductor band gap rather than bouncing off.
So "reflects vs. absorbs" was never really the right way to split mineral from chemical filters.
TD gives broad-spectrum protection that's strongest in the UVB and UVA-2 range and weaker in the UVA-1 range. Its UVA protection isn't quite as strong as Zinc Oxide's which is why you'll often see the two paired together.
Together, they make a solid broad-spectrum system.
TD is a great pick for sensitive, acne-prone, or redness-prone skin because it's non-irritating and chemically inert. Regulatory reviews classify it as a non-sensitizer and mild-to-non-irritant.
It's also unlikely to cause the "eye sting" some chemical filters are known for.
The main trade-off is cosmetic; TD can leave a white cast and has a thicker texture. This is why mineral sunscreens are often less cosmetically elegant than chemical or hybrid formulas (and harder to shade-match on deeper skin tones).
Formulators often use micronized or nano-sized TD to cut down on white case and improve spreadability. Smaller particles scatter less visible light so the formula looks less chalky while still filtering UV.
TD is almost always bundled with coatings like Alumina, Silica, Stearic Acid, or Dimethicone. These coatings do two important jobs:
TD can be used at up to 25% in a finished sunscreen; this is the regulatory ceiling in both the US and the EU.
In practice, the amount in any given product varies a lot depending on the target SPF and whether it's paired with other UV filters.
TD is one of the most heavily vetted sunscreen ingredients out there. It is approved as a UV filter in all major markets worldwide, including the US, EU, UK, Japan, Korea, China, Australia, and Canada.
The safety evidence is solid. There was an old worry that nano particles might absorb through skin into the body but multiple studies (including on damaged, sunburned, and UV-irradiated skin) have shown that TD stays on the surface and the layer of dead skin cells on top of everything else.
There's also no evidence of carcinogenicity, mutagenicity, or reproductive toxicity from dermal exposure of this ingredient.
For those who have seen the headline about a 2022 EU ban on TD, that was on TD as a food additive (a complete separate use from topical sunscreen).
There are ongoing questions about how nano-TD might affect marine ecosystems. As of now, there has been no conclusive evidence that any form of TD (or any other sunscreen filter) harms coral reefs or marine life.
The science is still developing and it's a space worth watching rather than packing over.
However, several destinations have reef-safety sunscreen rules that restrict certain chemical filters and steer visitors toward mineral, non-nano options. If you're traveling somewhere with these rules, a non-nano mineral sunscreen is the safe bet.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!