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6.8: Biotechnology

Feature: Reliable Sources Genetically modified foods, or GM foods, are foods produced from genetically modified organisms. These are organisms that have had changes introduced into their DNA using methods of biotechnology. Commercial sale of GM foods began in

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Feature: Reliable Sources

Genetically modified foods, or GM foods, are foods produced from genetically modified organisms. These are organisms that have had changes introduced into their DNA using methods of biotechnology. Commercial sale of GM foods began in 1994, with a tomato that had delayed ripening. By 2015, three major crops grown in the U.S. were raised mainly from GM seeds, including field corn, soybeans, and cotton. Many other crops were also raised from GM seeds, ranging from a variety of vegetables to sugar beets. Other sources of GM foods in our diet include meats, eggs, and dairy products from animals that have eaten GM feed, as well as a plethora of food products that contain some form of soy or corn products, such as soybean oil, soybean flour, corn oil, corn starch, and corn syrup. A quick glance at the ingredients list of most processed foods shows that these products are added to many of the items in a typical American diet. Most scientists think that GM foods are not any riskier to human health than conventional foods. Nonetheless, in many countries, including the U.S., GM foods are given more rigorous evaluations than conventional foods. For example, GM foods are assessed for toxicity, the ability to cause allergic reactions, and the stability of inserted genes. GM crops are also evaluated for possible environmental effects, such as outcrossing , which is the migration of genes from GM plants to conventional crops or wild plant species. Despite the extra measures used to evaluate GM foods, there is a lot of public concern about them, including whether they are safe to human health, how they are labeled, and their environmental impacts. These concerns are based on a number of factors, such as the worrying belief that scientists are creating entirely new species and a perceived lack of benefits to the consumer of GM foods. People may also doubt the validity of risk assessments, especially with regard to long-term effects. Also, since all the research on safety and usefulness is presented in scientific journals, it can be difficult for the public to be fully informed about the work being done. Over the past 50 years, there have been many hundreds of studies looking at how these crops affect the environment, the economy, and the health of humans and animals. The results of most of these studies are fairly clear. But, most people don't read the original findings because there are too many and because they can be difficult to understand. The National Academy of Sciences has written a report summarizing the research findings as well as public comments. They explain the reason for writing the report: "Consumers in the United States and abroad get conflicting information about GM crops. Proponents tout the benefits while opponents emphasize the risks. There was a need for an independent, objective study to examine what had been learned about GM crops, assesses whether initial concerns and promises were realized since their introduction, and investigates new concerns and recent claims."

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Related questions

01What Is the Human Genome?

The human genome refers to all the DNA of the human species. Human DNA consists of 3.3 billion base pairs and is divided into more than 20,000 genes onto 23 pairs of chromosomes. The human genome also includes noncoding sequences (e.g. intergenic region) of DNA, as shown in Figure \(\PageIndex{2}\).

Source: bio.libretexts.org ↗
02What Is the Genetic Code?

The genetic code consists of the sequence of nitrogen bases in a polynucleotide chain of DNA or RNA. The bases are adenine (A), cytosine (C), guanine (G), and thymine (T) (or uracil, U, in RNA). The four bases make up the “letters” of the genetic code. The letters are combined in groups of three to form code “words,” called codons . Each codon stands for (encodes) one amino acid unless it codes for a start or stop signal. There are 20 common amino acids in proteins. With four bases forming three-base codons, there are 64 possible codons. 61 codons are more than enough to code for the 20 amino acids, thus more than one codon codes for a single amino acid. Please find genetic codes in Table \(\PageIndex{1}\) or in appendix 1 .

Source: bio.libretexts.org ↗
03So how is it possible to know which genetic variants cause disease and which are passengers?

The way scientists look at disease variants is to compare the genetic makeup of a large number of people who have a specific disease with those who do not. This allows scientists to look for genetic variants that are more common in people with a disease compared to people without the disease. For example, if a particular genetic variant is present in 80 percent of patients with the disease but only 20 percent of the healthy population it suggests that this variant is increasing the risk of that disease. However, looking for a disease that is caused by variants in a single gene is the simplest example. There are many complex diseases where variants in many different genes might be involved. As well as the transcriptional and translational regulation of some enzyme production may vary due to the genetic variation in the enhancer and repressors of a gene. So, for this type of comparison to be effective very large groups of people need to be studied, usually in the tens of thousands, to find the variants that have subtle effects on disease risk. Researchers also try to pick individuals with similar phenotypes, in both the diseased and healthy groups, so that the disease genes are easier to identify and study.

Source: bio.libretexts.org ↗
04What Makes You...You?

This person has naturally red hair. Why is this hair red instead of some other color? And, in general, what causes specific traits to occur? There is a molecule in human beings and most other living things that is largely responsible for their traits. The molecule is large and has a spiral structure in eukaryotes. What molecule is it? With these hints, you probably know that the molecule is DNA.

Source: bio.libretexts.org ↗
05What Is Gene Expression?

Using a gene to make a protein is called gene expression . It includes the synthesis of the protein by the processes of transcription of DNA and translation of mRNA. It may also include further processing of the protein after synthesis. Gene expression is regulated to ensure that the correct proteins are made when and where they are needed. Regulation may occur at any point in the expression of a gene, from the start of the transcription phase of protein synthesis to the processing of a protein after synthesis occurs. The regulation of transcription is one of the most complicated parts of gene regulation in eukaryotic cells and is the focus of this concept.

Source: bio.libretexts.org ↗
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Peptide Therapy Guide Editorial Team

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