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111Skin Repair Serum NAC Y² Versus Estée Lauder Advanced Night Repair Synchronized Recovery Complex II

111Skin Repair Serum NAC Y² Versus Estée Lauder Advanced Night Repair Synchronized Recovery Complex II This barrier-repair serum is formulated around Sodium Ascorbyl Phosphate and Niacinamide to strengthen the skin barrier and calm redness. This barrier-repair

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

111Skin Repair Serum NAC Y² Versus Estée Lauder Advanced Night Repair Synchronized Recovery Complex II

This barrier-repair serum is formulated around Sodium Ascorbyl Phosphate and Niacinamide to strengthen the skin barrier and calm redness.

This barrier-repair serum is formulated around Bifida Ferment Lysate to strengthen the skin barrier.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Sorbitol

Isopropyl Myristate

Alcohol

Polyacrylate Crosspolymer-6

Sodium Ascorbyl Phosphate

Acetyl Cysteine

Escin

Niacinamide

Calendula Officinalis Flower Extract

Cistus Incanus Flower/Leaf/Stem Extract

Aloe Barbadensis Leaf Extract

Centella Asiatica Extract

Aesculus Hippocastanum Seed Extract

Lecithin

Beta-Sitosterol

Soy Isoflavones

Glycosphingolipids

Polyglyceryl-6 Laurate

Polyglyceryl-10 Oleate

Carbomer

Hydroxyacetophenone

1,2-Hexanediol

Caprylyl Glycol

Sorbitan Palmitate

Sodium Hydroxide

Phenylpropanol

Parfum

Water, Glycerin, Sorbitol, Isopropyl Myristate, Alcohol, Polyacrylate Crosspolymer-6, Sodium Ascorbyl Phosphate, Acetyl Cysteine, Escin, Niacinamide, Calendula Officinalis Flower Extract, Cistus Incanus Flower/Leaf/Stem Extract, Aloe Barbadensis Leaf Extract, Centella Asiatica Extract, Aesculus Hippocastanum Seed Extract, Lecithin, Beta-Sitosterol, Soy Isoflavones, Glycosphingolipids, Polyglyceryl-6 Laurate, Polyglyceryl-10 Oleate, Carbomer, Hydroxyacetophenone, 1,2-Hexanediol, Caprylyl Glycol, Sorbitan Palmitate, Sodium Hydroxide, Phenylpropanol, Parfum

Bifida Ferment Lysate

Methyl Gluceth-20

PEG-75

Bis-PEG-18 Methyl Ether Dimethyl Silane

Butylene Glycol

Propanediol

Cola Acuminata Seed Extract

Hydrolyzed Algin

Pantethine

Caffeine

Tripeptide-32

Ethylhexylglycerin

Sodium Rna

Bisabolol

Glycereth-26

Squalane

Sodium Hyaluronate

Oleth-3 Phosphate

Lactobacillus Ferment

Oleth-3

Oleth-5

Anthemis Nobilis Flower Extract

Faex Extract

Choleth-24

Hydrogenated Lecithin

Ceteth-24

Tocopheryl Acetate

Ethylhexyl Methoxycinnamate

Hexylene Glycol

Triethanolamine

Trisodium EDTA

BHT

Xanthan Gum

Phenoxyethanol

CI 14700

CI 19140

Water, Bifida Ferment Lysate, Methyl Gluceth-20, PEG-75, Bis-PEG-18 Methyl Ether Dimethyl Silane, Butylene Glycol, Propanediol, Cola Acuminata Seed Extract, Hydrolyzed Algin, Pantethine, Caffeine, Lecithin, Tripeptide-32, Ethylhexylglycerin, Sodium Rna, Bisabolol, Glycereth-26, Squalane, Sodium Hyaluronate, Oleth-3 Phosphate, Caprylyl Glycol, Lactobacillus Ferment, Oleth-3, Oleth-5, Anthemis Nobilis Flower Extract, Faex Extract, Choleth-24, Hydrogenated Lecithin, Ceteth-24, Tocopheryl Acetate, Ethylhexyl Methoxycinnamate, Hexylene Glycol, Carbomer, Triethanolamine, Trisodium EDTA, BHT, Xanthan Gum, Phenoxyethanol, CI 14700, CI 19140

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.

Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.

It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.

Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.

A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.

Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of phospholipids.

Thanks to its amphiphilic structure (water-loving head and oil-loving tail), it is a true multitasker:

It plays well with most ingredients and is typically used at 0.1-1%. However, concentrations up to 50% have been reported in moisturizers.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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