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A group of researchers from Massachusetts institutions have established a research institute focused on developing new drugs based on targeting every protein in humans, with initial funding of $15 million. The…
Read guide →Collaboration will focus on designing a small molecule to inhibit a protein, discovered by QIMR, that is linked to cancer survival. Cancer Therapeutics CRC and the Queensland Institute of Medical Research (QIM…
Read guide →Compound belongs to the spiroindolone class of drugs. A compound that shows promise for drug-resistant malaria has been discovered by scientists at the Novartis Institute for Tropical Diseases (NITD) in collab…
Read guide →Marine tunicate tadpoles developed brain plaques within 24 hours of APP administration, as reported in Disease Models & Mechanisms. San Diego State University researchers have discovered a potentially valuable…
Read guide →Investor opposition led firm to pull the plug on merger despite board support. CRO Charles River Laboratories is bowing to investor opposition by pulling out of its proposed $1.6 billion acquisition of rival f…
Read guide →Firm led a $30 million financing and inked a $200 million option agreement for one preclinical program. Novartis Option Fund led a $30 million Series B financing round for Avila Therapeutics and obtained an op…
Read guide →Novartis’ recombinant human relaxin-2 drug candidate RLX030 (serelaxin) reduced all-cause mortality in a placebo-controlled Phase III study involving 1,161 patients with heart failure, and met one of its two d…
Read guide →Scientists have developed a silicon-based peptide chip that they claim could form the basis of a real-time, point-of-care diagnostic platform. The team, headed by researchers at Stanford School of Medicine and…
Read guide →Caisson claims heparosan has numerous advantages compared with PEGylation. Novo Nordisk negotiated a potentially $100 million deal with Caisson Biotech to secure exclusive rights to use the latter’s heparosan-…
Read guide →Novartis will cut or transfer up to 4,000 pharmaceutical division jobs worldwide—about 6% of the division’s total 65,200 full-time employees—as part of the cost-cutting effort signaled by CEO Joseph Jimenez le…
Read guide →Coupling will accelerate the clinical development of A2B antagonists. Novartis acquired an option to Adenosine Therapeutics’ (ATL) A2B receptor antagonist program. Adenosine Therapeutics will continue to devel…
Read guide →Researchers based at the Florida campus of The Scripps Research Institute (TSRI) say they have created detailed fingerprints of a class of surface receptors that have proven highly useful for drug development.…
Read guide →Alex Philippidis Senior News Editor Genetic Engineering & Biotechnology News Which Traditional Drug Developers Generated the Most Value So Far This Year? Big pharma has a big public perception problem among Am…
Read guide →Novel therapeutics, even when they come from unexpected places, are a welcome addition to the armamentarium of drugs available to treat diseases. Now, a team of researchers from The University of Queensland ha…
Read guide →A team of investigators led by scientists at University College London has recently developed a quicker and less expensive method to determine which drugs currently on the market might be useful for treating o…
Read guide →View eBook Peptide mapping is an essential step in characterizing, identifying, and monitoring a wide range of properties of target proteins in biotherapeutic studies. Peptide mapping for biotherapeutic protei…
Read guide →Scientists at the University of Nottingham have engineered a self-assembling, living material resembling human sputum, or phlegm, which supports the growth of microbial 3D biofilms. The new platform will help …
Read guide →Engineers at the University of California, San Diego (UCSD) have developed modular nanoparticles that can be easily customized to target different biological entities such as tumors, viruses, or toxins. The su…
Read guide →Researchers are attempting to uncover the basics of how fat tissue is structured and, specifically, inflammation associated with obesity, in the hopes of unlocking the connection between the accumulation of fa…
Read guide →January 1, 1970 (Vol. , No. ) John Sterling Editor in Chief Genetic Engineering & Biotechnology News Combining natural organic atoms with metal complexes, scientists at The Wistar Institute have developed a ne…
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